BGC0000164: tetronomycin biosynthetic gene cluster from Streptomyces sp. NRRL 11266
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Location: 1 - 113,234 nt. (total: 113,234 nt).
This entry is originally from NCBI GenBank AB193609.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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General
Compounds
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Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000164
Short description tetronomycin biosynthetic gene cluster from Streptomyces sp. NRRL 11266
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AB193609.1
via
Compounds
  • tetronomycin
Species Streptomyces sp. NRRL 11266 [taxonomy]
References
Chemical products information
tetronomycin Evidence:
Copy SMILES
C34H49Na1O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAE93717.1
  • tmn3
 <1 - 901 (-) putative transcriptional regulator, LuxR family
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    • BAE93718.1
    • tmn4
    		 1056 - 1523 (+) hypothetical protein
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      • BAE93719.1
      • tmn5
      		 2518 - 5250 (+) putative transcriptional regulator, LuxR family
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        • BAE93720.1
        • tmn6
        		 5425 - 6216 (+) putative type II thioesterase
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          • BAF73715.1
          • tmn7a
          		 6245 - 6472 (+) acyl carrier protein
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            • BAE93721.1
            • tmn7
            		 6469 - 7347 (+) putative 2-oxoacid dehydrogenases acyltransferase
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              • BAE93722.1
              • tmnA1
              		 7524 - 22142 (-) type I polyketide synthase
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                • BAE93723.1
                • tmn10
                		 22261 - 22932 (-) putative DedA family membrane-associated protein
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                  • BAF73716.1
                  • tmn8
                  		 23030 - 23602 (-) putative ribosomal protein L15P
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                    • BAE93724.1
                    • tmn9
                    		 23752 - 25254 (-) putative FAD-dependent monooxygenase
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                      • BAE93725.1
                      • tmnVI
                      		 25324 - 30048 (-) type I polyketide synthase
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                        • BAE93726.1
                        • tmnB
                        		 30166 - 30591 (-) probable epoxide hydrolase
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                          • BAE93727.1
                          • tmn12
                          		 30800 - 31702 (+) putative methyltransferase
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                            • BAE93728.1
                            • tmnAII
                            		 31918 - 36894 (+) type I polyketide synthase
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                              • BAE93729.1
                              • tmnAIII
                              		 36935 - 47161 (+) type I polyketide synthase
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                                • BAE93730.1
                                • tmnAIV
                                		 47265 - 64238 (+) type I polyketide synthase
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                                  • BAE93731.1
                                  • tmnAV
                                  		 64292 - 82183 (+) type I polyketide synthase
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                                    • BAE93732.1
                                    • tmnC
                                    		 82294 - 83715 (-) putative tetronomycin epoxidase
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                                      • BAE93733.1
                                      • tmn14a
                                      		 83903 - 84145 (+) putative ferredoxin
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                                        • BAE93734.1
                                        • tmn14
                                        		 84250 - 85452 (+) putative cytochrome P450-like protein
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                                          • BAE93735.1
                                          • tmn15
                                          		 85457 - 86497 (+) putative 3-oxoacyl-(acyl-carrier-protein) synthase III
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                                            • BAE93736.1
                                            • tmn16
                                            		 86793 - 88694 (+) hypothetical protein
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                                              • BAE93737.1
                                              • tmn17
                                              		 88691 - 89728 (+) putative hydrolase or acyltransferase
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                                                • BAE93738.1
                                                • tmn18
                                                		 90184 - 90954 (+) putative pathway specific activator
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                                                  • BAE93739.1
                                                  • tmnDII
                                                  		 91130 - 95656 (-) type I polyketide synthase-related protein
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                                                    • BAE93740.1
                                                    • tmnDI
                                                    		 95688 - 103154 (-) type I polyketide synthase-related protein
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                                                      • BAE93741.1
                                                      • tmn20
                                                      		 103414 - 105168 (+) putative acyltransferase family protein
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                                                        • BAE93742.1
                                                        • tmn21
                                                        		 105209 - 105907 (-) putative TetR-family transcriptional regulator
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                                                          • BAE93743.1
                                                          • tmn22
                                                          		 105907 - 107010 (-) putative membrane protein
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                                                            • BAE93744.1
                                                            • tmn23
                                                            		 107270 - 108862 (+) hypothetical protein
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                                                              • BAE93745.1
                                                              • tmn24
                                                              		 108964 - 110211 (+) hypothetical protein
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                                                                • BAE93746.1
                                                                • tmn25
                                                                		 110322 - 112313 (+) hypothetical protein
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                                                                  • BAE93747.1
                                                                  • tmn26
                                                                  		 112404 - 113111 (+) hypothetical protein
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                                                                    Biosynthesis information

                                                                    No biosynthesis information available for this record.

                                                                    Annotation changelog

                                                                    Entry version: 4

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    2022-10-07
                                                                    Update chemical activity to schema version 2.11
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                    Entry version: 3

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    2022-09-15
                                                                    Updated bioactivity data
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                    Entry version: 2

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    2019-10-16
                                                                    Migrated from v1.4
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                    Entry version: 1

                                                                    Date
                                                                    Changes
                                                                    Submitters
                                                                    Reviewers
                                                                    2015-06-12
                                                                    Submitted
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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