BGC0000047: 10,11-dihydro-8-deoxy-12,13-deepoxy-12,13-dihydrochalcomycin biosynthetic gene cluster from Streptomyces sp. KCTC 0041BP
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Location: 1 - 75,439 nt. (total: 75,439 nt).
This entry is originally from NCBI GenBank AY118081.2.

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core biosynthetic genes
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000047
Short description 10,11-dihydro-8-deoxy-12,13-deepoxy-12,13-dihydrochalcomycin biosynthetic gene cluster from Streptomyces sp. KCTC 0041BP
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AY118081.2
Compounds
  • 10,11-dihydro-8-deoxy-12,13-deepoxy-12,13-dihydrochalcomycin
Species Streptomyces sp. KCTC 0041BP [taxonomy]
References
Chemical products information
10,11-dihydro-8-deoxy-12,13-deepoxy-12,13-dihydrochalcomycin
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C34H58O12
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABB52538.1
  • ger1
 580 - 2118 (-) putative transferase protein
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  • ABB52537.1
  • ger2
 2419 - 4473 (-) hypothetical protein
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  • ABB52536.1
  • ger3
 4661 - 5656 (-) hypothetical protein
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  • ABB52535.1
  • ger4
 5808 - 6812 (-) hypothetical protein
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  • ABB52534.1
  • gerO
 6859 - 7863 (-) putative oxidoreductase
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  • ABB52533.1
  • gerB
 7964 - 9181 (-) 3,4-dehydratase-like protein
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  • ABB52532.1
  • gerMI
 9314 - 10129 (-) sugar-O-methyltransferase
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  • ABB52531.1
  • gerN
 10291 - 11748 (-) NDP-4,6-dideoxyhexose-3,4-enoyl reductase
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  • ABB52530.1
  • gerR
 11834 - 14305 (-) beta glucosidase
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  • ABB52529.1
  • gerPI
 14467 - 15672 (-) cytochrome P-450
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  • ABB52528.1
  • gerPII
 15738 - 16961 (-) cytochrome P-450
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  • ABB52527.1
  • gerG
 16976 - 17800 (-) type II thioesterase
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  • ABB52526.1
  • gerE
 17821 - 18783 (-) dTDP-glucose-4,6-dehydratase
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  • ABB52525.1
  • gerD
 18835 - 19722 (-) alpha-D-glucose-1-phosphate thymidylyltransferase
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  • ABB52524.1
  • gerF
 20062 - 20652 (-) NDP-hexose-3-epimerase
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  • ABB52523.1
  • gerMII
 20718 - 21485 (-) 3-O-methyltransferase
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  • ABB52539.1
  • gerPIII
 21746 - 23008 (+) cytochrome P-450
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  • ABB52540.1
  • gerH
 23026 - 23247 (+) ferredoxin
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  • ABB52541.1
  • gerKI
 23244 - 24224 (+) hexose-4-ketoreductase
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  • ABB52542.1
  • gerMIII
 24256 - 25467 (+) O-methyltransferase
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  • ABB52543.1
  • gerTI
 25523 - 26779 (+) 6-deoxy-D-allosyltransferase
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  • ABB52522.1
  • gerA
 26850 - 27692 (-) 23S rRNA-methyltransferase
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  • AAM81584.2
  • gerSI
 27962 - 41125 (+) putative type I polyketide synthase
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  • AAM81585.1
  • gerSII
 41222 - 47152 (+) putative type I polyketide synthase
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  • AAM81586.2
  • gerSIII
 47282 - 58486 (+) putative type I polyketide synthase
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  • ABB52544.1
  • gerSIV
 58537 - 63393 (+) putative type I polyketide synthase
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  • ABB52545.1
  • gerSV
 63500 - 67573 (+) putative type I polyketide synthase
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  • ABB52546.1
  • gerY
 67655 - 68869 (+) NDP-hexose-3,4-isomerase
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  • ABB52547.1
  • gerTII
 68913 - 70190 (+) chalcosyltransferase
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  • ABB52548.1
  • gerKII
 70304 - 71050 (+) 3-oxoacyl-(acyl-carrier-protein)-reductase
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  • ABB52549.1
  • ger31
 73062 - 74804 (+) putative transcriptional regulator
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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