BGC0000302: anabaenopeptin biosynthetic gene cluster from Anabaena sp. 90
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 36,200 nt. (total: 36,200 nt).
This entry is originally from NCBI GenBank GU174493.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000302
Short description anabaenopeptin biosynthetic gene cluster from Anabaena sp. 90
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: GU174493.1
Compounds
  • anabaenopeptin
Species Anabaena sp. 90 [taxonomy]
References
Chemical products information
anabaenopeptin
Copy SMILES
C42H62N10O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACZ55945.1
  • aptA1
 745 - 7332 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • ACZ55942.1
  • aptA2
 7422 - 13946 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • ACZ55943.1
  • aptB
 14004 - 17213 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • ACZ55944.1
  • aptC
 17408 - 25105 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • ACZ55946.1
  • aptD
 25102 - 29313 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • ACZ55947.1
  • aptE
 29356 - 30534 (+) hydroxymethylglutaryl-CoA lyase-like protein
copy AA seq
copy Nt seq
  • ACZ55948.1
  • aptF
 30943 - 33240 (+) ABC transporter
copy AA seq
copy Nt seq
NRP-specific information
Subclass N/A
Cyclic? yes
Release type
  • Hydrolysis
NRP-synthases
Gene Modules
aptA1
Module A0
Specificity: arginine / lysine
Evidence for specificity:
  • Structure-based inference
Module A1
Specificity: lysine
Evidence for specificity:
  • ATP-PPi exchange assay
Condensation domain type: LCL
aptA2
Module B0
Specificity: tyrosine
Evidence for specificity:
  • ATP-PPi exchange assay
Module B1
Specificity: lysine
Evidence for specificity:
  • ATP-PPi exchange assay
Condensation domain type: LCL
aptB
Module 2
Specificity: valine
Evidence for specificity:
  • ATP-PPi exchange assay
Condensation domain type: DCL
aptC
Module 3
Specificity: homotyrosine / alanine / isoleucine / valine / leucine / tyrosine
Evidence for specificity:
  • ATP-PPi exchange assay
Condensation domain type: LCL
Module 4
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: LCL
Modification domains: Methylation
aptD
Module 5
Specificity: phenylalanine
Evidence for specificity:
  • ATP-PPi exchange assay
Condensation domain type: LCL
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: BAJIZJS2YANDM4M7JHS5DFUK, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.