BGC0000118: pactamycin biosynthetic gene cluster from Streptomyces pactum
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Location: 1 - 42,898 nt. (total: 42,898 nt).
This entry is originally from NCBI GenBank AB303063.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000118
Short description pactamycin biosynthetic gene cluster from Streptomyces pactum
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB303063.1
Compounds
  • pactamycin
Species Streptomyces pactum [taxonomy]
References
Chemical products information
pactamycin
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C28H38N4O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAF92582.1
 2 - 1882 (+) ATP-dependent RNA helicase
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  • BAF92583.1
  • pctA
 3807 - 5000 (-) cytochrome P450 monooxygenase
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  • BAF92584.1
  • pctB
 5054 - 5542 (-) glutathione peroxidase
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  • BAF92585.1
  • pctC
 5759 - 6934 (-) aminotransferase
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  • BAF92586.1
  • pctD
 6949 - 8661 (-) carbamoyltransferase
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  • BAF92587.1
  • pctE
 8934 - 10037 (+) Fe-S Radical SAM oxidoreductase
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  • BAF92588.1
  • pctF
 10103 - 11179 (+) methyltransferase
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  • BAF92589.1
  • pctG
 11172 - 11708 (-) hypothetical protein
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  • BAF92590.1
  • pctH
 11708 - 12358 (-) hypothetical protein
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  • BAF92591.1
  • pctI
 12534 - 13670 (-) putative deacetylase
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  • BAF92592.1
  • pctJ
 14089 - 16074 (+) methyltransferase
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  • BAF92593.1
  • pctK
 16106 - 16390 (+) acyl carrier protein
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  • BAF92594.1
  • pctL
 16396 - 17352 (+) glycosyltransferase
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  • BAF92595.1
  • pctM
 17349 - 19037 (+) ketoacyl-ACP synthase
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  • BAF92596.1
  • pctN
 19030 - 20757 (+) methyltransferase
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  • BAF92597.1
  • pctO
 20808 - 22544 (+) methyltransferase
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  • BAF92598.1
  • pctP
 22548 - 23603 (+) putative NAD dependent dehydrogenase
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  • BAF92599.1
  • pctQ
 23914 - 24687 (-) hydrolase
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  • BAF92600.1
  • pctR
 24797 - 25432 (+) phosphopantetheinyl transferase
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  • BAF92601.1
  • pctS
 26388 - 31973 (-) iterative type I PKS
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  • BAF92602.1
  • pctT
 31970 - 33046 (-) ketoacyl-ACP synthase
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  • BAF92603.1
  • pctU
 33060 - 34577 (-) putative AMP-forming acyl-CoA synthetase
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  • BAF92604.1
  • pctV
 34574 - 35908 (-) aminotransferase
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  • BAF92605.1
  • pctW
 36069 - 36908 (+) putative short-chain dehydrogenase/reductase
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  • BAF92606.1
  • pctX
 36946 - 37626 (+) putative phosphatase
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  • BAF92607.1
 38551 - 39366 (+) hypothetical protein
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  • BAF92608.1
 40102 - 41397 (+) integral membrane protein
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  • BAF92609.1
 41963 - >42898 (+) probable peptidase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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