BGC0001693: nenestatin biosynthetic gene cluster from Micromonospora echinospora
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Location: 3,153 - 68,576 nt. (total: 65,424 nt).
This entry is originally from NCBI GenBank KY454837.1.

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core biosynthetic genes
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001693
Short description nenestatin biosynthetic gene cluster from Micromonospora echinospora
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: KY454837.1
Compounds
  • nenestatin
Species Micromonospora echinospora [taxonomy]
References
Chemical products information
nenestatin
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ARD70850.1
3153 - 3635 (+) hypothetical protein
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  • ARD70851.1
3788 - 4618 (-) ABC transporter
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  • ARD70852.1
4615 - 5574 (-) ABC transporter
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  • ARD70853.1
5670 - 6095 (-) glyoxalase/bleomycin resistance
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  • ARD70854.1
6215 - 6991 (-) hypothetical protein
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  • ARD70855.1
7114 - 7926 (-) SARP family regulatory protein
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  • ARD70856.1
9201 - 10049 (+) AraC family transcriptional regulator
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  • ARD70857.1
10479 - 11873 (+) NDP-hexose 2,3 dehydratase
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  • ARD70858.1
11953 - 12618 (-) hypothetical protein
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  • ARD70859.1
12655 - 13101 (-) carboxymuconolactone decarboxylase
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  • ARD70860.1
13171 - 14025 (-) Glutamyl hydrolase, amidotransferase
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  • ARD70861.1
14542 - 16191 (+) FAD-binding monooxygenase
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  • ARD70862.1
16329 - 17798 (-) Protoporphyrinogen oxidase
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  • ARD70863.1
17907 - 18959 (-) Nuclease
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  • ARD70864.1
19096 - 20577 (-) FAD-binding monooxygenase
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  • ARD70865.1
20574 - 22034 (-) FAD-binding monooxygenase
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  • ARD70866.1
22272 - 23000 (+) Short-chain dehydrogenase/reductase
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  • ARD70867.1
23075 - 23920 (+) NmrA family protein
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  • ARD70868.1
23983 - 24600 (-) DSBA oxidoreductase
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  • ARD70869.1
24663 - 24992 (-) Polyketide synthesis, cyclase
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  • ARD70870.1
25036 - 25821 (-) Polyketide synthesis, ketoreductase
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  • ARD70871.1
26017 - 27054 (+) O-methyltransferase
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  • ARD70872.1
27109 - 28620 (+) FAD-binding monooxygenase
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  • ARD70873.1
28647 - 29606 (+) cyclase
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  • ARD70874.1
29603 - 31039 (+) FAD-binding monooxygenase
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  • ARD70875.1
31026 - 32504 (+) FAD-binding monooxygenase
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  • ARD70876.1
32561 - 33304 (+) anthrone oxidase
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  • ARD70877.1
33373 - 35256 (-) hypothetical protein
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  • ARD70878.1
35237 - 35593 (-) 4Fe-4S ferredoxin
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  • ARD70879.1
35668 - 36462 (-) hypothetical protein
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  • ARD70880.1
36499 - 37992 (-) glutamine synthase
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  • ARD70881.1
37995 - 39413 (-) amidase
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  • ARD70882.1
39624 - 40910 (+) adenylosuccinate lyase
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  • ARD70883.1
40894 - 41295 (+) N-acetyltransferase
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  • ARD70884.1
41406 - 43172 (-) ABC transporter
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  • ARD70885.1
43575 - 43904 (-) Rieske (2Fe-2S) domain protein
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  • ARD70886.1
44148 - 44558 (+) glyoxalase
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  • ARD70887.1
44642 - 45442 (+) glyoxalase
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  • ARD70888.1
45500 - 47050 (-) secreted peptidase
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  • ARD70889.1
47571 - 48692 (-) glycosyltransferase
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  • ARD70890.1
48689 - 49708 (-) O-methyltransferase
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  • ARD70891.1
50074 - 51006 (+) N-methyltransferase
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  • ARD70892.1
51054 - 52055 (+) NAD-dependent epimerase/dehydratase
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  • ARD70893.1
52042 - 52767 (+) methyltransferase
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  • ARD70894.1
52764 - 53873 (+) aminotransferase
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  • ARD70895.1
53897 - 54508 (+) NDP-4-keto-6-deoxyhexose 3,5-epimerase
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  • ARD70896.1
54685 - 55680 (+) NDP-hexose-3-ketoreductase
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  • ARD70897.1
55735 - 56451 (-) hypothetical protein
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  • ARD70898.1
56544 - 57596 (-) glycosyltransferase
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  • ARD70899.1
57789 - 59009 (-) deoxysugar aminotransferase
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  • ARD70900.1
59205 - 60278 (+) dTDP-glucose 4,6-dehydratase
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  • ARD70901.1
60275 - 61546 (+) beta-ketoacyl synthase
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  • ARD70902.1
61543 - 62841 (+) chain length factor
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  • ARD70903.1
62829 - 63083 (+) acyl carrier protein
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  • ARD70904.1
63065 - 64102 (+) acyltransferase
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  • ARD70905.1
64219 - 65196 (+) acyltransferase/decarboxylase
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  • ARD70906.1
65225 - 65554 (-) acyl carrier protein
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  • ARD70907.1
65681 - 66136 (+) transcriptional regulator
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  • ARD70908.1
66215 - 67639 (+) propionyl-CoA carboxylase subunit beta
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  • ARD70909.1
67704 - 68576 (+) dTDP-1-glucose synthase
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
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