BGC0000362: glycopeptidolipid biosynthetic gene cluster from Mycobacterium avium
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Location: 1 - 71,286 nt. (total: 71,286 nt).
This entry is originally from NCBI GenBank AF143772.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000362
Short description glycopeptidolipid biosynthetic gene cluster from Mycobacterium avium
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
AF143772.2
via
Compounds
  • glycopeptidolipid
Species Mycobacterium avium [taxonomy]
References
Chemical products information
glycopeptidolipid Evidence:
Copy SMILES
C81H142N4O27
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAD44199.1
 47 - 1132 (+) unknown
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    • AAD44200.1
    		 1524 - 2441 (-) IS1601-D
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      • AAD44201.1
      		 2441 - 2785 (-) IS1601-C
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        • AAD44202.1
        		 2837 - 4039 (-) IS1601-B
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          • AAD44203.1
          		 4298 - 5545 (-) IS1601-A
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            • AAD44204.1
            		 5791 - 6876 (+) A-protein-like protein
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              • AAD44205.1
              • gepiA
              		 6996 - 8057 (+) GepiA
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                • AAD44206.1
                • mtfA
                		 8321 - 9448 (+) MtfA
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                  • AAD44207.1
                  • mtfB
                  		 9715 - 10536 (+) MtfB
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                    • AAD44208.1
                    • gtfA
                    		 10658 - 11935 (+) GtfA
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                      • AAD44209.1
                      • rtfA
                      		 12339 - 13625 (+) RtfA
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                        • AAD44210.1
                        • mtfC
                        		 13727 - 14527 (+) MtfC
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                          • AAD44211.1
                          • mtfD
                          		 14627 - 15445 (+) mtfD
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                            • AAD44212.1
                            		 16004 - 17236 (-) transposase
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                              • AAD44213.2
                              • gtfB
                              		 17728 - 18984 (-) GtfB
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                                • AAD44214.2
                                		 19126 - 19779 (+) unknown
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                                  • AAD44215.1
                                  		 20437 - 20781 (+) transposase
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                                    • AAD44216.1
                                    		 20781 - 21698 (+) transposase
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                                      • AAD44217.2
                                      • gdhgA
                                      		 22689 - 23729 (-) GdhgA
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                                        • AAD44218.1
                                        • gtfC
                                        		 24002 - 24811 (+) GtfC
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                                          • AAD44219.1
                                          • mdhtA
                                          		 25020 - 26051 (+) mdhtA
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                                            • AAD44220.1
                                            • merA
                                            		 25991 - 27010 (+) MerA
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                                              • AAD44221.1
                                              		 27286 - 28008 (+) unknown
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                                                • AAD44222.1
                                                • gtfD
                                                		 28153 - 28953 (+) GtfD
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                                                  • AAD44223.1
                                                  		 29601 - 30518 (-) IS1601-D
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                                                    • AAD44224.1
                                                    		 30518 - 30862 (-) IS1601-C
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                                                      • AAD44225.1
                                                      		 30914 - 32116 (-) IS1601-B
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                                                        • AAD44226.1
                                                        		 32375 - 33622 (-) IS1601-A
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                                                          • AAD44227.1
                                                          • drrC
                                                          		 33901 - 34692 (-) DrrC
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                                                            • AAD44228.1
                                                            • drrB
                                                            		 34692 - 35432 (-) DrrB
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                                                              • AAD44229.1
                                                              • drrA
                                                              		 35429 - 36376 (-) DrrA
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                                                                • AAD44230.1
                                                                • tmtpC
                                                                		 36589 - 39513 (-) TmtpC
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                                                                  • AAD44231.1
                                                                  • tmtpB
                                                                  		 39572 - 42463 (-) TmtpB
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                                                                    • AAD44232.1
                                                                    • tmtpA
                                                                    		 42460 - 43125 (-) TmtpA
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                                                                      • AAD44233.1
                                                                      • pstA
                                                                      		 44047 - 54294 (+) PstA
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                                                                        • AAD44234.1
                                                                        • pstB
                                                                        		 54291 - 61949 (+) PstB
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                                                                          • AAD44235.1
                                                                          		 65266 - 66183 (-) IS1601-D
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                                                                            • AAD44236.1
                                                                            		 66183 - 66527 (-) IS1601-C
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                                                                              • AAF63833.1
                                                                              • pstD
                                                                              		 67088 - >71286 (+) PstD
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                                                                                Biosynthesis information

                                                                                Biosynthetic modules

                                                                                Name
                                                                                Unk01
                                                                                Type
                                                                                nrps-type1
                                                                                Genes
                                                                                pstA
                                                                                Substrates
                                                                                phenylalanine (evidence: Structure-based inference [1])
                                                                                Integrated Monomers
                                                                                Domains
                                                                                adenylation
                                                                                Name
                                                                                Unk02
                                                                                Type
                                                                                nrps-type1
                                                                                Genes
                                                                                pstA
                                                                                Substrates
                                                                                threonine (evidence: Structure-based inference [1])
                                                                                Integrated Monomers
                                                                                Domains
                                                                                adenylation
                                                                                Name
                                                                                Unk03
                                                                                Type
                                                                                nrps-type1
                                                                                Genes
                                                                                pstB
                                                                                Substrates
                                                                                alanine (evidence: Structure-based inference [1])
                                                                                Integrated Monomers
                                                                                Domains
                                                                                adenylation
                                                                                Name
                                                                                Unk04
                                                                                Type
                                                                                nrps-type1
                                                                                Genes
                                                                                pstB
                                                                                Substrates
                                                                                alaninol (evidence: Structure-based inference [1])
                                                                                Integrated Monomers
                                                                                Domains
                                                                                adenylation
                                                                                Annotation changelog

                                                                                Entry version: 4

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2022-10-07
                                                                                Update chemical activity to schema version 2.11
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 3

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2022-09-15
                                                                                Updated bioactivity data
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                2022-09-15
                                                                                Added NRP substrate specificities
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 2

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2019-10-16
                                                                                Migrated from v1.4
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 1

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2015-06-12
                                                                                Submitted
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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