LOCUS       BGC0001829             25136 bp    DNA     linear   BCT 05-JAN-2017
DEFINITION  Streptomyces chromofuscus TMC-86A operon, strain ATCC49982.
ACCESSION   BGC0001829
VERSION     BGC0001829
KEYWORDS    .
SOURCE      Streptomyces chromofuscus
  ORGANISM  Streptomyces chromofuscus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 04:45:53
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 25136
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..213
                     /gene="tmcA"
                     /operon="TMC-86A"
     CDS             1..213
                     /codon_start=1
                     /gene="tmcA"
                     /operon="TMC-86A"
                     /product="TmcA"
                     /protein_id="CUX96948.1"
                     /transl_table=11
                     /translation="MSDMGRRILEGVACGLSTAKLASRLYMSKNGVSYHLGELMREFQA
                     DNRTELVSRAYSVGLLKVGTWPPAT"
     source          1..25136
                     /db_xref="taxon:42881"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces chromofuscus"
                     /strain="ATCC 49982"
     operon          1..25136
                     /operon="TMC-86A"
     subregion       1..25136
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="NRP, Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25136
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            352..1020
                     /gene="tmcB"
                     /operon="TMC-86A"
     CDS             352..1020
                     /NRPS_PKS="Domain: Thioesterase (8-208). E-value: 2.8e-18.
                     Score: 59.0. Matches aSDomain:
                     nrpspksdomains_tmcB_Thioesterase.1"
                     /codon_start=1
                     /gene="tmcB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 107.5; E-value: 9.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /operon="TMC-86A"
                     /product="TmcB"
                     /protein_id="CUX96949.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.4e-12, bitscore:
                     37.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKELPDGCGGFLFELGGRFGETGSAPAADFRAAHERFLPDFLQL
                     VDRPALVIGHSLGALFAHNLVAALPPERAALVRTLVVSASKGPAVAAEEAPMPAAPFLV
                     RSASSVMEDLRTFGGTDPEFLEDPDFAQAAVGQLGHDLHLADTYTLPPGPPSAVPHLVW
                     YGQDDVTLAEADRLAWSGACARPPEHEGFPGGHFYLFERPEPAARLRELTGALTAEGFR
                     "
     aSDomain        376..975
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcB_Thioesterase.1"
                     /evalue="2.80E-18"
                     /label="tmcB_Thioesterase.1"
                     /locus_tag="tmcB"
                     /protein_end="208"
                     /protein_start="8"
                     /score="59.0"
                     /tool="antismash"
                     /translation="CGGFLFELGGRFGETGSAPAADFRAAHERFLPDFLQLVDRPALVI
                     GHSLGALFAHNLVAALPPERAALVRTLVVSASKGPAVAAEEAPMPAAPFLVRSASSVME
                     DLRTFGGTDPEFLEDPDFAQAAVGQLGHDLHLADTYTLPPGPPSAVPHLVWYGQDDVTL
                     AEADRLAWSGACARPPEHEGFPGGHFYLFERPEPAAR"
     CDS_motif       493..558
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcB_0001"
                     /evalue="2.70E-04"
                     /label="NRPS-te1"
                     /locus_tag="tmcB"
                     /protein_end="69"
                     /protein_start="47"
                     /score="13.6"
                     /tool="antismash"
                     /translation="RPALVIGHSLGALFAHNLVAAL"
     gene            1077..1934
                     /gene="tmcC"
                     /operon="TMC-86A"
     CDS             1077..1934
                     /codon_start=1
                     /gene="tmcC"
                     /operon="TMC-86A"
                     /product="TmcC"
                     /protein_id="CUX96950.1"
                     /transl_table=11
                     /translation="MTGTTGGQPLTPWLFTPGTSSFTEFMARYEPDLMPGGAQRAAGTP
                     RLTEDQIPHGTTVLALTYADGVMMAGDRRATMGNLIAQRDLEKVYPADEHTAVAFAGTV
                     GIALDMVRLYQVELAHFEKVEGTAMTLDGKANRLATMIRKNLGQAMQGLTVVPMLAGYD
                     LLAPEGEAGRIFSYDVTGGPYEMRDFYTVGSGSPYARGALKKLYRPGLSRREAALAALQ
                     ALYDAADDDSATGGPDVSRRIFPIVASITEEGYERMDEAQTEELSRLVVEQRLRQPEGP
                     TVTL"
     gene            2574..3596
                     /gene="tmcD"
                     /operon="TMC-86A"
     CDS             2574..3596
                     /codon_start=1
                     /gene="tmcD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 370.7; E-value: 9.1e-113)"
                     /gene_kind="biosynthetic-additional"
                     /operon="TMC-86A"
                     /product="TmcD"
                     /protein_id="CUX96951.1"
                     /sec_met_domain="fabH (E-value: 1.7e-111, bitscore: 362.1,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVRHEDKGRAAVVTGVGGWVPPDVVTNDDLSARLDTSDEWIRTR
                     TGIRTRHVISPGMATSDLAFEAGRRALESAGDPEVEAVVLATTTPDRLCPATAPEVAAR
                     LGLVGVPAFDISAVCAGFLYGLATAAGLIASGSARQVLLIGADAFTTIVDPKDRATAVI
                     FADGAGAVVLRAGRADEPGAVGPVILGSDGRFADLIQVPAGGSRQRSHSRSCGPGEEFF
                     RMDGRGTFRQAVERMSTASRQAVEAAGWRVEDVDRLAAHQANARILKAVADELAVPAGR
                     QLSNISRVGNTGAASIPLLLAQAAGDGSLAEGHRTLLTAFGGGLSWGAATLTWPALPTA
                     "
     gene            3635..3865
                     /gene="tmcE"
                     /operon="TMC-86A"
     CDS             3635..3865
                     /NRPS_PKS="Domain: PP-binding (2-68). E-value: 7.9e-17.
                     Score: 53.5. Matches aSDomain:
                     nrpspksdomains_tmcE_PP-binding.1"
                     /codon_start=1
                     /gene="tmcE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /operon="TMC-86A"
                     /product="TmcE"
                     /protein_id="CUX96952.1"
                     /sec_met_domain="PP-binding (E-value: 1.9e-17, bitscore:
                     53.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFETLKEVLVDKLEADPEEITPEATVEDAGLDSLSIVELSIILEK
                     DHAIAITDDELLAAPTIGDMARLMEERNAAL"
     aSDomain        3641..3838
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcE_PP-binding.1"
                     /evalue="7.90E-17"
                     /label="tmcE_PP-binding.1"
                     /locus_tag="tmcE"
                     /protein_end="68"
                     /protein_start="2"
                     /score="53.5"
                     /tool="antismash"
                     /translation="ETLKEVLVDKLEADPEEITPEATVEDAGLDSLSIVELSIILEKDH
                     AIAITDDELLAAPTIGDMARL"
     gene            4565..6238
                     /gene="tmcF"
                     /operon="TMC-86A"
     CDS             4565..6238
                     /codon_start=1
                     /gene="tmcF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 181.7; E-value:
                     3.8e-55)"
                     /gene_kind="biosynthetic-additional"
                     /operon="TMC-86A"
                     /product="TmcF"
                     /protein_id="CUX96953.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.3e-08, bitscore:
                     25.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.6e-18, bitscore:
                     55.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3e-17, bitscore:
                     53.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVERLADILRDRVNPTAVDATRELPEGLLEELRRDGFLNLQDSPD
                     VGGLGLSAYNTFRVVQAAASWSVPVALVLGIQTAVGSGTYLRALPPGDLYSYVEQRLLD
                     GIISGSADTEPAGASNSARQTRAVPTDDGETFLLTGEKIHIGNGPIADVVTVSAMLDED
                     GQDRPRLFFVETSDPGFRIRSRHEFMGVKGFPNAALVLDGVRVPRARMIVEVDPETEVR
                     ITPELTMAVVRGRLHLITAPGLAISKLCLEWSRNFLNRRTVDGRPLGDREEIQHMVSST
                     MADVFAIQALAEWSLLPADQPGLGINVAFEQNVTKAISAEICWRVADRTMDLLAGEGFE
                     TAPSKARRGVPALPLERFYRDARNLRISGGVSFLLQFWAARMSQFTYYGPDRARPTDAP
                     PPDPGRPAAPVQEPRADGLDPVNAGHLRFAAAETRRLGASCEEFAADHPAPGLFDHQHR
                     LIAYSRIADEILTMSVVLARAARLHREGGTGAQDLAHIYCARARDRLAGLWRQAEPETA
                     GPGHAAVSDAWLGGDDRYASLTDGVITDIPPTADTHPGER"
     gene            6235..12738
                     /gene="tmcG"
                     /operon="TMC-86A"
     CDS             6235..12738
                     /NRPS_PKS="Domain: Condensation_LCL (37-317). E-value:
                     2.2e-40. Score: 130.4. Matches aSDomain:
                     nrpspksdomains_tmcG_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (502-895). E-value:
                     7.8e-107. Score: 349.2. Matches aSDomain:
                     nrpspksdomains_tmcG_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1009-1077). E-value: 2.5e-14.
                     Score: 45.1. Matches aSDomain: nrpspksdomains_tmcG_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1095-1395). E-value:
                     4.5e-59. Score: 191.7. Matches aSDomain:
                     nrpspksdomains_tmcG_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1564-1950). E-value:
                     1.5e-83. Score: 272.5. Matches aSDomain:
                     nrpspksdomains_tmcG_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2055-2122). E-value: 4.1e-22.
                     Score: 70.0. Matches aSDomain: nrpspksdomains_tmcG_PCP.2"
                     /codon_start=1
                     /gene="tmcG"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     283.3; E-value: 5e-86)"
                     /gene_kind="biosynthetic"
                     /operon="TMC-86A"
                     /product="TmcG"
                     /protein_id="CUX96954.1"
                     /sec_met_domain="Condensation (E-value: 3e-49, bitscore:
                     157.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.9e-119, bitscore:
                     386.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8e-16, bitscore:
                     48.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKDKNRSGASAPREASPVASSPTEAATEAATAPARGLPLSVDQQ
                     AIWVHWQVDPDRTSHILHMPLLAEEGELDLVRVRAATRAVGERFPMLRARVVESGEEAA
                     LLWDDAPGIPVTEVRTDRPRAETVAHHGAFPFDLRQGPLARVQVLHGPDGTVLLIDVHH
                     LVFDGAACGPFLAAFRDAYAGKDLGPADDTTAHAEFARRQHELTHGPQGDTHREHWRRT
                     LGEDLPDPLRMPGRPGEPAFHEAVLDPDLLAAARTAAAAARVHPMIPLYAAFCLLLRAR
                     TGQDDLIVPTPYHGRSRELGERVGYFSNVLPLRHRLPAGVSHRRILRDLHHTLREGVRH
                     GALPYPALLRAAGLTGQLARTHAGQVNFQYWPAPPGDIDLTAIALDSPDSPGGTAVLRL
                     LAMEDYADHTLTVMLREDPRGSSLIWKDPTGAVGRATVEELAAAYPVVLAALIADLDAT
                     LGEPVPEAAVALDRPSPEASPMDERAWNTGTDAGFPDVSLPGLLRTRATATPDAVALSH
                     GARRLTYAELTDRAATLARGLAARGVRPGDLVALLLPRGVAQVEAVLATLFAGAVYVPL
                     DVAVPAERHRLILEDSQAVCLVTDGRRGVPGFTGPVIALDELRDVPEGDLPETDPGSPA
                     YVIFTSGTTGRPKGVVITHRNVVRLVVNDKLPYTFGPGDVWTMFHSYAFDVSVWEMFGC
                     FAHGGRLVVVGSDEAQDPQRLLALLRSENVTVLSQTPSAFAQLTGVHTSGQDPLDALRY
                     VIFAGEKLDPGSLAGFAARHPRTALVNMYGITEVTVHTTFREVTAQDIGTGRSNIGEPL
                     PTTTLFILGPDREPLPAGETGEIWVGGLGVAVGYLNRPELTAERFLPNPFGEGTLYRSG
                     DLARRLPDGTVEYVGRADQQVKIRGYRIEPGEIENRLLEHPAVEGAVVLAEAGPGGEAR
                     LVAYLLPHGTPPTTASLRTASLRGHLAARLPAYMVPARFLTVAAFPLTVNGKTDTKRLR
                     ETGTPLETGQDTDPPRTATARAVAEVWSDLLKVRDPGAGQSFFELGGHSLLAARTLRET
                     AERLGGPVPPLRTLFDHPVLQDFADALDRLTDRPGPAPAPAPVRTGGPLPASGFQQRIW
                     FDEQFLEGGALYQVPMVWRVRGRLDPAVLRTALHRMTERNEILRTAFVQRDGALWQEPG
                     APWQPEVDHQDLTTTTGHDRDHSQNQNQDHDREVTERLRAAARQPVDPASGRLLRITLF
                     DLPGEEQLLLLNTHHLVWDGGSAQPFLCELADCYAQALDPHAPPPAPRPQFRDALSGRA
                     AADVSTGLGHWAARLDGAPAHPAFEPPATPGPHGRVPVPLPAELPQLLGELGTQHGVSP
                     AMVFAAALAAALHGWTGQDDVTFGTPVAGRTDEEHAEVIGPLLNTAVLRSTTHRGETLG
                     ELLGRLRDTVLDAIDHQDVPFEDVVERLNPPRLPGRSPYVEVMLAVESEPPAPMLVGPG
                     QMTPYLFEDPETDAHAKFALTIDFREQDGRFTGHLAHRGDRISAEVARAFAGLLGRTVE
                     ALCGPRTQRVDEVPTAGPGELARITAFEKGAPAHPATTLPALLAERISQRPGAPAVESS
                     RGVLHYGELHTRALRLSARIRTAVQDREPIVAVVLGRGPDLVTAMLATWYAGCAFCPID
                     PDYPDERVRLTLKDVAAGAVVTEPGRSSATGDVPVLEVGDPSAYPGDGPLPEPHTPTPE
                     SPAYVLYTSGTTGRPKGAVLSHHGLAQLALWHMEAYDITPEDRASHLSSVGFDATQWEI
                     WPYLAAGACVVAHDRRVVVPELAPWLAKHRITMTYLSTPVAEAVWGTGADLPALRWMLF
                     AAAAQTRRPPADLGYRVANNYGPTEGSVVATWQPGPMPQDAPLNVVGRPITGKSVYVVD
                     PAGRRCPIGVTGELLIGGVGIALEYRGNPELTRERFLPAGPGGAPGPVYRTGDRARWRE
                     DGTLEFLGRVDRQLKVRGHRIEPQEVEAGLLADPRVLRAYVSGDATTLVAHVVPAAPDA
                     RDSRRVLDTLAARLPAHLVPDALMWLDELPTTAHGKVDVARLPRPGRDDLAGTQSWVEP
                     ADRLEQRIAAVWATVLDLERVGAADNFFDLGGNSLKLATLHARLLKELDREIPVHRLFE
                     FPTVRRLARFLAPEDDGPATPSPAARDDIDARAARWRTPAPRQSPAAHGTPRRNRNS"
     aSDomain        6346..7185
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcG_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.20E-40"
                     /label="tmcG_Condensation_LCL.1"
                     /locus_tag="tmcG"
                     /protein_end="317"
                     /protein_start="37"
                     /score="130.4"
                     /tool="antismash"
                     /translation="LPLSVDQQAIWVHWQVDPDRTSHILHMPLLAEEGELDLVRVRAAT
                     RAVGERFPMLRARVVESGEEAALLWDDAPGIPVTEVRTDRPRAETVAHHGAFPFDLRQG
                     PLARVQVLHGPDGTVLLIDVHHLVFDGAACGPFLAAFRDAYAGKDLGPADDTTAHAEFA
                     RRQHELTHGPQGDTHREHWRRTLGEDLPDPLRMPGRPGEPAFHEAVLDPDLLAAARTAA
                     AAARVHPMIPLYAAFCLLLRARTGQDDLIVPTPYHGRSRELGERVGYFSNVLPLRHRL"
     aSModule        6346..9465
                     /complete
                     /domains="nrpspksdomains_tmcG_Condensation_LCL.1"
                     /domains="nrpspksdomains_tmcG_AMP-binding.1"
                     /domains="nrpspksdomains_tmcG_PCP.1"
                     /locus_tags="tmcG"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6493..6534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0001"
                     /evalue="7.80E-03"
                     /label="Cy2"
                     /locus_tag="tmcG"
                     /protein_end="100"
                     /protein_start="86"
                     /score="9.0"
                     /tool="antismash"
                     /translation="ERFPMLRARVVESG"
     CDS_motif       6715..6780
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0002"
                     /evalue="1.90E-03"
                     /label="C3_LCL_132-143"
                     /locus_tag="tmcG"
                     /protein_end="182"
                     /protein_start="160"
                     /score="11.0"
                     /tool="antismash"
                     /translation="VHHLVFDGAACGPFLAAFRDAY"
     CDS_motif       7090..7176
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0003"
                     /evalue="1.20E-05"
                     /label="C5_LCL_267-296"
                     /locus_tag="tmcG"
                     /protein_end="314"
                     /protein_start="285"
                     /score="17.9"
                     /tool="antismash"
                     /translation="DLIVPTPYHGRSRELGERVGYFSNVLPLR"
     CDS_motif       7228..7314
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0004"
                     /evalue="6.30E+00"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="tmcG"
                     /protein_end="360"
                     /protein_start="331"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="HTLREGVRHGALPYPALLRAAGLTGQLAR"
     aSDomain        7741..8919
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcG_AMP-binding.1"
                     /evalue="7.80E-107"
                     /label="tmcG_AMP-binding.1"
                     /locus_tag="tmcG"
                     /protein_end="895"
                     /protein_start="502"
                     /score="349.2"
                     /tool="antismash"
                     /translation="RTRATATPDAVALSHGARRLTYAELTDRAATLARGLAARGVRPGD
                     LVALLLPRGVAQVEAVLATLFAGAVYVPLDVAVPAERHRLILEDSQAVCLVTDGRRGVP
                     GFTGPVIALDELRDVPEGDLPETDPGSPAYVIFTSGTTGRPKGVVITHRNVVRLVVNDK
                     LPYTFGPGDVWTMFHSYAFDVSVWEMFGCFAHGGRLVVVGSDEAQDPQRLLALLRSENV
                     TVLSQTPSAFAQLTGVHTSGQDPLDALRYVIFAGEKLDPGSLAGFAARHPRTALVNMYG
                     ITEVTVHTTFREVTAQDIGTGRSNIGEPLPTTTLFILGPDREPLPAGETGEIWVGGLGV
                     AVGYLNRPELTAERFLPNPFGEGTLYRSGDLARRLPDGTVEYVGRADQQVKIR"
     CDS_motif       7750..7785
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0005"
                     /evalue="1.40E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="tmcG"
                     /protein_end="517"
                     /protein_start="505"
                     /score="-0.3"
                     /tool="antismash"
                     /translation="ATATPDAVALSH"
     CDS_motif       7924..7965
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0006"
                     /evalue="1.80E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="tmcG"
                     /protein_end="577"
                     /protein_start="563"
                     /score="11.9"
                     /tool="antismash"
                     /translation="LATLFAGAVYVPLD"
     CDS_motif       8137..8196
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0007"
                     /evalue="2.10E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="tmcG"
                     /protein_end="654"
                     /protein_start="634"
                     /score="32.4"
                     /tool="antismash"
                     /translation="AYVIFTSGTTGRPKGVVITH"
     CDS_motif       8716..8805
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0008"
                     /evalue="2.90E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="tmcG"
                     /protein_end="857"
                     /protein_start="827"
                     /score="48.3"
                     /tool="antismash"
                     /translation="PAGETGEIWVGGLGVAVGYLNRPELTAERF"
     CDS_motif       8884..8949
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0009"
                     /evalue="2.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="tmcG"
                     /protein_end="905"
                     /protein_start="883"
                     /score="38.5"
                     /tool="antismash"
                     /translation="YVGRADQQVKIRGYRIEPGEIE"
     aSDomain        9262..9465
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcG_PCP.1"
                     /evalue="2.50E-14"
                     /label="tmcG_PCP.1"
                     /locus_tag="tmcG"
                     /protein_end="1077"
                     /protein_start="1009"
                     /score="45.1"
                     /tool="antismash"
                     /translation="RAVAEVWSDLLKVRDPGAGQSFFELGGHSLLAARTLRETAERLGG
                     PVPPLRTLFDHPVLQDFADALDR"
     aSDomain        9520..10419
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcG_Condensation_LCL.2"
                     /domain_subtype="Condensation_LCL"
                     /evalue="4.50E-59"
                     /label="tmcG_Condensation_LCL.2"
                     /locus_tag="tmcG"
                     /protein_end="1395"
                     /protein_start="1095"
                     /score="191.7"
                     /tool="antismash"
                     /translation="PLPASGFQQRIWFDEQFLEGGALYQVPMVWRVRGRLDPAVLRTAL
                     HRMTERNEILRTAFVQRDGALWQEPGAPWQPEVDHQDLTTTTGHDRDHSQNQNQDHDRE
                     VTERLRAAARQPVDPASGRLLRITLFDLPGEEQLLLLNTHHLVWDGGSAQPFLCELADC
                     YAQALDPHAPPPAPRPQFRDALSGRAAADVSTGLGHWAARLDGAPAHPAFEPPATPGPH
                     GRVPVPLPAELPQLLGELGTQHGVSPAMVFAAALAAALHGWTGQDDVTFGTPVAGRTDE
                     EHAEVIGPLLNTAVLRSTT"
     aSModule        9520..12600
                     /complete
                     /domains="nrpspksdomains_tmcG_Condensation_LCL.2"
                     /domains="nrpspksdomains_tmcG_AMP-binding.2"
                     /domains="nrpspksdomains_tmcG_PCP.2"
                     /locus_tags="tmcG"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9583..9702
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0010"
                     /evalue="4.90E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="tmcG"
                     /protein_end="1156"
                     /protein_start="1116"
                     /score="47.8"
                     /tool="antismash"
                     /translation="ALYQVPMVWRVRGRLDPAVLRTALHRMTERNEILRTAFVQ"
     CDS_motif       9949..10011
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0011"
                     /evalue="2.50E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="tmcG"
                     /protein_end="1259"
                     /protein_start="1238"
                     /score="17.0"
                     /tool="antismash"
                     /translation="HHLVWDGGSAQPFLCELADCY"
     CDS_motif       10321..10410
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0012"
                     /evalue="9.10E-10"
                     /label="C5_LCL_267-296"
                     /locus_tag="tmcG"
                     /protein_end="1392"
                     /protein_start="1362"
                     /score="31.0"
                     /tool="antismash"
                     /translation="DVTFGTPVAGRTDEEHAEVIGPLLNTAVLR"
     CDS_motif       10459..10575
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0013"
                     /evalue="1.70E-17"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="tmcG"
                     /protein_end="1447"
                     /protein_start="1408"
                     /score="55.7"
                     /tool="antismash"
                     /translation="RDTVLDAIDHQDVPFEDVVERLNPPRLPGRSPYVEVMLA"
     aSDomain        10927..12084
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcG_AMP-binding.2"
                     /evalue="1.50E-83"
                     /label="tmcG_AMP-binding.2"
                     /locus_tag="tmcG"
                     /protein_end="1950"
                     /protein_start="1564"
                     /score="272.5"
                     /tool="antismash"
                     /translation="ERISQRPGAPAVESSRGVLHYGELHTRALRLSARIRTAVQDREPI
                     VAVVLGRGPDLVTAMLATWYAGCAFCPIDPDYPDERVRLTLKDVAAGAVVTEPGRSSAT
                     GDVPVLEVGDPSAYPGDGPLPEPHTPTPESPAYVLYTSGTTGRPKGAVLSHHGLAQLAL
                     WHMEAYDITPEDRASHLSSVGFDATQWEIWPYLAAGACVVAHDRRVVVPELAPWLAKHR
                     ITMTYLSTPVAEAVWGTGADLPALRWMLFAAAAQTRRPPADLGYRVANNYGPTEGSVVA
                     TWQPGPMPQDAPLNVVGRPITGKSVYVVDPAGRRCPIGVTGELLIGGVGIALEYRGNPE
                     LTRERFLPAGPGGAPGPVYRTGDRARWREDGTLEFLGRVDRQLKVR"
     CDS_motif       11107..11148
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0014"
                     /evalue="2.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="tmcG"
                     /protein_end="1638"
                     /protein_start="1624"
                     /score="11.4"
                     /tool="antismash"
                     /translation="LATWYAGCAFCPID"
     CDS_motif       11332..11391
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0015"
                     /evalue="5.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="tmcG"
                     /protein_end="1719"
                     /protein_start="1699"
                     /score="28.1"
                     /tool="antismash"
                     /translation="AYVLYTSGTTGRPKGAVLSH"
     CDS_motif       11875..11964
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0016"
                     /evalue="3.70E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="tmcG"
                     /protein_end="1910"
                     /protein_start="1880"
                     /score="41.6"
                     /tool="antismash"
                     /translation="PIGVTGELLIGGVGIALEYRGNPELTRERF"
     CDS_motif       12049..12114
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcG_0017"
                     /evalue="3.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="tmcG"
                     /protein_end="1960"
                     /protein_start="1938"
                     /score="32.2"
                     /tool="antismash"
                     /translation="FLGRVDRQLKVRGHRIEPQEVE"
     aSDomain        12400..12600
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcG_PCP.2"
                     /evalue="4.10E-22"
                     /label="tmcG_PCP.2"
                     /locus_tag="tmcG"
                     /protein_end="2122"
                     /protein_start="2055"
                     /score="70.0"
                     /tool="antismash"
                     /translation="EQRIAAVWATVLDLERVGAADNFFDLGGNSLKLATLHARLLKELD
                     REIPVHRLFEFPTVRRLARFLA"
     gene            12735..18890
                     /gene="tmcH"
                     /operon="TMC-86A"
     CDS             12735..18890
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (6-423). E-value:
                     5.4e-149. Score: 488.5. Matches aSDomain:
                     nrpspksdomains_tmcH_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (539-829). E-value: 1.4e-55.
                     Score: 180.6. Matches aSDomain:
                     nrpspksdomains_tmcH_PKS_AT.1"
                     /NRPS_PKS="Domain: cMT (1292-1465). E-value: 7.4e-52.
                     Score: 167.6. Matches aSDomain: nrpspksdomains_tmcH_cMT.1"
                     /NRPS_PKS="Domain: PCP (1656-1719). E-value: 1.9e-13.
                     Score: 42.3. Matches aSDomain: nrpspksdomains_tmcH_PCP.1"
                     /codon_start=1
                     /gene="tmcH"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 257.6; E-value:
                     3.5e-78)"
                     /gene_kind="biosynthetic"
                     /operon="TMC-86A"
                     /product="TmcH"
                     /protein_id="CUX96955.1"
                     /sec_met_domain="PP-binding (E-value: 6.4e-11, bitscore:
                     32.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.3e-149, bitscore:
                     488.5, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.4e-56, bitscore: 180.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTNQQIAVIGMAARMPGSTGIPGFWADLRAGREGLTRFTTEQSL
                     AAGVDPALSRHPNYIPVRGTIDGGDRFDHSFFGYSPAEAATIDPQQRVFLEVASTALDD
                     AGIDPARLNGWIGVYAGSDITPDRTPGEGELLSQVIGAEKDFVATRVAYKLGLRGPALA
                     VQTACSTSLVAVHQACNALLSHDCDVALAGGVSLRLPQWTGYQYSEGHIMSRDGHCRPF
                     DADGSGTVPSSGAGVVALRRLEDALASGDRVLAVIRGWALNNDGGSKVGYTAPSVTGQR
                     DVIRLALARAGADPADIGCVEAHGTATRIGDPIEMAALTSAFRDSTDHVGTTWLGAVKS
                     NIGHTGAAAGVAGLIKTVLQLHHREIAPTVHYRSPNPALNLAESPFRIATEVQPWDTEG
                     PLLAGVSSFGIGGTNAHVVLESAPRLTRTAQTARPRVFPLSAHSPWALEKLRTSVADAL
                     TAPAPGSTSAPASTFVPASASASDDGTEDRLGDVAFTLAEGRRRLPYRTAVVAGDRESL
                     AAALRAPADPVEHRGATPAVAFVFPGHGTLHQGAGAAAHRLLPEFRRVFDEAALIVRER
                     YGLDLSALVTGQDAPVEEITFQQLALFTLGYALGRQLRVWGVRPASMMGNSVGEYVVAA
                     LAGVWNLEDALSLVHLRGRGMLSAAPGRMVAVVRRPGRELAIPDGVTLAIDAPHQLVLS
                     GEAEPVMKAHRTWEAEGWSCRILEIDRASHSPMMDAPAAELRAVAATTPTGGTDLGDTV
                     VVSTLTGEAVEPGHLTDPGHWGDHLRGTVQLRRAIGTLLDAPHDLVVELGPGQSTLRGL
                     RMHPDWNTATPAIPALGRSADQETESVLELCATLWEHGVAVDLAGLLDADEPSITELPA
                     HPYEPKPLPARPTTATAAAPEAPGHPEPAALAAPETHPTLTTDAWTSISRRLSAHSAAA
                     VGERLAAELGLPATDDRFTGLTASVVVAELPDDDDRAAPSALADRARTAGVQLLLLGRE
                     VFDVLDDSIEAAALPSPAAEWLGHRETAGDRTTLLDIGPAGRPDWLPAPWPGATRYAWR
                     GSGWWALLPRPVPVEPVTDAPRVALVTDDPDATVLAADLAAAGVHVASLTGDGPPPARP
                     TAGTIAATQTWRAGSARLSQRPELNTRVDRYSAGLIARFALERAGLRPGDRIAASELRH
                     RLNPGERLTRFFDFLLRSLVEEDVLRPGQVDGADGYLVAAGPQDLLAAGAGLGEVDGLH
                     RLLDSIAAELPAVFDGEKEPVAVLWPDGDDSMLRSWLPDNRLEIYDGGFCLDALEETVR
                     SLHRTWGDRPLRILEVGGGHGLFTWQLLEGWQDRDNVDYHFTDISTLLVRRAAKYARTN
                     GVRGVRFSTYDMTRDPVEQGLAAGSFDLVIAYNVIHVAPSVHTALGHLRSLLSPSGAVS
                     LVEVTDVTRWSHLLWGLAPGWWDFDDELRSDSIVLDAATWRRALAESGLPEITVVPDGV
                     PSDHTLMIAAPSRATDGAPAAPPFPDVDLVLSVLRSPDERTAHEATARWKSLRSEGPLA
                     ATPGVLLSTGPLDGATRALLDSPADADWTHLHADRFGAAVLDALPEVLGQPWLPRTVRL
                     RAPEIPDTVPASAAPAPMAPADVPETLRPAAAPAPAGPDARLEQALPAAPAAPAAAPVA
                     EPVAPVPAVAGPSGALAALDELWRYELGVPRSRAEDDFFALGGESLAAVHLLARVRDVC
                     GIKVPMSDFTRDPTYGFLAGLVGSVPQPRQQAQSEPQPQQHTQHQQHAQHQQHAQPQQQ
                     AQAQQQSQRRAGTRTPADSPNLMTLNDAGEGTPLFLSAPAAGSALCYRGLAKHLGDRPL
                     YGLETPGLHDGRAPLSRLEDIANHHVELIRSIQPDGPYLLGGWSFGMMLSHEIARQIIA
                     DGGAVALLSGVDGYLPNTGGMPMVTQPGFLLGGLVYKTQAVLGLGGAQPAGANGPEPDD
                     RILRIADVTRWRRQRARAGRQEKTAADFVSVHNHSIDAMFRYVPQPVNCPAVILKAGLN
                     ERGRLRLERGLRGLYTAVEVRSVAGDHWTVMDRRNAPGLATQLNQALRQHDPLTQEENH
                     "
     aSDomain        12753..14003
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcH_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="5.40E-149"
                     /label="tmcH_PKS_KS.1"
                     /locus_tag="tmcH"
                     /protein_end="423"
                     /protein_start="6"
                     /score="488.5"
                     /tool="antismash"
                     /translation="IAVIGMAARMPGSTGIPGFWADLRAGREGLTRFTTEQSLAAGVDP
                     ALSRHPNYIPVRGTIDGGDRFDHSFFGYSPAEAATIDPQQRVFLEVASTALDDAGIDPA
                     RLNGWIGVYAGSDITPDRTPGEGELLSQVIGAEKDFVATRVAYKLGLRGPALAVQTACS
                     TSLVAVHQACNALLSHDCDVALAGGVSLRLPQWTGYQYSEGHIMSRDGHCRPFDADGSG
                     TVPSSGAGVVALRRLEDALASGDRVLAVIRGWALNNDGGSKVGYTAPSVTGQRDVIRLA
                     LARAGADPADIGCVEAHGTATRIGDPIEMAALTSAFRDSTDHVGTTWLGAVKSNIGHTG
                     AAAGVAGLIKTVLQLHHREIAPTVHYRSPNPALNLAESPFRIATEVQPWDTEGPLLAGV
                     SSFGIGGTNAHVVLESAP"
     aSModule        12753..17891
                     /complete
                     /domains="nrpspksdomains_tmcH_PKS_KS.1"
                     /domains="nrpspksdomains_tmcH_PKS_AT.1"
                     /domains="nrpspksdomains_tmcH_cMT.1"
                     /domains="nrpspksdomains_tmcH_PCP.1"
                     /locus_tags="tmcH"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       13209..13256
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcH_0001"
                     /evalue="3.30E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="tmcH"
                     /protein_end="174"
                     /protein_start="158"
                     /score="16.1"
                     /tool="antismash"
                     /translation="GPALAVQTACSTSLVA"
     CDS_motif       13635..13679
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcH_0002"
                     /evalue="2.70E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="tmcH"
                     /protein_end="315"
                     /protein_start="300"
                     /score="10.4"
                     /tool="antismash"
                     /translation="VEAHGTATRIGDPIE"
     CDS_motif       13740..13784
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcH_0003"
                     /evalue="1.30E-02"
                     /label="PKSI-KS_m6"
                     /locus_tag="tmcH"
                     /protein_end="350"
                     /protein_start="335"
                     /score="8.6"
                     /tool="antismash"
                     /translation="GAVKSNIGHTGAAAG"
     aSDomain        14352..15221
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcH_PKS_AT.1"
                     /evalue="1.40E-55"
                     /label="tmcH_PKS_AT.1"
                     /locus_tag="tmcH"
                     /protein_end="829"
                     /protein_start="539"
                     /score="180.6"
                     /tool="antismash"
                     /translation="VFPGHGTLHQGAGAAAHRLLPEFRRVFDEAALIVRERYGLDLSAL
                     VTGQDAPVEEITFQQLALFTLGYALGRQLRVWGVRPASMMGNSVGEYVVAALAGVWNLE
                     DALSLVHLRGRGMLSAAPGRMVAVVRRPGRELAIPDGVTLAIDAPHQLVLSGEAEPVMK
                     AHRTWEAEGWSCRILEIDRASHSPMMDAPAAELRAVAATTPTGGTDLGDTVVVSTLTGE
                     AVEPGHLTDPGHWGDHLRGTVQLRRAIGTLLDAPHDLVVELGPGQSTLRGLRMHPDWNT
                     ATPAIPALG"
     CDS_motif       14583..14702
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcH_0004"
                     /evalue="6.60E-16"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="tmcH"
                     /protein_end="656"
                     /protein_start="616"
                     /score="50.4"
                     /tool="antismash"
                     /translation="GVRPASMMGNSVGEYVVAALAGVWNLEDALSLVHLRGRGM"
     aSDomain        16611..17129
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcH_cMT.1"
                     /domain_subtype="cMT"
                     /evalue="7.40E-52"
                     /label="tmcH_cMT.1"
                     /locus_tag="tmcH"
                     /protein_end="1465"
                     /protein_start="1292"
                     /score="167.6"
                     /tool="antismash"
                     /translation="RPLRILEVGGGHGLFTWQLLEGWQDRDNVDYHFTDISTLLVRRAA
                     KYARTNGVRGVRFSTYDMTRDPVEQGLAAGSFDLVIAYNVIHVAPSVHTALGHLRSLLS
                     PSGAVSLVEVTDVTRWSHLLWGLAPGWWDFDDELRSDSIVLDAATWRRALAESGLPEIT
                     VVPDGVPSDH"
     CDS_motif       16881..16910
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcH_0005"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m6"
                     /locus_tag="tmcH"
                     /protein_end="1392"
                     /protein_start="1382"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="SVHTALGHLR"
     aSDomain        17703..17891
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcH_PCP.1"
                     /evalue="1.90E-13"
                     /label="tmcH_PCP.1"
                     /locus_tag="tmcH"
                     /protein_end="1719"
                     /protein_start="1656"
                     /score="42.3"
                     /tool="antismash"
                     /translation="LDELWRYELGVPRSRAEDDFFALGGESLAAVHLLARVRDVCGIKV
                     PMSDFTRDPTYGFLAGLV"
     CDS_motif       18276..18347
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcH_0006"
                     /evalue="7.80E-11"
                     /label="NRPS-te1"
                     /locus_tag="tmcH"
                     /protein_end="1871"
                     /protein_start="1847"
                     /score="34.3"
                     /tool="antismash"
                     /translation="QPDGPYLLGGWSFGMMLSHEIARQ"
     gene            18890..20185
                     /gene="tmcI"
                     /operon="TMC-86A"
     CDS             18890..20185
                     /codon_start=1
                     /gene="tmcI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 416.4; E-value:
                     1.8e-126)"
                     /gene_kind="biosynthetic-additional"
                     /operon="TMC-86A"
                     /product="TmcI"
                     /protein_id="CUX96956.1"
                     /sec_met_domain="p450 (E-value: 2.5e-32, bitscore: 101.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTIDPNTFNTDPFPLLHRLREEAPVHQVEVLDGLGRPRWLITRY
                     EDALKALNDLRFSNELFAGMGPADDAGEAEPSLVAQAIKKAEAVQGRAMANLDPPDHTR
                     LRKLVVRSFSAKRMEALRPQVQEVTDALLDTVAGQDEFDLLETLAYPLSIRMVCTLLGV
                     PADGVDVFRGAAAVLAGFMNDDDWARETLRSLEGFDVYVRQLVADKRDDPRDDMLSDLI
                     HSTEEGGRLTEEELVAMAGLMIFAGHETTVQLITNAVLALHQNPRQMAALRADHGLLSA
                     MTDEVMRYDGPINPGINRVAREDIEIGGVTIPKGASVVIATAAANRDPRAFTDPDRFDI
                     TRSPDTVHLGFGHGIHYCLGARLAKIEAECAIGTLLRRYPRIALATEPENLRWRPGFLR
                     MAEEFRIRVDAPSPPADVPAHSPHRAGENAHV"
     gene            20178..22154
                     /gene="tmcJ"
                     /operon="TMC-86A"
     CDS             20178..22154
                     /NRPS_PKS="Domain: AMP-binding (73-469). E-value: 4.8e-93.
                     Score: 303.8. Matches aSDomain:
                     nrpspksdomains_tmcJ_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (576-645). E-value: 3.6e-19. Score:
                     60.6. Matches aSDomain: nrpspksdomains_tmcJ_PCP.1"
                     /codon_start=1
                     /gene="tmcJ"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     330.7; E-value: 2.2e-100)"
                     /gene_kind="biosynthetic"
                     /operon="TMC-86A"
                     /product="TmcJ"
                     /protein_id="CUX96957.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-101, bitscore:
                     329.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-13, bitscore:
                     41.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDSGSASHALVENTEGDLGVWPVTRPVPPGWRPAGHQGSHTSCL
                     TEADRRGRERPAGAPTPPEGDAGTLLELFRRTVENHPARPAVSDREHTYTYTALNRHSD
                     GLAQALLARGVRPGDHIAYLLPRGVAPFVVLLATLKAGAAYVPLDPTAPDDRLRLLIDH
                     SGATTVITHPEMAGRLDGLATARLMEYAPGDHADPKPGPATAAAPRQGASVLFTSGSTG
                     VPKAVLLEHRNLAQFAENPALPALTPQDRIGHVSNLAFDAFHWETWCAFAAGAEVVTLP
                     TMPDLIGGDMRRELKQRRITAMLVPTLAFNHLAHEQPETFSSLRILATGGDVVSPGACR
                     DLLAAGFAGQLVNLYGPTEAATACSAHPVTDTDHHGSVPIGRALEGIGLHILDETLTEV
                     APGSVGQLHIGGPGVARGYHGRPGLTAERFLPDPHGAPGGRLYATGDLAVRGEDGLLRY
                     VGRTDDQVKVRGYRIEPREVERELARHHQVRDVAVVVGGEGVDRYLAALVVLYGDSSFA
                     ALREAAASSMPDYMVPSAFISIPEMPSNDRGKRDLARLREIVTDHQKHRADRVAPSDPV
                     EIRLADFWKDLISVDEVGLTDDFFALGGNSLQAFRLRRRIVKELGVEVSNREILVTSEL
                     GALADLVRSKTGLVPSRKEDDLV"
     aSDomain        20397..21584
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcJ_AMP-binding.1"
                     /evalue="4.80E-93"
                     /label="tmcJ_AMP-binding.1"
                     /locus_tag="tmcJ"
                     /protein_end="469"
                     /protein_start="73"
                     /score="303.8"
                     /tool="antismash"
                     /translation="FRRTVENHPARPAVSDREHTYTYTALNRHSDGLAQALLARGVRPG
                     DHIAYLLPRGVAPFVVLLATLKAGAAYVPLDPTAPDDRLRLLIDHSGATTVITHPEMAG
                     RLDGLATARLMEYAPGDHADPKPGPATAAAPRQGASVLFTSGSTGVPKAVLLEHRNLAQ
                     FAENPALPALTPQDRIGHVSNLAFDAFHWETWCAFAAGAEVVTLPTMPDLIGGDMRREL
                     KQRRITAMLVPTLAFNHLAHEQPETFSSLRILATGGDVVSPGACRDLLAAGFAGQLVNL
                     YGPTEAATACSAHPVTDTDHHGSVPIGRALEGIGLHILDETLTEVAPGSVGQLHIGGPG
                     VARGYHGRPGLTAERFLPDPHGAPGGRLYATGDLAVRGEDGLLRYVGRTDDQVKVR"
     aSModule        20397..22112
                     /complete
                     /domains="nrpspksdomains_tmcJ_AMP-binding.1"
                     /domains="nrpspksdomains_tmcJ_PCP.1"
                     /locus_tags="tmcJ"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20583..20624
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcJ_0001"
                     /evalue="4.30E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="tmcJ"
                     /protein_end="149"
                     /protein_start="135"
                     /score="19.7"
                     /tool="antismash"
                     /translation="LATLKAGAAYVPLD"
     CDS_motif       20811..20870
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcJ_0002"
                     /evalue="5.10E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="tmcJ"
                     /protein_end="231"
                     /protein_start="211"
                     /score="25.2"
                     /tool="antismash"
                     /translation="ASVLFTSGSTGVPKAVLLEH"
     CDS_motif       21378..21464
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcJ_0003"
                     /evalue="3.20E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="tmcJ"
                     /protein_end="429"
                     /protein_start="400"
                     /score="51.4"
                     /tool="antismash"
                     /translation="PGSVGQLHIGGPGVARGYHGRPGLTAERF"
     CDS_motif       21549..21614
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tmcJ_0004"
                     /evalue="2.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="tmcJ"
                     /protein_end="479"
                     /protein_start="457"
                     /score="35.8"
                     /tool="antismash"
                     /translation="YVGRTDDQVKVRGYRIEPREVE"
     aSDomain        21906..22112
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tmcJ_PCP.1"
                     /evalue="3.60E-19"
                     /label="tmcJ_PCP.1"
                     /locus_tag="tmcJ"
                     /protein_end="645"
                     /protein_start="576"
                     /score="60.6"
                     /tool="antismash"
                     /translation="EIRLADFWKDLISVDEVGLTDDFFALGGNSLQAFRLRRRIVKELG
                     VEVSNREILVTSELGALADLVRSK"
     gene            22151..23377
                     /gene="tmcK"
                     /operon="TMC-86A"
     CDS             22151..23377
                     /codon_start=1
                     /gene="tmcK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 336.3; E-value: 4e-102)"
                     /gene_kind="biosynthetic-additional"
                     /operon="TMC-86A"
                     /product="TmcK"
                     /protein_id="CUX96958.1"
                     /sec_met_domain="p450 (E-value: 2e-24, bitscore: 75.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPTIDLTDPELFLGEDAGPIFRQLRHNDPVHRHPLPDGGGFWA
                     LTRYADVETAYNDHTSLSSEGGPMLGGSFRSAADPSAGRMLVASDLPRQRHIRQQVHRA
                     FSNGMLRRIATQVTTLVDTAVRRAVADGGCDFATDIAPELPAGAIMAMMGVSHTEAHEL
                     IGMTRRMIGFRDPVFADPGEDERIGLAVVQAEIFEFFAELLADRRKNPKDDLVSMLLQA
                     RRNGRPWPEEDILFNCMNVAVGGNETSSYTACAGILALHRNPTQKALLQADPELTDGAV
                     NEMLRWSSTNAYVMRQAVRDFKIGGRLIQDGDTVTLWNASANFDETRFPDPDTFDVTRT
                     PNRHLSFGIGIHRCIGAMLAQIELGILVRHMTDSRVSFTVSGPVRRLRSNFIRGTTSLP
                     LTMTATSGP"
     gene            23661..24212
                     /gene="tmcL"
                     /operon="TMC-86A"
     CDS             23661..24212
                     /codon_start=1
                     /gene="tmcL"
                     /operon="TMC-86A"
                     /product="TmcL"
                     /protein_id="CUX96959.1"
                     /transl_table=11
                     /translation="MRVAPLWCHDGVMDLTPYVDTLRRELAVAAEAGGDEARELAERLT
                     APLESATRLAMLNVLSAATDEITRELAPGSVDVRLRGLDPDFVVTPPPADSAPAAPAAP
                     AEPFKASAPADGDEGGTARVNLRLPAHLKTRAEEAANREGLSVNAWLVRAVSSAVDGGT
                     RPRATEKTQTFGQSFTGWVR"
     gene            24294..25136
                     /gene="orf+1"
                     /operon="TMC-86A"
     CDS             24294..25136
                     /codon_start=1
                     /gene="orf_1"
                     /operon="TMC-86A"
                     /product="Orf+1"
                     /protein_id="CUX96960.1"
                     /transl_table=11
                     /translation="MPSFDTPVPISVTAHVEAGSIQFTAGDRLDTVADVRPRDPKRDQD
                     VRAADQTEITYASGVLTVRTPKSSMFGRTGAVDVTVELPAGSRIDMTGAWAQVFGEGRL
                     GEVRVKISSGDVRLDATGPLKLTASHGSITVDRVDGTAEITTSSGSLRLGLVDGAAVLK
                     NSHGTTTVDAATGELRVSGANGDIEIRRAEDSVTATTAHGALRVSEVAHGTVQLETSFG
                     AIEVGVREGTAAWLDVSSGSGQVRNTLTVSETPERTEDAVKIRARTRHGNIDIRRAKV"
ORIGIN
        1 gtgagcgaca tgggccgcag gattcttgag ggtgtggcgt gcggtctgtc caccgcgaaa
       61 ctggcgtccc ggctctacat gagcaagaac ggtgtttcgt accacctggg cgagctgatg
      121 agggaattcc aggcggacaa ccggaccgag ctggtctcca gggcctactc ggtgggtctg
      181 ctgaaggtcg gaacgtggcc gccggccacg tgacaggatt tctctccggt gtgaagggtg
      241 atgtgttcca tgtccatgtc tgtgtcgtac cacggccttc cgggggccga tgccccggtc
      301 cggttgatcg cttttcatca cgccgggggg tccgcctcct cgttcctgcc ggtggtgaag
      361 gagctcccgg acggctgtgg cgggttcctc ttcgagctcg gcgggcggtt cggtgagacg
      421 gggagcgctc cggccgccga cttccgtgcg gcgcacgaac gtttccttcc ggactttctc
      481 caactggtcg accggccggc cctggtgatc gggcacagcc tcggtgccct gttcgcgcac
      541 aatctcgtcg cggcgctgcc gccggagcgg gcggccctgg tcaggacgct cgtggtctcc
      601 gcgtccaagg ggccggccgt ggccgcggag gaggccccga tgcccgccgc ccccttcctc
      661 gtacggtccg cttccagcgt catggaggac ctgcgtacgt tcggcgggac cgatccggag
      721 ttcctggagg acccggactt cgcccaggcc gcggtcggcc agctcgggca cgatctgcat
      781 ctggccgata cctacaccct gccgcccggt ccgccgtcgg ccgtcccgca cctggtctgg
      841 tacgggcagg acgacgtcac cctggcggag gcggaccggc tggcctggtc cggggcgtgc
      901 gcgcggccgc cggaacacga ggggttcccc ggcggccatt tctatctctt cgaaaggccg
      961 gaaccggccg cccggctccg ggaactgacc ggggctctca ccgcggaggg tttccggtga
     1021 tcggatattt ggtaggttcc gaagatcttc ggcccattgc agaaagggga caccgagtga
     1081 ctgggaccac cggcgggcag ccgctgacac cctggctgtt cacccccgga acgtcgtcgt
     1141 tcacggagtt catggcgagg tacgaaccgg acctgatgcc cggcggcgca cagcgtgccg
     1201 ccggaacccc gaggctgacg gaggatcaga ttccgcacgg caccaccgtg ctcgccctca
     1261 cctatgcgga cggcgtcatg atggccggtg accggcgcgc gacgatggga aatctcatcg
     1321 cccagcgtga cctggaaaag gtgtatcccg cggacgagca cacggcggtg gcattcgccg
     1381 gcaccgtcgg gatagcgctg gacatggtgc ggctctacca ggtcgagctg gcccacttcg
     1441 aaaaggtcga gggcacggcg atgaccctgg acggtaaggc gaaccggctc gccaccatga
     1501 tccggaagaa cctcggccag gccatgcagg gcctcaccgt ggtacccatg ctcgccgggt
     1561 acgacctgct cgccccggag ggcgaggcgg gccggatctt cagctacgac gtgaccggcg
     1621 gaccgtacga gatgcgggac ttctacacgg tgggatccgg ttccccctat gcccgggggg
     1681 cgttgaagaa gctctaccgg ccggggctct cgcgccggga agccgcgctg gccgcgctcc
     1741 aggcgctcta cgacgcggcg gacgacgact cggcgaccgg cggcccggac gtctcccggc
     1801 ggatcttccc gatcgtcgcg tcgatcaccg aggagggcta cgagcggatg gacgaggcgc
     1861 agaccgagga gctgagccga ctggtggtcg agcagcgact gcgccagccg gaagggccca
     1921 ccgtcacctt gtgacctgcg gtcctcgcca caccgccccg gaggggcggg cccggatcgg
     1981 gcccgcccct ccggcgttcc cacgtccact catttccgta cccggagttc ccgcactccg
     2041 ggtatttcca tgtccgggtg tttccactct ccggacgttt ccgtgtccgg gtgtttccgt
     2101 tcatgtccgc ctgctgctgc ggcggcgttc tgttccccgc cgtcgcctct ccctcggcac
     2161 ccccgcgggg ctctgctact gcaaacggcc cggcggccgg agcgcgtcgc aattccctcc
     2221 ccgtcccgtt ctaaacaccc ggagtgtaca taggtggaca cgaactcgtc ggaaatctct
     2281 ggatagggtc gtgggtaatt gaggtgactg cgggttctcc ggtgcacgga gccggaaatg
     2341 ggcgacgagg agtcggcgaa ttatttcgtc ggcaaggctt cccaggattg cctgggatac
     2401 cgggcggctg tcggccggtc ctggctcgga caggatccgg tcagtggttt tcgtcgcgtg
     2461 gaattccgcg gaaacccggg cgggacatcc gcttcgcgac cggtggtgcc ggtgcgatgt
     2521 atgtgtgcgc ggtgcccggt gacggcatcg gccgatggcg aaggaggttg tgcatgccgg
     2581 tgaggcacga ggacaagggc cgggcggcgg tggtgacggg tgtcggcggg tgggtgcctc
     2641 cggacgtcgt caccaacgac gacctgtccg cccgtctcga cacgtcggac gagtggatcc
     2701 gtacccgtac cggcatcaga acccggcatg tgatctctcc cggtatggcc acgtcggatc
     2761 tcgccttcga ggcgggccgc agggccctgg aatccgcggg cgacccggag gtggaggcgg
     2821 tcgtgctcgc cacgaccacc cccgaccggc tctgcccggc caccgcgccg gaggtcgccg
     2881 cccgtctcgg gctcgtgggt gtgccggcct tcgacatctc ggcggtctgc gccggtttcc
     2941 tctacggcct ggcgacggcg gcggggctga tcgcctcggg gtcggcacgg caggttctgc
     3001 tgatcggcgc ggacgccttc accaccatcg tcgaccccaa ggaccgtgcc acggcggtga
     3061 tcttcgcgga cggggccggt gccgtggtgc tgcgggcggg ccgggccgac gagcccggtg
     3121 cggtgggccc tgtgatcctc ggcagcgacg gcaggttcgc ggacctcatc caggtgccgg
     3181 ccggcggttc acgccagcgc tcccacagcc ggtcctgcgg cccgggtgaa gagttcttcc
     3241 ggatggacgg acgcggcacg ttccggcagg ccgtggagcg gatgtcgacg gcgtcccggc
     3301 aggcggtcga ggccgccggc tggcgcgtgg aggacgtcga ccggctcgcc gcccaccagg
     3361 ccaacgcccg gatcctcaaa gccgtcgcgg acgagctggc cgtaccggcc ggacgccagt
     3421 tgtcgaacat ctcccgggtc gggaacaccg gcgccgcctc catcccgctg ctgctcgccc
     3481 aggcagccgg ggacgggagt ctcgccgagg gacaccggac cctgctcacc gccttcggcg
     3541 gcggactgtc ctggggcgcg gccacgctca cctggccggc gctccccacc gcctgacgtc
     3601 aactctcccc cccccacaaa ggaatctgcc ccccatgttc gagacgctca aagaagtact
     3661 ggtcgacaaa ctcgaagcgg atcccgagga gatcactccg gaggccaccg tcgaggacgc
     3721 cggactggac tcgctgtcca tcgtcgaact ctccatcatc ctggagaagg accacgcgat
     3781 cgcgatcacc gacgacgagc tgctggccgc tcccacgatc ggcgacatgg cgagactgat
     3841 ggaggagagg aacgcggcgc tctgacgccg gtacggcggt gtagtcggga cggcgatacg
     3901 gcggtagccg gtacggcggt acgggcgcgg gaagacccct gccgtacggg cgcaccgcga
     3961 aaagcggcgc cggtcgcccc ggtgtcctga gccgcccacc accgcaggcg gcgggccgcg
     4021 gggcgacccg ctccgtcccg ccgcccgcgt gaccccacgg cccgttcgcc gggactcccc
     4081 ggcggccccg gtgtgagtac gccgccggcg cccccggtcc gcgagaaccc tcaggtccgc
     4141 gagcccccgg tcgtccgcga taaaccccca ggtccgcgag aaccctcggg cggggccgtg
     4201 tcgcccctca cacttttccc cgcccgagtc gcccgttccg ccggtgctgt tcgaccggcc
     4261 gaatgggcgg cgagaattgc ggaaccctcg attcccctcc cctcccgttc taaacacccg
     4321 gagtgtacat aggtggacac gaagtgcttg aaaatctctg agtagggtca tgtgtaattg
     4381 gcctgtcgat aggcgtcgtc cttcgtatgc ggagtccgga gtgagtgaaa gtaaaacggt
     4441 taaccttttt catcggcccg gttttccgag cttcttggaa gggatctatc aaggccggtt
     4501 cgaatgggac gtgataagtg atttcgttgc gcaggattcc gccgacgaaa aggcggggga
     4561 cgcggtggtg gaacgcctgg cggatatcct cagggaccgg gtgaacccca ccgccgtcga
     4621 cgccacccgg gagctcccgg aagggctgct ggaggaactg cgccgcgacg ggttcctgaa
     4681 tctccaggac tccccggacg tcggcggcct gggtctctcc gcctacaaca ccttccgggt
     4741 cgtccaggcg gcggcgagct ggtcggtacc ggtcgcgctg gtcctcggca tccagacggc
     4801 cgtcggttcc ggaacgtacc tgcgggcgct gccgcccggt gacctgtact cctacgtcga
     4861 acagcggctg ctggacggca tcatctccgg ttccgccgac acggagcccg ccggcgcctc
     4921 gaacagcgcc cggcagaccc gcgccgtccc caccgacgat ggagaaacgt ttctccttac
     4981 cggtgagaag atccatatcg gcaacggccc gatcgcggac gtcgtgaccg tctcggcgat
     5041 gctggacgag gacgggcagg accggccccg gctgttcttc gtggagacct ccgacccggg
     5101 gttccgtatc cgttcccgcc acgagttcat gggggtcaag ggcttcccca acgcggcact
     5161 ggtcctggac ggcgtccggg taccgcgcgc acgcatgatc gtcgaggtcg acccggagac
     5221 cgaggtgcgc atcaccccgg aactcaccat ggccgtggtc cggggccggc tgcatctgat
     5281 caccgccccc ggactcgcca tctccaaact ctgcctggaa tggtcccgga acttcctcaa
     5341 ccggcgtacg gtcgacggcc gtccactggg ggaccgggag gaaatccagc acatggtgtc
     5401 ctccaccatg gccgatgtct tcgccatcca ggcgctcgcc gaatggagtc tgctccccgc
     5461 ggaccaaccc ggcctcggca tcaatgtggc attcgaacag aacgtcacca aggcgatcag
     5521 cgcggagatc tgctggcggg tcgccgaccg caccatggac ctgctcgccg gagaaggctt
     5581 cgagacggcg cccagcaaag cgcggcgcgg cgtgccggcc cttcctctgg aacgcttcta
     5641 ccgggacgcc agaaacctcc ggatatccgg cggggtttcc ttcctcctcc aattctgggc
     5701 cgcccgcatg agccagttca cgtattacgg accggaccgc gcccggccga cggacgcgcc
     5761 cccgccggat ccgggccggc cggccgctcc cgtacaggag ccgcgtgccg acggcctcga
     5821 ccccgtgaac gccgggcatc tgcgcttcgc cgccgccgaa acccggcgcc tcggcgcctc
     5881 ctgcgaggag ttcgccgccg accaccccgc gcccgggctc ttcgaccatc agcaccgcct
     5941 catcgcctac agccggatcg ccgacgagat cctgaccatg tcggtcgtgc tggcccgggc
     6001 ggcccgcctg caccgcgagg gcggcaccgg ggcccaggac ctcgcccaca tctactgcgc
     6061 gcgggccagg gaccggctcg ccgggctgtg gcggcaggcc gagcccgaga cggccggccc
     6121 cggccacgcg gccgtgagcg acgcctggct cggcggcgac gaccggtacg cctccctcac
     6181 cgacggcgtg atcaccgaca taccgcccac cgccgacacc cacccggggg agcgatgaag
     6241 aaggacaaga accgcagcgg ggcgagcgca ccgcgcgaag cctccccggt cgcctcgtcc
     6301 ccgaccgagg cagcgaccga ggcagctacc gcccccgccc gcgggctccc gctctccgtc
     6361 gaccagcagg ccatctgggt gcactggcag gtcgacccgg accggaccag ccacatcctc
     6421 cacatgccgc tgctggccga ggagggcgag ctcgacctcg tacgggtccg ggcggcgacc
     6481 agggcggtcg gggaacgctt cccgatgctc cgcgccaggg tcgtggagag cggcgaggaa
     6541 gccgcactgc tgtgggacga cgcccccggc atcccggtca ccgaggtacg gacggaccgc
     6601 ccgcgcgccg agacggtcgc ccaccacggc gcgttcccct tcgacctgcg ccaggggccg
     6661 ctggcccggg tccaggtgct gcacggaccc gacggcacgg tcctgctcat cgacgtccac
     6721 cacctggtct tcgacggagc cgcctgcggg ccgttcctgg ccgccttccg ggacgcctac
     6781 gcgggcaagg acctcggccc cgccgacgac accacggccc acgccgagtt cgcccgccgc
     6841 cagcacgaac tgacccacgg cccccagggc gacacgcacc gggaacactg gcgccgcacc
     6901 ctcggcgagg acctgcccga cccgctccgg atgccgggcc gccccggcga acccgccttc
     6961 cacgaggccg tcctcgaccc ggatctgctc gccgccgccc gcaccgcggc cgccgccgcc
     7021 cgggtgcatc cgatgatccc gctgtacgcg gccttctgcc tgctcctgcg tgcccgtacc
     7081 ggccaggatg acctgatcgt ccccacgccg taccacggca ggtcccgcga actgggcgaa
     7141 cgcgtcggct acttctccaa cgtgctgccg ctgcgccacc ggctgcccgc cggtgtcagc
     7201 caccgccgga tcctgcgcga cctgcaccac accctgcgcg agggcgtccg gcacggtgcc
     7261 ctgccctacc ccgctctgct gcgtgccgcg ggtctcaccg ggcagctcgc ccgcacccac
     7321 gccggacagg tcaacttcca gtactggccc gcccctcccg gggacatcga cctgaccgcc
     7381 atcgcactgg acagcccgga cagtccgggc ggcaccgcgg tgctgcggct gctggcgatg
     7441 gaggactacg ccgaccacac gctcaccgtg atgctgcggg aggacccccg cggctccagc
     7501 ctgatctgga aggaccccac cggggccgtc ggacgcgcca ccgtggagga actggccgcc
     7561 gcctacccgg tggtgctggc cgcgctgatc gcggacctcg acgccacgct cggcgaaccc
     7621 gtcccggaag ccgccgtagc ccttgaccgg ccgtcgcccg aggcgtcgcc gatggacgag
     7681 cgggcgtgga acacgggcac cgacgccggc ttccccgacg tgtccctgcc cgggctgctg
     7741 cgcacccgcg ccaccgccac cccggacgcc gtcgccctct cgcacggcgc gcggcggctg
     7801 acctacgccg agctgaccga ccgcgccgcc accctcgccc ggggactcgc cgcccggggg
     7861 gtgcgccccg gcgacctggt cgcactcctg ctgccgcgcg gtgtcgccca ggtggaagcg
     7921 gtcctcgcca ccctgttcgc cggagcggtg tacgtaccgc tggacgtggc ggtgcccgcc
     7981 gagcgccacc ggctgatcct tgaggacagc caggcggtct gcctggtcac cgacgggcgg
     8041 cgcggcgtcc ccggcttcac cggtccggtg atcgcactgg acgagctgcg ggacgtaccc
     8101 gagggggacc tgccggagac cgaccccggc tctcccgcct acgtgatctt cacctccggc
     8161 accaccggac gccccaaggg tgtggtgatc acccaccgca acgtggtgcg gctcgtggtc
     8221 aacgacaagc tgccctacac cttcggcccc ggcgatgtgt ggacgatgtt ccactcctac
     8281 gccttcgacg tctccgtctg ggagatgttc ggctgcttcg cccacggcgg acgactggtg
     8341 gtggtgggca gcgacgaggc ccaggacccg cagcgcctcc tcgccctgct gcgctccgag
     8401 aacgtcacgg tgctcagcca gacccccagc gccttcgccc agctcaccgg cgtgcacacg
     8461 agcggacagg acccgctgga cgccctgcgc tacgtgatct tcgcgggcga gaaactcgac
     8521 ccgggatccc tcgccgggtt cgcggcccgc cacccgcgca cggccctggt caacatgtac
     8581 gggatcaccg aggtcaccgt ccacaccacc ttccgcgagg tcaccgcgca ggacatcggg
     8641 accggccgca gcaacatcgg cgaacccctg ccgacgacca ccctcttcat cctcggcccc
     8701 gaccgggagc cgctcccggc cggcgagacc ggagagatct gggtgggcgg cctcggcgtc
     8761 gccgtcggct atctcaaccg gcccgaactc accgccgagc gcttcctccc caacccgttc
     8821 ggcgagggaa ccctgtaccg cagcggcgac ctggcccgcc gcctgcccga cggcaccgtc
     8881 gaatacgtcg gacgggccga ccagcaggtc aagatacgcg gctaccggat cgaacccggc
     8941 gagatcgaga accggctcct cgaacacccg gccgtcgagg gcgccgtcgt gctggccgag
     9001 gccggacccg gcggcgaggc gcgactcgtc gcctacctgc tgccgcacgg caccccgccc
     9061 accaccgctt ccctccggac cgcttccctc cggggccacc tcgcggcgcg ccttcccgcc
     9121 tacatggtcc cggcacggtt cctcaccgtg gcggccttcc ccctgacggt caacgggaag
     9181 accgacacca agcggctgcg ggagaccgga acaccgctgg agaccggcca ggacaccgac
     9241 ccgccgcgca ccgcgaccgc ccgcgccgtg gccgaggtct ggtcggatct gctgaaggtc
     9301 cgcgatccgg gcgccggcca gtccttcttc gaactcggcg gccactccct gctcgccgcc
     9361 cgcaccctgc gggagaccgc cgaacgcctc ggcgggcccg taccgccgct gcggacgctc
     9421 ttcgaccacc cggtgctcca ggacttcgcc gacgccctcg accggctcac ggaccggccc
     9481 gggcccgcac cggcccccgc acccgtccgg accgggggac cgctgcccgc ctccggcttc
     9541 cagcagcgga tctggttcga cgagcagttc ctcgaaggcg gagccctcta ccaggtgccc
     9601 atggtgtggc gggtccgcgg acgcctggac ccggccgtcc tgcgcacggc actgcaccgg
     9661 atgaccgaac gcaacgagat cctcaggacc gccttcgtcc agcgggacgg cgccctgtgg
     9721 caggaacccg gcgccccctg gcagccggag gtcgaccacc aggacctgac cacgaccacc
     9781 ggccacgacc gcgaccacag ccagaaccag aaccaggacc acgaccggga ggtgaccgag
     9841 cggctgcggg ccgccgcccg gcagcccgtc gacccggcct ccggcaggct cctgcgcatc
     9901 accctgttcg acctgccagg ggaggaacag ctcctcctcc tcaacaccca ccacctggtc
     9961 tgggacggcg gctccgcaca gcccttcctg tgcgaactcg ccgactgcta cgcccaggcg
    10021 ctcgaccccc acgcgccgcc gcccgcgccc cgaccccagt tccgggacgc gctgagcggc
    10081 cgggccgccg ccgacgtctc caccggtctc ggacactggg ccgcccggct ggacggcgcc
    10141 cccgcccacc ccgccttcga accgcccgcc accccgggcc cccacggcag ggtccccgtc
    10201 ccgctccccg ccgaactgcc ccaactcctc ggagaactgg ggacacaaca cggggtgagc
    10261 ccggccatgg tcttcgccgc cgcgctcgcc gccgccctgc acggctggac cggccaggac
    10321 gacgtgacct tcggaacccc ggtcgccgga cggaccgacg aggaacacgc cgaggtcatc
    10381 ggaccgctgc tgaacaccgc cgtcctgcgc tccaccaccc accgggggga gaccctcggc
    10441 gagctgctcg gccggctgcg cgacaccgtc ctcgacgcga tcgaccacca ggacgtcccc
    10501 ttcgaggacg tggtggagcg cctcaaccca ccgcgcctgc ccggccggag cccctacgtc
    10561 gaggtcatgc tcgcggtgga gtccgagccg ccggccccga tgctggtggg ccccggccag
    10621 atgaccccgt acctcttcga ggacccggag acggacgcgc acgccaagtt cgccctgacc
    10681 atcgacttcc gcgaacagga cggccggttc accggacacc tcgcccaccg cggcgaccgg
    10741 atctccgccg aggtggcccg ggccttcgcg ggcctgctgg gccgcacggt cgaagcgctc
    10801 tgcggcccgc ggacccagcg cgtggacgag gtgccgacgg ccggccccgg ggaactcgcc
    10861 cggatcaccg ccttcgagaa gggcgcaccg gcccacccgg ccaccaccct gcccgccctg
    10921 ctcgccgaac ggatctccca gcggcccggc gcacccgccg tcgagtcctc ccggggcgtc
    10981 ctccactacg gcgaactgca cacacgggcc ctgcggttgt ccgcccgtat ccgcaccgcc
    11041 gttcaggacc gcgaaccgat tgtggccgtg gtcctgggcc gcggccccga cctggtgacg
    11101 gccatgctcg ccacctggta cgccgggtgc gcgttctgcc cgatcgaccc ggactacccg
    11161 gacgaacgcg tccggctgac cctcaaggac gtcgccgccg gagccgtcgt cacggagccg
    11221 ggccggtcct ccgccaccgg cgacgtcccg gtcctggaag tcggcgaccc gtccgcgtac
    11281 ccgggggacg gcccgctgcc cgagccgcac acgcccaccc ccgagagccc cgcctatgtg
    11341 ctctacacct cggggacgac cggacggccc aagggagcgg tcctcagcca ccacggcctg
    11401 gcccagctcg cgctgtggca catggaggcg tacgacatca cgcccgagga ccgggcgagt
    11461 catctgtcca gtgtgggctt cgacgccacc cagtgggaga tctggcccta tctggccgcc
    11521 ggagcctgtg tggtcgccca tgaccggcgt gtcgtggtgc ccgaactggc gccgtggctc
    11581 gccaagcacc gcatcaccat gacctatctg tccaccccgg tcgccgaagc ggtgtggggc
    11641 accggagcgg acctccccgc gctgcgctgg atgctgttcg ccgccgccgc ccagacccgg
    11701 cgcccgcccg ccgacctcgg ctaccgggtc gccaacaact acgggcccac cgaaggcagc
    11761 gtcgtcgcca cctggcagcc gggaccgatg ccccaggacg ccccgctgaa cgtcgtcggc
    11821 cgcccgatca ccggcaaatc ggtgtacgtg gtggacccgg ccgggcgccg ctgcccgatc
    11881 ggggtgaccg gcgaactcct catcggcggg gtcggtatcg ccctggagta ccggggcaac
    11941 ccggagctga cccgggagcg gttcctgccg gccggccccg gcggagcccc cggccccgtc
    12001 taccggaccg gtgaccgggc ccgctggcgg gaggacggca ccctggagtt cctcggccgt
    12061 gtcgaccgcc agctcaaggt acgcggccac cgcatcgaac cccaggaggt cgaggcggga
    12121 ctcctcgccg acccccgggt cctgcgggcc tatgtgtccg gggacgcgac gaccctggtc
    12181 gcccatgtgg tgcccgccgc cccggacgcc cgggacagcc ggcgtgtcct ggacacgctc
    12241 gccgcccgcc tgccggccca tctggtgccc gacgccctga tgtggctcga cgaactgccc
    12301 acgaccgccc acggaaaggt cgacgtcgcc cggctgcccc ggcccggccg cgacgacctg
    12361 gcgggcaccc agagctgggt ggagcccgcc gaccgcctgg aacagcggat cgccgccgtc
    12421 tgggccaccg tcctggacct cgaacgggtc ggcgccgccg acaacttctt cgacctgggc
    12481 ggcaactccc tgaaactcgc caccctccat gcccgcctgc tgaaggaact ggaccgggag
    12541 atccccgtac accggctctt cgaattcccg acggtacgcc ggctcgcccg cttcctcgcc
    12601 ccggaggacg acggccccgc cacgccctca ccggccgccc gcgacgacat cgacgcacgg
    12661 gccgcccgct ggcgaacccc cgcaccgcgg cagtcgcccg ccgcccatgg aactccccgg
    12721 aggaaccgca actcatgacg accaatcagc agatcgcggt catcggcatg gccgcccgca
    12781 tgcccgggtc caccggcatc cccggattct gggcggacct gcgggcgggc cgggaaggac
    12841 tgacccgctt cactaccgag cagtccctcg ccgccggggt ggaccccgca ctgagccggc
    12901 accccaacta catacccgta cgcggcacca tcgacggcgg cgaccggttc gaccactcct
    12961 tcttcggcta cagcccggcc gaggccgcca ccatcgaccc gcagcagcgc gtcttcctgg
    13021 aagtggcctc caccgccctc gacgacgccg gtatcgaccc ggcccggctc aacggctgga
    13081 tcggcgtcta cgccggaagc gacatcaccc ccgaccgcac ccccggcgaa ggggaactgc
    13141 tgagccaggt gatcggcgcg gagaaggact tcgtcgccac cagggtcgcg tacaagctcg
    13201 gactgcgcgg ccccgcgctg gccgtccaga ccgcctgctc cacctccctg gtcgccgtcc
    13261 accaggcatg caacgccctt ctgtcccacg actgcgacgt ggccctggcc ggcggtgtgt
    13321 ccctgcgcct gccccagtgg acggggtacc agtacagcga gggccacatc atgtcccgcg
    13381 acggacactg ccgccccttc gacgccgacg gctccggcac cgtccccagc agcggggccg
    13441 gcgtggtcgc cctgcgccgc ctggaggacg cgctggccag cggggaccgc gtcctcgcgg
    13501 tgatccgcgg ctgggcgctc aacaacgacg gcggcagcaa ggtcggctac accgccccct
    13561 cggtcaccgg gcagcgcgac gtcatcaggc tggccctggc ccgggccggc gccgaccccg
    13621 ccgacatcgg ctgcgtcgag gcgcacggca ccgccaccag gatcggcgac ccgatcgaga
    13681 tggccgcact cacctcggcg ttccgggaca gcaccgacca tgtgggcacc acctggctcg
    13741 gcgcggtgaa gagcaacatc ggccacaccg gggccgccgc cggcgtcgcc ggactgatca
    13801 agaccgtgct ccagctccac caccgcgaga tcgccccgac cgtgcactac cggtcgccca
    13861 accccgccct caacctggcg gagagcccct tcaggatcgc caccgaggta cagccctggg
    13921 acaccgaagg gccgctgctc gccggcgtca gctccttcgg tatcggcggc accaacgccc
    13981 atgtggtcct ggagagcgcg ccacgcctca cccggaccgc ccagaccgcc cggccccgcg
    14041 tcttcccgct ctccgcgcac agcccctggg cgctggagaa gctgcgcacc tcggtcgccg
    14101 acgcgctcac cgccccggcc ccgggctcca cctccgcccc cgcctccacc ttcgttcccg
    14161 cctccgcctc cgcctccgac gacgggaccg aagacaggct cggtgacgtg gccttcaccc
    14221 tcgccgaagg acgccgcagg ctcccgtacc gcacggcggt cgtcgccggt gaccgggaga
    14281 gcctcgccgc cgccctgcgc gcccccgccg acccggtcga gcaccgcggc gccacccccg
    14341 ccgtcgcctt cgtcttcccc ggccacggca ccctccacca gggcgccgga gccgccgccc
    14401 accggctgct gcccgagttc cgcagggtct tcgacgaagc cgccctgatc gtcagggagc
    14461 ggtacggcct cgacctgagc gccctggtca ccggccagga cgcccccgtc gaggagatca
    14521 ccttccagca actcgccctg ttcaccctcg gctacgcgct cggccgccag ttgcgtgtct
    14581 ggggagtgcg gcccgcgtcg atgatgggca acagcgtcgg cgagtacgtc gtcgccgccc
    14641 tcgccggggt ctggaacctg gaggacgccc tgtccctggt ccatctgcgg ggccggggga
    14701 tgctgtccgc cgcccccggc cggatggtcg ccgtcgtccg caggcccggc agggaactcg
    14761 cgatacccga cggcgtcacc ctcgccatcg acgccccgca ccaactcgtg ctctccggcg
    14821 aggcggaacc ggtgatgaag gcgcaccgga cctgggaggc cgagggctgg tcctgccgga
    14881 tcctggagat cgaccgcgcc tcgcactccc cgatgatgga cgcgcccgcc gcggaactgc
    14941 gggccgtcgc cgccaccacc cccacgggcg gcacggacct cggggacacc gtcgtcgtct
    15001 ccaccctcac cggcgaagcg gtcgaacccg ggcatctcac cgaccccgga cactggggcg
    15061 accatctgcg cggcaccgtc cagctccggc gcgccatcgg caccctcctg gacgcccccc
    15121 acgacctcgt cgtcgaactc ggccccgggc agagcacgtt gcgcggactg cggatgcacc
    15181 ccgactggaa caccgccacc ccggcgatcc ccgcgctggg ccgctccgcc gaccaggaga
    15241 ccgagagcgt cctcgaactc tgcgccaccc tctgggagca cggcgtcgcg gtcgacctgg
    15301 ccggactcct cgacgccgac gagccgtcca tcaccgaact gcccgcccac ccctacgagc
    15361 ccaagcccct cccggcccgc cccaccaccg ctaccgccgc cgcgccggag gcgcccggac
    15421 accccgagcc cgccgctctc gccgcgccgg agacgcaccc gaccctcacc accgacgcct
    15481 ggacctccat ctcccggcgc ctgtccgcgc acagcgccgc cgcggtcggc gagcgcctcg
    15541 ccgccgaact gggcctgccg gccaccgacg accggttcac cgggctcacc gcctccgtcg
    15601 tcgtcgccga actgccggac gacgacgacc gggccgcacc gagcgccctc gccgaccggg
    15661 cccgtaccgc cggagtccag ctcctgctgc tgggccgcga agtcttcgac gtcctggacg
    15721 acagcatcga agcggccgcc ctcccctcgc cggccgccga gtggctcggc caccgggaga
    15781 ccgccggcga ccggaccacc ctcctcgaca tcggccccgc cggacgcccg gactggctcc
    15841 ccgccccgtg gccgggcgcc acccgctacg cctggcgcgg cagcggctgg tgggcgctgc
    15901 tgccccggcc cgtccccgtc gagccggtga ccgacgcccc ccgggtggcc ctggtcaccg
    15961 acgaccccga cgccaccgtg ctcgccgccg acctcgccgc ggccggcgtc cacgtcgcct
    16021 ccctgaccgg cgacggccct ccgcccgccc ggccgacggc cggcacgatc gccgccaccc
    16081 agacctggcg ggccggatcg gcccggctct cccagcggcc cgagctgaac acccgcgtcg
    16141 accgctacag cgccggtctc atcgcccgct tcgccctgga gcgcgccgga ctgcgccccg
    16201 gcgaccggat cgccgcgtcc gagctgcgcc accggctcaa ccccggtgaa cggctgaccc
    16261 gtttcttcga cttcctgctg cgctccctcg tcgaggagga cgtcctgcgg cccggacagg
    16321 tggacggcgc cgacggctac ctcgtcgccg ccggccccca ggacctgctc gcggccggcg
    16381 cagggctcgg cgaggtggac ggcctgcacc ggctgctcga cagcatcgcc gccgaactgc
    16441 ccgcggtctt cgacggcgag aaggaaccgg tcgccgtgct ctggcccgac ggcgacgaca
    16501 gcatgctgcg ctcctggctg ccggacaacc ggctggagat ctacgacgga gggttctgcc
    16561 tcgacgccct ggaggagacg gtacgttccc tccaccggac ctggggcgac cgcccgctgc
    16621 gcatcctgga ggtcggcggc gggcacggtc tgttcacctg gcagctcctc gaaggctggc
    16681 aggaccggga caacgtcgac taccacttca ccgacatcag caccctgctg gtgcgcaggg
    16741 ccgccaagta cgcccgtacc aacggtgtcc gcggagtgcg cttctccacc tacgacatga
    16801 cccgcgaccc ggtggaacag ggcctcgccg cgggcagctt cgacctggtc atcgcgtaca
    16861 acgtcatcca cgtcgcgccc tcggtgcaca cggccctggg acatctgcgc agcctgctct
    16921 ccccgtccgg cgcggtctcc ctcgtggagg tcaccgacgt cacccggtgg agccatctgc
    16981 tgtggggtct ggcaccgggc tggtgggact tcgacgacga actgcgcagc gactcgatcg
    17041 tcctggacgc ggcgacctgg cggcgggcgc tcgcggagtc ggggctcccg gagatcaccg
    17101 tggtcccgga cggcgtcccc tcggaccaca ccctgatgat cgcggcgccg tcccgcgcga
    17161 cggacggggc ccccgccgca ccgccgttcc cggacgtcga cctggtgctg tccgtgctgc
    17221 gctcgcccga cgagcggacg gcacacgagg ccaccgcccg ctggaagtcc ctacggtccg
    17281 aagggccgct cgcggccacc ccgggcgtgc tgctgagcac cggcccgctg gacggggcga
    17341 cccgcgctct gctggactcc ccggcggacg cggactggac acatctgcac gccgaccgct
    17401 tcggtgcggc ggtgctcgac gcgctgcccg aggtactggg ccagccctgg ctgccgcgta
    17461 cggtccggct gcgggcaccg gagatcccgg acaccgtgcc ggcctccgcc gcccccgcgc
    17521 ccatggcccc ggcggacgtc ccggagaccc tgcgccccgc ggcggccccc gcccccgcgg
    17581 gcccggacgc ccgcctcgaa caagccctgc ctgccgcacc ggccgctccg gccgccgctc
    17641 cggtggccga accggtggcg ccggttccgg ccgtcgccgg cccgagcggc gccctcgccg
    17701 ccctggacga gctgtggcgt tacgaactgg gcgtgccgcg ctcccgggcc gaggacgact
    17761 tcttcgccct cggcggcgag tcgctcgccg cggtccacct gctggcccgg gtgcgggacg
    17821 tgtgcgggat caaggtgccg atgtccgact tcacccgcga ccccacctac gggttcctgg
    17881 cgggcctggt cggctccgta ccgcagccgc gacagcaggc acagtccgag ccgcagccgc
    17941 agcaacacac acagcaccag caacacgcac agcaccagca gcacgcacag ccacagcaac
    18001 aggcacaggc acagcagcag tcgcagcgcc gggccgggac gcggacacca gccgacagcc
    18061 cgaacctcat gacgctgaac gacgccggtg agggcacccc gctcttcctc tcggccccgg
    18121 ctgcgggcag cgcgctgtgc taccgcggac tcgccaagca cctcggcgac cgccccctct
    18181 acggcctgga gaccccaggt ctgcacgacg gacgcgcgcc gctgagtcgg ctggaagaca
    18241 tcgcgaacca ccatgtcgag ctgatccgga gcatccaacc ggacggcccg tacctgctcg
    18301 gcggatggtc gttcggcatg atgctcagcc acgagatcgc ccgtcagatc atcgccgacg
    18361 gcggggcagt ggccctgctg tcgggtgtgg acggctatct cccgaacacc ggtggaatgc
    18421 ccatggtcac ccagcccggc ttcctcctcg gcggcctggt ctacaagacc caggcggtgc
    18481 tcggactcgg cggcgcgcag ccggcgggag cgaacggacc ggagccggac gaccggatcc
    18541 tgcggatcgc ggacgtgacg cgctggcgca ggcagcgcgc cagggccgga cggcaggaga
    18601 agacggccgc cgacttcgtc tccgtgcaca accacagcat cgacgcgatg ttccgctacg
    18661 tcccccagcc cgtgaactgc cccgccgtga tcctcaaggc cgggctgaac gagcgcggcc
    18721 ggctacggct ggaacgcggg ctgcgcggcc tctacaccgc cgtggaggtc cgctcggtcg
    18781 ccggtgacca ctggaccgtg atggaccgcc gcaacgcccc gggtctcgcc acacagctca
    18841 accaggcgct gcggcagcac gaccccctga cacaggaaga gaaccactga tggtgacgat
    18901 cgacccgaac acgttcaaca ccgacccctt cccactgctg caccgcctcc gggaggaagc
    18961 cccggtgcac caggtcgagg ttctggacgg tctgggccgg ccccgctggc tgatcacccg
    19021 gtacgaggac gcgctcaagg cgctcaacga cctgcggttc agcaacgagc tgttcgccgg
    19081 catgggcccg gccgacgacg cgggggaggc ggagccgagc ctggtcgcac aggcgatcaa
    19141 gaaggccgag gccgtgcagg gccgggcgat ggccaacctc gacccgccgg accacacccg
    19201 gctgcgcaag ctggtcgtca gatcgttcag cgccaagcgc atggaggccc tgcggcccca
    19261 ggtccaggag gtcaccgacg ccctgctgga cacggtggcc gggcaggacg agttcgacct
    19321 cctggagacg ctcgcctacc ccctctcgat ccgtatggtg tgcaccctgc tgggcgtgcc
    19381 ggcggacggc gtcgacgtgt tccgcggcgc cgccgcggtc ctcgcgggct tcatgaacga
    19441 cgacgactgg gcccgggaga ccctccggag cctggaggga ttcgacgtct acgtacggca
    19501 gttggtggcc gacaagcgcg acgatccccg cgacgacatg ctcagcgacc tcatccactc
    19561 caccgaggaa ggcggcaggc tcacggagga ggagctggtc gcgatggccg gcctgatgat
    19621 cttcgccggg cacgagacca ccgtccagct catcaccaac gcggtcctcg ccctgcacca
    19681 gaacccccgt cagatggccg ccctgcgcgc cgatcacggg ctgctgtccg ccatgaccga
    19741 cgaggtgatg cgctacgacg ggccgatcaa cccgggcatc aacagggtgg cccgggagga
    19801 catcgagatc ggcggggtga ccatccccaa gggcgcctcc gtcgtcatcg ccaccgccgc
    19861 agccaaccgc gacccgcggg cgttcaccga cccggaccgc ttcgacatca cccgctcgcc
    19921 cgacaccgtc catctgggct tcggccacgg catccactac tgcctcggag ccaggctggc
    19981 caagatcgag gcggagtgcg ccatcgggac cctgctgcgc cgctacccgc gcatcgccct
    20041 cgccacggag ccggagaacc tgcggtggcg ccccggattc ctccgtatgg cggaggagtt
    20101 ccggatccgg gtcgacgccc cgtccccgcc ggcggacgtg ccggcccatt ccccccaccg
    20161 agcaggagag aacgcccatg tctgacagcg gctccgcgag ccacgcgctc gtcgagaaca
    20221 ccgagggcga cctcggcgtc tggcccgtga cccgtccggt cccaccgggc tggcggccgg
    20281 ccggccatca gggcagccac acctcctgcc tgacggaggc cgaccggcgc ggccgcgaac
    20341 gacccgcggg cgcccccacc ccgccggagg gcgacgcggg caccctgctg gaactcttcc
    20401 gccgtacggt cgagaaccac ccggccaggc ccgcggtctc cgaccgcgaa cacacctaca
    20461 cgtacaccgc gctcaaccgg cactccgacg ggctcgccca ggcgctcctc gcccgcggcg
    20521 tccgccccgg cgaccacatc gcctacctgc tgccccgcgg cgtcgccccg ttcgtcgtcc
    20581 tgctggccac tctcaaggcc ggggccgcgt acgtaccgct ggatccgacg gcccccgacg
    20641 accggctgcg cctgctgatc gaccacagcg gcgccaccac ggtgatcacc cacccggaga
    20701 tggccggccg gctggacggc ctggccacgg cacggctcat ggagtacgcg ccgggcgacc
    20761 acgccgatcc caagccgggc cccgccaccg cggccgcacc ccggcagggc gcgagcgtcc
    20821 tgttcacctc cggatccacc ggagtgccga aggcggtgct cctggaacac cgcaacctgg
    20881 cccagttcgc cgagaacccg gcgctgcccg ccctcacccc gcaggaccgg atcggccacg
    20941 tctccaacct cgccttcgac gccttccact gggagacctg gtgcgccttc gccgcgggcg
    21001 ccgaggtggt caccctgccc accatgcccg acctgatcgg cggcgacatg cggcgcgaac
    21061 tgaaacagcg ccggatcacc gccatgctcg tccccaccct ggccttcaac cacctggccc
    21121 atgagcagcc ggagaccttc tcctcgctgc ggatcctcgc caccggcggc gacgtggtgt
    21181 caccgggcgc ctgccgcgac ctgctcgcgg cgggcttcgc cggacaactg gtcaacctct
    21241 acggccccac cgaggcggcc accgcctgct cggcccaccc ggtcaccgac accgatcacc
    21301 acggcagtgt gccgatcggc cgcgccctgg aagggatcgg cctgcacatc ctggacgaaa
    21361 ccctgaccga ggtggcaccg ggttccgtcg gccagctcca catcggggga ccgggcgtgg
    21421 cccgcggcta ccacggccgg ccgggactga cggcggaacg gttccttccc gacccccacg
    21481 gcgctccggg cggccggctc tacgccaccg gggacctggc ggtacggggc gaggacgggc
    21541 tgctgcgcta cgtcggcagg acggacgacc aggtcaaggt acgcggctac cggatcgaac
    21601 cgcgcgaggt cgaacgcgag ctggcccgcc atcaccaggt gcgcgacgtg gccgtggtcg
    21661 tgggcggaga gggcgtcgac cgctacctcg ccgcactcgt ggtgctgtac ggcgacagct
    21721 ccttcgccgc cctgcgcgag gcggccgcct cctcgatgcc cgactacatg gttcccagcg
    21781 ccttcatcag catccccgag atgccctcca acgaccgtgg caagcgggac ctggcacggc
    21841 tccgggagat cgtgacggac caccagaaac accgcgccga ccgggtcgcg ccgagcgatc
    21901 cggtggagat ccggctcgcc gacttctgga aggacctgat ctcggtcgac gaggtgggcc
    21961 tcaccgacga cttcttcgcc ctgggcggca actccctcca ggcgttccgg ctgcgacggc
    22021 gcatcgtcaa ggaactcggc gtggaggtga gcaaccggga gatcctggtg accagtgagc
    22081 tgggggcgct cgccgacctg gtccgttcca aaaccggcct cgtaccctcc cgtaaggagg
    22141 acgatctcgt atgacgactc cgacgatcga cctcaccgac cccgaactgt tcctcggcga
    22201 ggacgccggg ccgatcttcc gtcagttacg gcacaacgac ccggtgcacc ggcaccccct
    22261 ccccgacggc ggcggcttct gggcgctcac caggtacgcg gacgtcgaga cggcgtacaa
    22321 cgaccacacc tcgctcagct ccgagggcgg gcccatgctc ggcggatcgt tccgcagcgc
    22381 cgccgacccg tccgccggcc ggatgctcgt cgcctccgac ctgccccgcc agcgccacat
    22441 ccgccagcag gtgcaccgtg ccttcagcaa cgggatgctg cgacggatcg ccacccaggt
    22501 gaccaccctg gtggacaccg cggtgcgccg cgccgtggcc gacggcggct gcgacttcgc
    22561 caccgacatc gcccccgagc tcccggccgg cgcgatcatg gcgatgatgg gcgtctccca
    22621 caccgaagcc catgagctca tcggcatgac ccgccgcatg atcggcttcc gggacccggt
    22681 cttcgcggac cccggcgagg acgagcggat cgggctcgcg gtggtccagg ccgagatctt
    22741 cgagttcttc gcggagctgc tggcggaccg caggaagaac ccgaaggacg acctcgtcag
    22801 catgctgctg caggcccggc gcaacggacg cccctggccg gaggaggaca tcctcttcaa
    22861 ctgcatgaac gtcgccgtcg gcggtaacga gacctcctcg tacacagcct gtgcgggcat
    22921 cctcgcgctg caccggaacc ccacgcagaa ggcgctcctc caggccgacc cggaactcac
    22981 ggacggcgcg gtcaacgaga tgctccgctg gagctcgacc aacgcctacg tcatgcgcca
    23041 ggccgtccgc gacttcaaga tcggcggccg gctgatccag gacggtgaca ccgtgaccct
    23101 gtggaacgcc tcggcgaact tcgacgagac ccgcttcccc gatccggaca ccttcgacgt
    23161 cacccgtacg ccgaaccggc acctgtcgtt cggcatcggt atccatcgct gcatcggtgc
    23221 gatgctggcc cagatcgaac tcggcatcct ggtacggcac atgaccgaca gccgggtctc
    23281 cttcaccgtc tccggcccgg tacggcgcct gcggtcgaac ttcatccggg gcaccaccag
    23341 cctccccctc accatgacgg ccacgtccgg cccgtagctc cgcacaccag gggccggcag
    23401 ccgccgacgc cggcccctcc ggaacgcccc gacccacctc gcaggagggt cggggcgttt
    23461 ccctgcgagg tgggccgggt ggcgccggat ggcgctggat ggcatcgggt ggcgccttgg
    23521 tggcgctatc cggtgccatt ccgtgcgcct ggacgcgctt gggcatgcgt ggcgccacca
    23581 ttgctcacct aggtgccagt gcgttctcgc aggtcagaat ggtttcggtt ggtgcgacgc
    23641 cgaagaggtg gcatcacggc ttgcgcgtgg cgccactgtg gtgccatgat ggcgtcatgg
    23701 acctcacccc gtatgtcgac accctccgcc gcgaactcgc ggtggccgcc gaagccggcg
    23761 gcgacgaagc ccgcgagctg gccgagaggc tcaccgcccc cctggagtcg gcgacccggt
    23821 tggccatgct caacgtgctc tccgccgcga cggacgagat cacccgcgaa ctcgcccccg
    23881 gttcggtcga cgtacggctg cgcggactcg accccgactt cgtggtgaca ccgccgcccg
    23941 ccgacagtgc tcccgcggcg ccggccgcgc ccgccgaacc gttcaaggcg tcggccccgg
    24001 ccgacggcga cgagggcggc accgcccgcg tcaatctgcg tctgccggcc cacctcaaga
    24061 cccgcgccga ggaggccgcg aaccgcgagg gcctgtcggt caacgcgtgg ctcgtgcggg
    24121 ccgtgtcgtc cgcggtcgac ggcggcaccc ggccgcgtgc gacggagaag acccagacct
    24181 tcggacagag cttcacgggc tgggtgcgct agccgcgccc cacccgtacc acttcaccca
    24241 caccacgtcc caccagcggg gacgccctga agacccaaga ggacgagaca gccatgcctt
    24301 ctttcgacac acccgtaccg atctcggtca ccgcacatgt ggaggccggt tccatccagt
    24361 tcaccgcggg cgaccgcctc gacaccgtcg ccgacgtacg gccccgcgac ccgaagcggg
    24421 accaggacgt acgggcggcc gaccagaccg agatcacgta cgcgagcggc gtactgaccg
    24481 tcaggacgcc caagtccagt atgttcggcc gcaccggcgc cgtcgacgtg acggtcgaac
    24541 tgcccgcggg ttcgcgcatc gacatgaccg gcgcctgggc ccaggtgttc ggcgagggcc
    24601 ggctcggcga ggtccgcgtg aagatctcgt ccggcgacgt ccgcctcgac gccaccggcc
    24661 cgctgaagct gaccgcgtca cacggctcga tcaccgtgga ccgggtcgac ggcacggccg
    24721 agatcaccac cagctccggc agcctgcgcc tcggcctggt cgacggcgcc gccgtcctga
    24781 agaactcgca cggcaccacg accgtcgacg ccgccaccgg cgagctgcgg gtgagcggtg
    24841 ccaacggcga catcgagatc cggcgcgccg aggactcggt caccgccacc accgcccacg
    24901 gtgccctgcg tgtgagcgaa gtggcccacg gcaccgtcca gttggagacc tccttcggcg
    24961 ccatcgaggt cggcgtccgc gagggcacgg ccgcctggct ggatgtcagc tcgggctccg
    25021 gccaggtacg caacacgctc accgtgtccg agaccccgga gcggaccgag gacgccgtca
    25081 agatccgggc ccgcacccgg cacggcaaca tcgacatccg ccgcgccaag gtctga
//
