BGC0001715 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001715 (Niallia circulans)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	50,126	pelgipeptin	NRP	87%

BGC0001715 - Region 1 - NRPS

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Location: 1 - 50,126 nt. (total: 50,126 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 50,127
Label		BGC0001715

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001715.1	0.91	NRP	octapeptin C4	Bacillus circulans
BGC0000403.1	0.54	NRP	pelgipeptin	Paenibacillus elgii
BGC0001153.1	0.46	NRP	polymyxin B	Paenibacillus polymyxa
BGC0000408.1	0.46	NRP	polymyxin	Paenibacillus polymyxa
BGC0001192.1	0.46	NRP	colistin A, colistin B	Paenibacillus alvei
BGC0000389.1	0.42	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.40	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001050.1	0.40	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000400.1	0.38	NRP	paenibacterin	Paenibacillus sp. OSY-SE
BGC0000426.1	0.37	NRP	sevadicin	Paenibacillus larvae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001715.1	0.97	NRP	octapeptin C4	Bacillus circulans
BGC0000403.1	0.81	NRP	pelgipeptin	Paenibacillus elgii
BGC0001153.1	0.76	NRP	polymyxin B	Paenibacillus polymyxa
BGC0000408.1	0.76	NRP	polymyxin	Paenibacillus polymyxa
BGC0001192.1	0.76	NRP	colistin A, colistin B	Paenibacillus alvei
BGC0000389.1	0.73	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.72	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001050.1	0.72	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000400.1	0.70	NRP	paenibacterin	Paenibacillus sp. OSY-SE
BGC0000426.1	0.69	NRP	sevadicin	Paenibacillus larvae

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 50126:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-dab - dab - dab) + (D-X - phe - dab - dab) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

octA

Search NORINE for peptide: strict or relaxed

AMP-binding (466..877): dab

NRPSPredictor2: dab

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEISAIDK
Nearest Stachelhaus code:: dab
Stachelhaus code match:: 100% (strong)

AMP-binding (1996..2407): dab

NRPSPredictor2: dab

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEISAIDK
Nearest Stachelhaus code:: dab
Stachelhaus code match:: 100% (strong)

AMP-binding (3048..3459): dab

NRPSPredictor2: dab

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEISAIDK
Nearest Stachelhaus code:: dab
Stachelhaus code match:: 100% (strong)

octB

Search NORINE for peptide: strict or relaxed

AMP-binding (263..652): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWiIGAIvK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 80% (moderate)

AMP-binding (1770..2160): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAfTiGAICK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 80% (moderate)

AMP-binding (2801..3212): dab

NRPSPredictor2: dab

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEISAIDK
Nearest Stachelhaus code:: dab
Stachelhaus code match:: 100% (strong)

AMP-binding (3852..4263): dab

NRPSPredictor2: dab

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEISAIDK
Nearest Stachelhaus code:: dab
Stachelhaus code match:: 100% (strong)

octC

Search NORINE for peptide: strict or relaxed

AMP-binding (269..658): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWiIGAIvK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 80% (moderate)