BGC0001652: limazepine C biosynthetic gene cluster from Streptomyces sp. ICBB 8177
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Location: 1 - 25,568 nt. (total: 25,568 nt).
This entry is originally from NCBI GenBank KT381463.1.

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core biosynthetic genes
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0001652
Short description limazepine C biosynthetic gene cluster from Streptomyces sp. ICBB 8177
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KT381463.1
Compounds
  • limazepine C
  • limazepine D
  • limazepine E
  • limazepine F
  • limazepine A
Species Streptomyces sp. ICBB 8177 [taxonomy]
References
Chemical products information
limazepine C
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C15H16N2O3
Chemical database entries
NPAtlas
limazepine D
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C15H14N2O3
Chemical database entries
NPAtlas
limazepine E
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C15H16N2O3
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NPAtlas
limazepine F
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C14H16N2O2
Chemical database entries
NPAtlas
limazepine A
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C15H16N2O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AOC89000.1
  • lim1
 1 - 1815 (+) putative nonribosomal peptide synthetase
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  • AOC89001.1
  • lim2
 1870 - 6513 (+) putative nonribosomal peptide synthetase
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  • AOC89002.1
  • lim3
 6577 - 7836 (+) putative 3-deoxy-D-arabinoheptulosonate 7-phosphate (DAHP) synthase
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  • AWN56704.1
  • lim4
 7833 - 8624 (+) putative trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) oxidoreductase
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  • AWN56705.1
  • lim5
 8621 - 9337 (+) isochorismatase
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  • AOC89004.1
  • lim6
 9334 - 11310 (+) 2-amino-2-desoxyisochorismic acid (ADIC) synthase
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  • AOC89006.1
  • lim7
 11297 - 11878 (+) putative oxidoreductase
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  • AOC89005.1
  • lim8
 11900 - 13453 (+) putative monoxygenase
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  • AOC89008.1
  • lim9
 13544 - 14209 (-) putative O-methyltransferase
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  • AOC89009.1
  • lim10
 14495 - 15004 (+) putative L-DOPA-2,3-dioxygenase
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  • AOC89010.1
  • lim11
 15001 - 15942 (+) putative L-tyrosine hydroxylase
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  • AOC89011.2
  • lim12
 15939 - 16904 (+) putative F-420 dependent reductase
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  • AOC89012.1
  • lim13
 16897 - 17760 (+) putative isomerase
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  • AOC89013.1
  • lim14
 17835 - 19625 (+) putative gamma-glutamyltransferase-like hydrolase
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  • AOC89014.1
  • lim15
 19714 - 22005 (+) putative excinuclease ABC subunit A
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  • AOC89015.1
  • lim16
 22081 - 23256 (+) putative LLM class flavin-dependent oxidoreductase
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  • AOC89016.1
  • lim17
 23372 - 23854 (-) putative MarR family DNA-binding transcriptional regulator
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  • AOC89017.1
  • lim18
 24126 - 25568 (+) putative amine oxidase
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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