BGC0000267: saquayamycin Z biosynthetic gene cluster from Micromonospora sp. Tu 6368
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Location: 1 - 36,648 nt. (total: 36,648 nt).
This entry is originally from NCBI GenBank FJ670504.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
Polyketide
Saccharide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000267
Short description saquayamycin Z biosynthetic gene cluster from Micromonospora sp. Tu 6368
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Angucycline)
  • Saccharide (oligosaccharide)
Loci NCBI GenBank: FJ670504.1
Compounds
  • saquayamycin Z
Species Micromonospora sp. Tu 6368 [taxonomy]
References
Chemical products information
saquayamycin Z
Copy SMILES
C72H102O29
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACP19348.1
 1 - 427 (-) hypothetical protein
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  • ACP19349.1
  • saqI
 1126 - 2274 (+) SaqI
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  • ACP19350.1
  • saqP
 2459 - 3358 (+) SaqP
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  • ACP19351.1
  • saqE
 3624 - 5096 (+) SaqE
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  • ACP19352.1
  • saqF
 5125 - 5454 (+) SaqF
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  • ACP19353.1
  • saqA
 5451 - 6719 (+) SaqA
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  • ACP19354.1
  • saqB
 6716 - 7939 (+) SaqB
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  • ACP19355.1
  • saqC
 7964 - 8236 (+) SaqC
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  • ACP19356.1
  • saqD
 8275 - 9039 (+) SaqD
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  • ACP19357.1
  • saqL
 9085 - 10029 (+) SaqL
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  • ACP19358.1
  • saqM
 10094 - 11569 (+) SaqM
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  • ACP19359.1
  • saqN
 11610 - 12371 (+) SaqN
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  • ACP19360.1
  • saqO
 12476 - 13060 (+) SaqO
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  • ACP19361.1
  • saqGT1
 13105 - 14379 (+) SaqGT1
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  • ACP19362.1
  • saqJ
 14376 - 15785 (+) SaqJ
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  • ACP19363.1
  • saqGT2
 15805 - 17136 (+) SaqGT2
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  • ACP19364.1
  • saqGT3
 17121 - 18335 (+) SaqGT3
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  • ACP19365.1
  • saqGT4
 18335 - 19525 (+) SaqGT4
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  • ACP19366.1
  • saqZ1
 19528 - 20127 (+) SaqZ1
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  • ACP19367.1
  • saqR1
 20114 - 20602 (-) SaqR1
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  • ACP19368.1
  • saqK
 20595 - 21218 (-) SaqK
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  • ACP19369.1
  • saqJ1
 21355 - 22911 (+) SaqJ1
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  • ACP19370.1
  • saqGT5
 23224 - 24375 (+) SaqGT5
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  • ACP19371.1
  • saqG
 24390 - 25451 (+) SaqG
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  • ACP19372.1
  • saqH
 25448 - 26428 (+) SaqH
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  • ACP19373.1
  • saqZ3
 26500 - 27468 (+) SaqZ3
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  • ACP19374.1
  • saqQ
 27470 - 28780 (+) SaqQ
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  • ACP19375.1
  • saqGT6
 28780 - 30030 (+) SaqGT6
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  • ACP19376.1
  • saqR
 30089 - 30844 (+) SaqR
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  • ACP19377.1
  • saqS
 30857 - 32260 (+) SaqS
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  • ACP19378.1
  • saqT
 32269 - 33279 (+) SaqT
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  • ACP19379.1
  • saqW
 33585 - 35081 (+) SaqW
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  • ACP19380.1
 35144 - 35599 (-) hypothetical protein
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  • ACP19381.1
 35144 - 36193 (-) hypothetical protein
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Polyketide-specific information
Subclass Angucycline
Starter unit Acetyl-CoA
Ketide length 9
Cyclic? yes
Polyketide-synthases
Genes Properties Modules
saqL
+
saqA
+
saqF 		Synthase subclass: Type II
Saccharide-specific information
Subclass oligosaccharide
Glycosyltransferases
saqGT5
Specificity: D-olivose
Evidence:
  • Knock-out construct
saqGT2
Specificity: L-rhodinose
Evidence:
  • Knock-out construct
saqGT3
Specificity: D-olivose
Evidence:
  • Knock-out construct
saqGT4
Evidence:
  • Sequence-based prediction
saqGT1
Specificity: L-Rhodinose
Evidence:
  • Knock-out construct
saqGT6
Specificity: 2-deoxy-L-fucose
Evidence:
  • Knock-out construct
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: YECXNWBIVB4ZABFMZK4W53HU, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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