BGC0000178: elansolid A1 biosynthetic gene cluster from Chitinophaga sancti
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Location: 1 - 78,240 nt. (total: 78,240 nt).
This entry is originally from NCBI GenBank HQ680975.1.

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core biosynthetic genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000178
Short description elansolid A1 biosynthetic gene cluster from Chitinophaga sancti
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Trans-AT type I)
Loci
HQ680975.1
via
Compounds
  • elansolid A1
Species Chitinophaga sancti [taxonomy]
References
Chemical products information
elansolid A1 Evidence:
Copy SMILES
C38H52O7
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AEC04346.1
 40 - 1314 (-) major facilitator superfamily protein
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    • AEC04347.1
    • elaA
    		 1734 - 2258 (+) NusG antitermination factor
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      • AEC04348.1
      • elaB
      		 2293 - 4662 (+) PfaD family protein
      • Scaffold biosynthesis
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      • AEC04349.1
      • elaC
      		 4683 - 5684 (+) acyltransferase
      • Scaffold biosynthesis
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      • AEC04350.1
      • elaD
      		 5688 - 5963 (+) hypothetical protein
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        • AEC04351.1
        • elaE
        		 5995 - 6240 (+) acyl carrier protein
        • Tailoring
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        • AEC04352.1
        • elaF
        		 6221 - 7450 (+) beta-ketoacyl acyl carrier protein synthase
        • Scaffold biosynthesis
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        • AEC04353.1
        • elaG
        		 7518 - 8780 (+) cytochrome P450
        • Tailoring
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        • AEC04354.1
        • elaH
        		 8805 - 9416 (+) hypothetical protein
        • Regulation
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        • AEC04355.1
        • elaI
        		 9455 - 10126 (+) putative chorismate lyase
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          • AEC04356.1
          • elaJ
          		 10135 - 18318 (+) polyketide synthase
          • Scaffold biosynthesis
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          • AEC04357.1
          • elaK
          		 18337 - 35742 (+) polyketide synthase
          • Scaffold biosynthesis
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          • AEC04358.1
          • elaL
          		 35776 - 37029 (+) hydroxymethylglutaryl-CoA synthase
          • Tailoring
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          • AEC04359.1
          • elaM
          		 37017 - 37808 (+) enoyl-CoA hydratase/isomerase
          • Tailoring
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          • AEC04360.1
          • elaN
          		 37815 - 38564 (+) enoyl-CoA hydratase/isomerase
          • Tailoring
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          • AEC04361.1
          • elaO
          		 38576 - 43660 (+) polyketide synthase
          • Scaffold biosynthesis
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          • AEC04362.1
          • elaP
          		 43662 - 57434 (+) polyketide synthase
          • Scaffold biosynthesis
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          • AEC04363.1
          • elaQ
          		 57483 - 70769 (+) polyketide synthase
          • Scaffold biosynthesis
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          • AEC04364.1
          • elaR
          		 70776 - 76511 (+) polyketide synthase
          • Scaffold biosynthesis
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          • AEC04365.1
          • elaS
          		 76572 - 77399 (+) methyltransferase
          • Tailoring
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          Biosynthesis information

          Biosynthetic modules

          Name
          0
          Type
          pks-trans-at-starter
          Genes
          elaJ
          Substrates
          Integrated Monomers
          Domains
          ligase, carrier (ACP)
          Name
          1
          Type
          pks-trans-at
          Genes
          elaJ
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, dehydratase, carrier (ACP)
          Name
          2
          Type
          pks-trans-at
          Genes
          elaJ elaK
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, methyltransferase, carrier (ACP)
          Name
          3
          Type
          pks-trans-at
          Genes
          elaK
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, dehydratase, enoylreductase, methyltransferase, carrier (ACP)
          Name
          4
          Type
          pks-trans-at
          Genes
          elaK
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, dehydratase, carrier (ACP)
          Name
          5
          Type
          pks-trans-at
          Genes
          elaK
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, carrier (ACP)
          Name
          6
          Type
          pks-trans-at
          Genes
          elaO
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, carrier (ACP)
          Name
          7
          Type
          pks-trans-at
          Genes
          elaO elaP
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, dehydratase, carrier (ACP)
          Name
          8
          Type
          pks-trans-at
          Genes
          elaP
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, carrier (ACP)
          Name
          9
          Type
          pks-trans-at
          Genes
          elaP
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, dehydratase, carrier (ACP)
          Name
          10
          Type
          pks-trans-at
          Genes
          elaP elaQ
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, dehydratase, methyltransferase, carrier (ACP)
          Name
          11
          Type
          pks-trans-at
          Genes
          elaQ
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, carrier (ACP)
          Name
          12
          Type
          pks-trans-at
          Genes
          elaQ
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, dehydratase, methyltransferase, carrier (ACP)
          Name
          13
          Type
          pks-trans-at
          Genes
          elaQ elaR
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, ketoreductase, dehydratase, carrier (ACP)
          Name
          14
          Type
          pks-trans-at
          Genes
          elaR
          Substrates
          Integrated Monomers
          Domains
          ketosynthase, carrier (ACP)
          Annotation changelog

          Entry version: 4

          Date
          Changes
          Submitters
          Reviewers
          2022-10-07
          Update chemical activity to schema version 2.11
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 3

          Date
          Changes
          Submitters
          Reviewers
          2022-09-15
          Fixed incorrect gene id in annotations
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Remove leading/trailing whitespace in gene identifiers
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Removed ketoreductase stereochemistry annotation from modules without ketoreductases
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Merged cross-CDS PKS modules
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 2

          Date
          Changes
          Submitters
          Reviewers
          2019-10-16
          Migrated from v1.4
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          2015-06-12
          Submitted
          • (ID: 7SR74ARK6JXRBGJRGO2LUHE7)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Detailed domain annotation
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