BGC0001658: macrotermycins biosynthetic gene cluster from Amycolatopsis sp. M39
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Location: 155,192 - 208,720 nt. (total: 53,529 nt).
This entry is originally from NCBI GenBank LWSF01000005.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001658
Short description macrotermycins biosynthetic gene cluster from Amycolatopsis sp. M39
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: LWSF01000005.1
Compounds
  • macrotermycins
Species Amycolatopsis sp. M39 [taxonomy]
References
Chemical products information
macrotermycins
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • A4R44_03174
  • OAP25798.1
  • degU_13
 155192 - 155845 (-) Transcriptional regulatory protein DegU
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  • A4R44_03175
  • OAP25799.1
  • liaS_9
 155869 - 156984 (-) Sensor histidine kinase LiaS
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  • A4R44_03176
  • OAP25800.1
  • eryCIII_1
 156975 - 158237 (-) Desosaminyl transferase EryCIII precursor
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  • A4R44_03177
  • OAP25801.1
  • laaA
 158472 - 159404 (+) L-amino acid amidase
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  • A4R44_03178
  • OAP25802.1
  • fenF
 159397 - 160356 (+) Malonyl CoA-acyl carrier protein transacylase
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  • A4R44_03179
  • OAP25803.1
  • acpP_2
 160349 - 160594 (-) Acyl carrier protein
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  • A4R44_03180
  • OAP25804.1
  • srfAA
 160828 - 162327 (+) Surfactin synthase subunit 1
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  • A4R44_03181
  • OAP25805.1
  • lcfB_5
 162527 - 163987 (+) Long-chain-fatty-acid--CoA ligase
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  • A4R44_03182
  • OAP25806.1
  • btrK_1
 163984 - 165198 (+) L-glutamyl-[BtrI acyl-carrier protein] decarboxylase
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  • A4R44_03183
  • OAP25807.1
  • mamA
 165195 - 165671 (+) Methylaspartate mutase S chain
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  • A4R44_03184
  • OAP25808.1
  • mutE
 165668 - 166459 (+) Methylaspartate mutase E chain
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  • A4R44_03185
  • OAP25809.1
 166401 - 166943 (+) Methylaspartate mutase E chain (MutE)
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  • A4R44_03186
  • OAP25810.1
 166943 - 168139 (+) Cytochrome P450 107B1
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  • A4R44_03187
  • OAP25811.1
 168293 - 170332 (+) Phenolphthiocerol synthesis polyketide synthase type I Pks15/1
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  • A4R44_03188
  • OAP25812.1
 170341 - 173619 (+) Phenolphthiocerol synthesis polyketide synthase type I Pks15/1
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  • A4R44_03189
  • OAP25813.1
 173685 - 173948 (-) hypothetical protein
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  • A4R44_03190
  • OAP25814.1
  • lgrE_2
 174055 - 174870 (-) Linear gramicidin dehydrogenase LgrE
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  • A4R44_03191
  • OAP25815.1
 175158 - 183599 (+) Phenolphthiocerol synthesis polyketide synthase type I Pks15/1
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  • A4R44_03192
  • OAP25816.1
 184098 - 184286 (-) UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain
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  • A4R44_03193
  • OAP25817.1
 184636 - 185052 (+) hypothetical protein
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  • A4R44_03194
  • OAP25818.1
  • eryCIII_2
 185273 - 186169 (+) Desosaminyl transferase EryCIII precursor
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  • A4R44_03195
  • OAP25819.1
 186428 - 191686 (+) Phenolphthiocerol synthesis polyketide synthase type I Pks15/1
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  • A4R44_03196
  • OAP25820.1
  • eryA_2
 191683 - 196446 (+) Erythronolide synthase, modules 1 and 2
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  • A4R44_03197
  • OAP25821.1
 196480 - 206856 (+) Phenolphthiocerol synthesis polyketide synthase type I Pks15/1
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  • A4R44_03198
  • OAP25822.1
  • drrA_7
 206970 - 207893 (+) Daunorubicin/doxorubicin resistance ATP-binding protein DrrA
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  • A4R44_03199
  • OAP25823.1
  • drrB_3
 207893 - 208720 (+) Daunorubicin/doxorubicin resistance ABC transporter permease protein DrrB
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
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