BGC0000014: ambruticin biosynthetic gene cluster from Sorangium cellulosum
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Location: 1 - 100,708 nt. (total: 100,708 nt).
This entry is originally from NCBI GenBank DQ897667.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000014
Short description ambruticin biosynthetic gene cluster from Sorangium cellulosum
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: DQ897667.1
Compounds
  • ambruticin
Species Sorangium cellulosum [taxonomy]
References
Chemical products information
ambruticin
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C28H42O6
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABK32246.1
1 - 979 (-) histidine kinase response regulator
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  • ABK32247.1
976 - 1950 (-) hypothetical protein
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  • ABK32248.1
2126 - 2797 (-) hypothetical protein
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  • ABK32249.1
  • amb1
2782 - 3732 (-) Amb1
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  • ABK32250.1
  • amb2
5316 - 6536 (+) Amb2
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  • ABK32251.1
  • amb3
6678 - 7457 (+) Amb3
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  • ABK32252.1
  • amb4
7454 - 8839 (+) Amb4
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  • ABK32253.1
  • amb5
9649 - 11175 (-) Amb5
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  • ABK32254.1
  • amb6
11205 - 12638 (+) Amb6
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  • ABK32255.1
  • ambA
14581 - 17772 (+) AmbA
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  • ABK32256.1
  • ambB
17829 - 28898 (+) AmbB
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  • ABK32257.1
  • ambC
28895 - 39862 (+) AmbC
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  • ABK32258.1
  • ambD
39859 - 45537 (+) AmbD
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  • ABK32259.1
  • ambE
45534 - 56057 (+) AmbE
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  • ABK32260.1
  • ambF
56054 - 62647 (+) AmbF
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  • ABK32261.1
  • ambI
62644 - 63963 (+) AmbI
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  • ABK32262.1
  • ambG
64142 - 66361 (+) AmbG
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  • ABK32263.1
  • ambH
66403 - 71724 (+) AmbH
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  • ABK32264.1
  • ambJ
71750 - 73171 (+) AmbJ
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  • ABK32265.1
  • ambP
73690 - 74760 (-) AmbP
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  • ABK32266.1
  • ambO
74763 - 75890 (-) AmbO
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  • ABK32267.1
  • ambN
75965 - 77593 (-) AmbN
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  • ABK32268.1
  • ambQ
77623 - 79227 (+) AmbQ
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  • ABK32269.1
  • ambR
79314 - 80654 (+) AmbR
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  • ABK32270.1
  • ambS
80753 - 81832 (+) AmbS
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  • ABK32271.1
  • ambM
81868 - 83055 (-) AmbM
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  • ABK32272.1
83168 - 83422 (-) hypothetical protein
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  • ABK32273.1
83473 - 83733 (-) hypothetical protein
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  • ABK32274.1
83736 - 84137 (-) hypothetical protein
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  • ABK32275.1
  • amb7
84168 - 90431 (-) Amb7
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  • ABK32276.1
  • amb8
90669 - 91376 (-) Amb8
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  • ABK32277.1
  • amb9
91258 - 92376 (+) Amb9
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  • ABK32278.1
92547 - 95507 (+) hypothetical protein
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  • ABK32279.1
97015 - 99912 (-) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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