BGC0000203: BE-7585A biosynthetic gene cluster from Amycolatopsis orientalis subsp. vinearia
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 48,405 nt. (total: 48,405 nt).
This entry is originally from NCBI GenBank HM055942.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000203
Short description BE-7585A biosynthetic gene cluster from Amycolatopsis orientalis subsp. vinearia
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
HM055942.1
via
Compounds
  • BE-7585A
Species Amycolatopsis orientalis subsp. vinearia [taxonomy]
References
Chemical products information
BE-7585A Evidence:
Copy SMILES
C37H46O20S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADI71432.1
 150 - 3464 (+) putative carbamoyl-phosphate synthase large subunit
    copy AA seq
    copy Nt seq
    • ADI71433.1
    		 3461 - 4309 (+) putative orotidine 5'-phosphate decarboxylase subfamily 2
      copy AA seq
      copy Nt seq
      • ADI71434.1
      		 4417 - 4734 (+) putative integration host factor
        copy AA seq
        copy Nt seq
        • ADI71435.1
        		 4731 - 5384 (+) putative guanylate kinase
          copy AA seq
          copy Nt seq
          • ADI71436.1
          		 5381 - 5650 (+) putative DNA-directed RNA polymerase omega subunit
            copy AA seq
            copy Nt seq
            • ADI71437.1
            		 5643 - 6863 (+) putative phosphopantothenoylcysteine synthase/decarboxylase
              copy AA seq
              copy Nt seq
              • ADI71438.1
              		 6957 - 8159 (+) putative methionine adenosyltransferase
                copy AA seq
                copy Nt seq
                • ADI71439.1
                		 8264 - 10360 (+) putative primosomal protein N'
                  copy AA seq
                  copy Nt seq
                  • ADI71440.1
                  • bexR1
                  		 11012 - 11689 (+) putative transcriptional regulator
                    copy AA seq
                    copy Nt seq
                    • ADI71441.1
                    • bexE
                    		 11964 - 13427 (+) putative oxygenase
                      copy AA seq
                      copy Nt seq
                      • ADI71442.1
                      • bexF
                      		 13451 - 13777 (+) putative cyclase
                        copy AA seq
                        copy Nt seq
                        • ADI71443.1
                        • bexA
                        		 13774 - 15042 (+) putative ketosynthase alpha subunit
                          copy AA seq
                          copy Nt seq
                          • ADI71444.1
                          • bexB
                          		 15039 - 16310 (+) putative ketosynthase beta subunit
                            copy AA seq
                            copy Nt seq
                            • ADI71445.1
                            • bexC
                            		 16313 - 16573 (+) putative acyl carrier protein
                              copy AA seq
                              copy Nt seq
                              • ADI71446.1
                              • bexD
                              		 16605 - 17390 (+) putative ketoreductase
                                copy AA seq
                                copy Nt seq
                                • ADI71447.1
                                • bexL
                                		 17418 - 18347 (+) putative cyclase
                                  copy AA seq
                                  copy Nt seq
                                  • ADI71448.1
                                  • bexM
                                  		 18344 - 20302 (+) putative oxygenase-reductase
                                    copy AA seq
                                    copy Nt seq
                                    • ADI71449.1
                                    • bexJ1
                                    		 20308 - 21501 (+) putative transporter
                                      copy AA seq
                                      copy Nt seq
                                      • ADI71450.1
                                      • bexN
                                      		 21498 - 22598 (+) putative carboxyl transferase
                                        copy AA seq
                                        copy Nt seq
                                        • ADI71451.1
                                        • bexH
                                        		 22595 - 23512 (+) putative sugar epimerase/reductase
                                          copy AA seq
                                          copy Nt seq
                                          • ADI71452.1
                                          • bexI
                                          		 23509 - 24156 (+) putative oxygenase
                                            copy AA seq
                                            copy Nt seq
                                            • ADI71453.1
                                            • bexK
                                            		 24158 - 25378 (+) putative hydroxylase
                                              copy AA seq
                                              copy Nt seq
                                              • ADI71454.1
                                              • bexO
                                              		 25375 - 25596 (+) putative ferredoxin
                                                copy AA seq
                                                copy Nt seq
                                                • ADI71455.1
                                                • bexP
                                                		 25593 - 26354 (+) putative methyltransferase
                                                  copy AA seq
                                                  copy Nt seq
                                                  • ADI71456.1
                                                  • bexG1
                                                  		 26351 - 27634 (+) putative glycosyltransferase
                                                    copy AA seq
                                                    copy Nt seq
                                                    • ADI71457.1
                                                    • bexQ
                                                    		 27631 - 28611 (+) putative sugar 3-ketoreductase
                                                      copy AA seq
                                                      copy Nt seq
                                                      • ADI71458.1
                                                      • bexS
                                                      		 28608 - 29591 (+) putative sugar 4,6-dehydratase
                                                        copy AA seq
                                                        copy Nt seq
                                                        • ADI71459.1
                                                        • bexT
                                                        		 29601 - 30914 (+) putative sugar 3-dehydrase
                                                          copy AA seq
                                                          copy Nt seq
                                                          • ADI71460.1
                                                          • bexU
                                                          		 30911 - 31798 (+) putative TDP-glucose synthase
                                                            copy AA seq
                                                            copy Nt seq
                                                            • ADI71461.1
                                                            • bexV
                                                            		 31810 - 33129 (+) putative sugar 2,3-dehydratase
                                                              copy AA seq
                                                              copy Nt seq
                                                              • ADI71462.1
                                                              • bexR2
                                                              		 33133 - 33777 (-) putative transcriptional regulator
                                                                copy AA seq
                                                                copy Nt seq
                                                                • ADI71463.1
                                                                • bexW
                                                                		 33880 - 34491 (+) putative reductase
                                                                  copy AA seq
                                                                  copy Nt seq
                                                                  • ADI71464.1
                                                                  • bexJ2
                                                                  		 34488 - 35936 (+) putative transporter
                                                                    copy AA seq
                                                                    copy Nt seq
                                                                    • ADI71465.1
                                                                    • bexX
                                                                    		 35933 - 36703 (+) putative thiosugar synthase
                                                                      copy AA seq
                                                                      copy Nt seq
                                                                      • ADI71466.1
                                                                      • bexY
                                                                      		 37307 - 38524 (+) putative transporter
                                                                        copy AA seq
                                                                        copy Nt seq
                                                                        • ADI71467.1
                                                                        • bexG2
                                                                        		 38521 - 39909 (+) putative glycosyltransferase
                                                                          copy AA seq
                                                                          copy Nt seq
                                                                          • ADI71468.1
                                                                          		 40071 - 41825 (-) putative secreted protein
                                                                            copy AA seq
                                                                            copy Nt seq
                                                                            • ADI71469.1
                                                                            		 41904 - 42719 (-) putative lysozyme M1 precursor
                                                                              copy AA seq
                                                                              copy Nt seq
                                                                              • ADI71470.1
                                                                              		 42924 - 44723 (+) putative gamma-glutamyltranspeptidase
                                                                                copy AA seq
                                                                                copy Nt seq
                                                                                • ADI71471.1
                                                                                		 44814 - 45740 (+) putative methionyl-tRNA formyltransferase
                                                                                  copy AA seq
                                                                                  copy Nt seq
                                                                                  • ADI71472.1
                                                                                  		 45737 - 47161 (+) putative tRNA/rRNA cytosine-C5-methylase
                                                                                    copy AA seq
                                                                                    copy Nt seq
                                                                                    • ADI71473.1
                                                                                    		 47158 - 47655 (+) putative flavoprotein
                                                                                      copy AA seq
                                                                                      copy Nt seq
                                                                                      Biosynthesis information

                                                                                      No biosynthesis information available for this record.

                                                                                      Annotation changelog

                                                                                      Entry version: 3

                                                                                      Date
                                                                                      Changes
                                                                                      Submitters
                                                                                      Reviewers
                                                                                      2024-07-23
                                                                                      MIBiG v4 annotathon
                                                                                      • (ID: C62OJVVH7XOTOTFZSJT727YU)
                                                                                      • (ID: X3QVFXOIMTNXSB4JQGP4RI6A)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                      Entry version: 2

                                                                                      Date
                                                                                      Changes
                                                                                      Submitters
                                                                                      Reviewers
                                                                                      2019-10-16
                                                                                      Migrated from v1.4
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      2019-10-16
                                                                                      Updated compound(s) information (NPAtlas curation)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                      Entry version: 1

                                                                                      Date
                                                                                      Changes
                                                                                      Submitters
                                                                                      Reviewers
                                                                                      2015-06-12
                                                                                      Submitted
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                      Similar known clusters from MIBiG 4.0
                                                                                      Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                                                      Detailed help and explanations are available here.

                                                                                      Click on reference genes to show details of similarities to genes within the current region.
                                                                                      Double click on a reference drawing to reverse the display of the genes.

                                                                                      Click on an accession to open that entry in the MIBiG database.


                                                                                      Location:

                                                                                      Identifier
                                                                                      Identity
                                                                                      Coverage
                                                                                      Detailed domain annotation
                                                                                      Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                                                      A domain glossary is available here, and an explanation of the visualisation is available here.
                                                                                      Selected features only
                                                                                      Show module domains