BGC0000002: aculeximycin biosynthetic gene cluster from Kutzneria albida DSM 43870
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Location: 7,362,971 - 7,504,512 nt. (total: 141,542 nt).
This entry is originally from NCBI GenBank CP007155.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000002
Short description aculeximycin biosynthetic gene cluster from Kutzneria albida DSM 43870
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: CP007155.1
Compounds
  • aculeximycin
Species Kutzneria albida DSM 43870 [taxonomy]
References
Chemical products information
aculeximycin
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C81H144N2O33
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • KALB_6558
  • AHH99917.1
  • acuX1
 7362971 - 7364671 (-) AcuX1
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  • KALB_6559
  • AHH99918.1
  • acuGT8
 7365003 - 7366220 (-) glycosyltransferase
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  • KALB_6560
  • AHH99919.1
  • acuAVIII
 7366235 - 7377376 (-) PKS I
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  • KALB_6561
  • AHH99920.1
  • acuAVII
 7377424 - 7386327 (-) PKS I
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  • KALB_6562
  • AHH99921.1
  • acuAVI
 7386381 - 7409882 (-) PKS I
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  • KALB_6563
  • AHH99922.1
  • acuAV
 7409934 - 7423160 (-) PKS I
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  • KALB_6564
  • AHH99923.1
  • acuAIV
 7423185 - 7432829 (-) PKS I
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  • KALB_6565
  • AHH99924.1
  • acuAIII
 7432850 - 7438114 (-) PKS I
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  • KALB_6566
  • AHH99925.1
  • acuAII
 7438144 - 7453128 (-) PKS I
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  • KALB_6567
  • AHH99926.1
  • acuAI
 7453189 - 7469754 (-) PKS I
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  • KALB_6568
  • AHH99927.1
  • acuO2
 7469967 - 7471178 (-) cytochrome P450 hydroxylase
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  • KALB_6569
  • AHH99928.1
  • acuGT7
 7471171 - 7472406 (-) glycosyltransferase
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  • KALB_6570
  • AHH99929.1
  • acuGT6
 7472403 - 7473617 (-) glycosyltransferase
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  • KALB_6571
  • AHH99930.1
  • acuS6
 7473641 - 7474507 (-) glucose-1-phosphate thymidylyltransferase
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  • KALB_6572
  • AHH99931.1
  • acuW
 7474630 - 7476426 (-) ABC transporter protein
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  • KALB_6573
  • AHH99932.1
  • acuR5
 7476529 - 7477119 (+) TetR family transcription regulator
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  • KALB_6574
  • AHH99933.1
  • acuGT5
 7477412 - 7478632 (+) glycosyltransferase
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  • KALB_6575
  • AHH99934.1
  • acuGT4
 7478919 - 7480109 (-) glycosyltransferase
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  • KALB_6576
  • AHH99935.1
  • acuS5
 7480129 - 7480929 (-) NDP-hexose-4-ketoreductase
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  • KALB_6577
  • AHH99936.1
  • acuH
 7481049 - 7482659 (-) beta-hexosaminidase
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  • KALB_6578
  • AHH99937.1
  • acuN2
 7482946 - 7484181 (+) aminotransferase
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  • KALB_6579
  • AHH99938.1
  • acuGT3
 7484178 - 7485428 (+) antibiotic resistance macrolide glycosyltransferase
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  • KALB_6580
  • AHH99939.1
  • acuN1
 7485514 - 7486623 (+) aminotransferase
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  • KALB_6581
  • AHH99940.1
  • acuGT2
 7486701 - 7487948 (+) glycosyltransferase
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  • KALB_6582
  • AHH99941.1
  • acuS4
 7488259 - 7489725 (-) NDP-hexose 2,3-dehydratase
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  • KALB_6583
  • AHH99942.1
  • acuS3
 7489823 - 7490428 (-) dTDP-4-dehydrorhamnose 3,5-epimerase
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  • KALB_6584
  • AHH99943.1
  • acuGT1
 7490555 - 7491754 (+) glycosyltransferase
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  • KALB_6585
  • AHH99944.1
  • acuS2
 7491783 - 7492757 (+) dTDP-glucose 4,6-dehydratase
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  • KALB_6586
  • AHH99945.1
  • acuR4
 7492823 - 7493563 (-) LuxR-family transcription regulator
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  • KALB_6587
  • AHH99946.1
  • acuO1
 7494079 - 7494945 (+) F420 monooxygenase
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  • KALB_6588
  • AHH99947.1
  • acuS1
 7495132 - 7496334 (-) NDP-hexose-C3-methyltransferase
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  • KALB_6589
  • AHH99948.1
  • acuR3
 7496448 - 7499231 (-) LuxR-family transcription regulator
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  • KALB_6590
  • AHH99949.1
  • acuR2
 7499231 - 7501849 (-) LuxR-family transcription regulator
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  • KALB_6591
  • AHH99950.1
  • acuR1
 7501846 - 7504512 (-) LuxR-family transcription regulator
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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