BGC0000279: xantholipin biosynthetic gene cluster from Streptomyces flavogriseus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 52,255 nt. (total: 52,255 nt).
This entry is originally from NCBI GenBank GQ421798.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000279
Short description xantholipin biosynthetic gene cluster from Streptomyces flavogriseus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: GQ421798.1
Compounds
  • xantholipin
Species Streptomyces flavogriseus [taxonomy]
References
Chemical products information
xantholipin
Copy SMILES
C27H18Cl1N1O10
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADE22275.1
  • xanY1
 1 - 1419 (-) putative adenosylhomocysteinase
copy AA seq
copy Nt seq
  • ADE22276.1
  • xanY2
 1397 - 2299 (-) 5,10-methylenetetrahydrofolate reductase
copy AA seq
copy Nt seq
  • ADE22277.1
  • xanY3
 2305 - 5802 (-) methionine synthase
copy AA seq
copy Nt seq
  • ADE22278.1
  • xanY4
 5799 - 6791 (-) carbohydrate kinase
copy AA seq
copy Nt seq
  • ADE22279.1
  • xanY5
 6817 - 8037 (-) S-adenosylmethionine synthetase
copy AA seq
copy Nt seq
  • ADE22280.1
  • xanO1
 8146 - 8583 (-) putative oxygenase
copy AA seq
copy Nt seq
  • ADE22281.1
  • xanS1
 8580 - 9803 (-) putative dehydrogenase
copy AA seq
copy Nt seq
  • ADE22282.1
  • xanJ
 9867 - 10595 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ADE22283.1
  • xanP
 10592 - 12211 (+) putative spore coat protein
copy AA seq
copy Nt seq
  • ADE22284.1
  • xanG
 12379 - 13554 (+) putative inactive gylcosyltransferase
copy AA seq
copy Nt seq
  • ADE22285.1
  • xanA
 13542 - 15386 (+) putative asparagine synthase
copy AA seq
copy Nt seq
  • ADE22286.1
  • xanR1
 15392 - 16075 (+) putative transcriptional regulator
copy AA seq
copy Nt seq
  • ADE22287.1
  • xanO2
 16114 - 17316 (+) putative cytochrome P450 hydroxylase
copy AA seq
copy Nt seq
  • ADE22288.1
  • xanK
 17333 - 17602 (+) putative 3Fe-S ferredoxin
copy AA seq
copy Nt seq
  • ADE22289.1
  • xanU
 17599 - 19728 (+) putative antibiotic transporter
copy AA seq
copy Nt seq
  • ADE22290.1
  • xanO3
 19908 - 21086 (+) FAD-binding monooxygenase
copy AA seq
copy Nt seq
  • ADE22291.1
  • xanL
 21147 - 21707 (-) putative lactoylglutathione lyase
copy AA seq
copy Nt seq
  • ADE22292.1
  • xanH
 22057 - 23472 (+) putative non-heme halogenase
copy AA seq
copy Nt seq
  • ADE22293.1
  • xanQ
 23469 - 25070 (+) putative peptide transporter
copy AA seq
copy Nt seq
  • ADE22294.1
  • xanM1
 25067 - 26086 (+) putative O-methyltransferase
copy AA seq
copy Nt seq
  • ADE22295.1
  • xanZ1
 26651 - 27508 (+) putative F420-dependent reductase
copy AA seq
copy Nt seq
  • ADE22296.1
  • xanN
 27593 - 28888 (-) putative integral membrane ion antiporter
copy AA seq
copy Nt seq
  • ADE22297.1
  • xanW
 28985 - 29473 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ADE22298.1
  • xanR2
 29600 - 30061 (+) putative transcriptional regulator
copy AA seq
copy Nt seq
  • ADE22299.1
  • xanM2
 30083 - 31105 (-) putative O-methyltransferase
copy AA seq
copy Nt seq
  • ADE22300.1
  • xanO4
 31120 - 32742 (-) putative FAD-binding monooxygenase
copy AA seq
copy Nt seq
  • ADE22301.1
  • xanM3
 33084 - 34118 (+) putative methyltransferase
copy AA seq
copy Nt seq
  • ADE22302.1
  • xanO5
 34203 - 35798 (+) putative FAD-binding monooxygenase
copy AA seq
copy Nt seq
  • ADE22303.1
  • xanS2
 35868 - 36554 (+) putative short-chain dehydrogenase/reductase SDR
copy AA seq
copy Nt seq
  • ADE22304.1
  • xanZ2
 36759 - 37667 (-) putative oxidoreductase
copy AA seq
copy Nt seq
  • ADE22305.1
  • xanR3
 37715 - 38722 (+) putative transcriptional regulator
copy AA seq
copy Nt seq
  • ADE22306.1
  • xanB1
 38844 - 40187 (-) biotin carboxylase
copy AA seq
copy Nt seq
  • ADE22307.1
  • xanB2
 40190 - 40714 (-) biotin carboxyl carrier protein
copy AA seq
copy Nt seq
  • ADE22308.1
  • xanB3
 40774 - 42468 (-) carboxyl transferase
copy AA seq
copy Nt seq
  • ADE22309.1
  • xanO6
 42546 - 42857 (-) putative monooxygenase
copy AA seq
copy Nt seq
  • ADE22310.1
  • xanO7
 42847 - 43194 (-) putative monooxygenase
copy AA seq
copy Nt seq
  • ADE22311.1
  • xanZ3
 43194 - 43946 (-) putative 3-oxoacyl-ACP reductase
copy AA seq
copy Nt seq
  • ADE22312.1
  • xanO8
 43970 - 44431 (-) putative monooxygenase
copy AA seq
copy Nt seq
  • ADE22313.1
  • xanC1
 44442 - 44909 (-) putative polyketide cyclase
copy AA seq
copy Nt seq
  • ADE22314.1
  • xanE
 45017 - 46303 (-) putative polyketide beta-ketoacyl synthase beta
copy AA seq
copy Nt seq
  • ADE22315.1
  • xanF
 46306 - 47583 (-) putative polyketide beta-ketoacyl synthase alpha
copy AA seq
copy Nt seq
  • ADE22316.1
  • xanC2
 47580 - 48014 (-) putative polyketide cyclase
copy AA seq
copy Nt seq
  • ADE22317.1
  • xanT
 48198 - 48584 (+) CurD-like protein
copy AA seq
copy Nt seq
  • ADE22318.1
  • xanO9
 48596 - 50014 (+) oxidase-like protein
copy AA seq
copy Nt seq
  • ADE22319.1
  • xanO10
 50067 - 50513 (-) putative monooxygenase
copy AA seq
copy Nt seq
  • ADE22320.1
  • xanV
 50528 - 50908 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ADE22321.1
  • xanZ4
 50908 - 51663 (-) 3-oxoacyl-ACP reductase
copy AA seq
copy Nt seq
  • ADE22322.1
  • xanD
 51660 - 51920 (-) acyl carrier protein
copy AA seq
copy Nt seq
  • ADE22323.1
  • xanC3
 51917 - 52255 (-) putative polyketide cyclase
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.