BGC0000082: kijanimicin biosynthetic gene cluster from Actinomadura kijaniata
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Location: 1 - 107,627 nt. (total: 107,627 nt).
This entry is originally from NCBI GenBank EU301739.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000082
Short description kijanimicin biosynthetic gene cluster from Actinomadura kijaniata
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: EU301739.1
Compounds
  • kijanimicin
Species Actinomadura kijaniata [taxonomy]
References
Chemical products information
kijanimicin
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C67H100N2O24
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACB46462.1
 3 - 941 (+) fructokinase
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  • KijA1
  • ACB46463.1
 1026 - 1850 (-) sugar-O-methyltransferase
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  • KijA2
  • ACB46464.1
 1974 - 2954 (-) unknown
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  • KijA3
  • ACB46465.1
 3095 - 4273 (-) p450 monooxygenase
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  • KijA4
  • ACB46466.1
 4339 - 5619 (-) glycosyltransferase
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  • KijA5
  • ACB46467.1
 5920 - 7383 (+) efflux permease
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  • KijA6
  • ACB46468.1
 7444 - 7755 (-) heat shock protein GroES
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  • KijA7
  • ACB46469.1
 7905 - 9533 (-) heat shock protein GroEL
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  • KijA8
  • ACB46470.1
 9904 - 10536 (+) TetR type regulatory protein
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  • KijS4
  • ACB46471.1
 10561 - 22326 (-) polyketide synthase
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  • KijB1
  • ACB46472.1
 22540 - 23979 (+) sugar 2,3-dehydratase
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  • KijB2
  • ACB46473.1
 24021 - 24791 (+) thioesterase
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  • KijB3
  • ACB46474.1
 24903 - 26420 (+) FAD-dependent oxidoreductase
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  • KijC1
  • ACB46475.1
 26565 - 27770 (+) glycosyltransferase
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  • KijC2
  • ACB46476.1
 27782 - 28777 (-) sugar 4-ketoreductase
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  • KijC3
  • ACB46477.1
 28839 - 30092 (-) glycosyltransferase
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  • KijC4
  • ACB46478.1
 30133 - 31326 (-) glycosyltransferase
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  • KijC5
  • ACB46479.1
 31487 - 32086 (+) TetR type regulatory protein
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  • KijE
  • ACB46480.1
 32122 - 33975 (-) hydrolase superfamily dihydrolipoamide acyltransferase-like protein
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  • KijD
  • ACB46481.1
 33972 - 34199 (-) ACP
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  • KijC
  • ACB46482.1
 34196 - 36082 (-) FkbH-like protein
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  • KijB
  • ACB46483.1
 36079 - 37107 (-) ketoacyl acylcarrier protein synthase III
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  • KijA
  • ACB46484.1
 37164 - 38636 (-) FAD-dependent oxidoreductase
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  • KijS5
  • ACB46485.1
 38626 - 43038 (-) polyketide synthase
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  • KijS3
  • ACB46486.1
 43118 - 48496 (-) polyketide synthase
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  • KijS2
  • ACB46487.1
 48520 - 69138 (-) polyketide synthase
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  • KijS1
  • ACB46488.1
 69155 - 87880 (-) polyketide synthase
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  • KijD1
  • ACB46489.1
 88509 - 89753 (-) sugar 3-C-methyl transferase
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  • KijD2
  • ACB46490.1
 89836 - 90957 (-) sugar 3-aminotransferase
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  • KijD3
  • ACB46491.1
 90964 - 92277 (-) FAD-dependent oxidoreductase
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  • KijD4
  • ACB46492.1
 92341 - 93369 (-) sugar 4,6-dehydratase
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  • KijD5
  • ACB46493.1
 93356 - 94252 (-) sugar nucleotidyltransferase
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  • KijD6
  • ACB46494.1
 94372 - 94911 (-) NADPH-dependent flavin reductase
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  • KijD7
  • ACB46495.1
 94935 - 96086 (-) sugar 4-aminotransferase
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  • KijD8
  • ACB46496.1
 96321 - 97103 (+) SAM-dependent methyltransferase
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  • KijD9
  • ACB46497.1
 97138 - 98313 (-) glycosyltransferase
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  • KijD10
  • ACB46498.1
 98397 - 99395 (-) sugar 3-ketoreductase
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  • KijD11
  • ACB46499.1
 99457 - 100065 (-) sugar 5-epimerase
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  • KijD12
  • ACB46500.1
 100109 - 100912 (-) TetR type regulatory protein
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  • ACB46501.1
 102602 - 103531 (-) D-ala, D-ala carboxypeptidase
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  • ACB46502.1
 103802 - 104389 (+) conserved hypothetical protein
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  • ACB46503.1
 104386 - 105006 (-) permease
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  • ACB46504.1
 105003 - 106403 (-) selenium binding protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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