BGC0000403

BGC0000403: pelgipeptin biosynthetic gene cluster from Paenibacillus elgii

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Location: 1 - 40,806 nt. (total: 40,806 nt).
This entry is originally from NCBI GenBank JQ745271.1.

core biosynthetic genes

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transport-related genes

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Gene details

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General

Compounds

Genes

NRP

History

NRPS/PKS domains

KnownClusterBlast

General information about the BGC

MIBiG accession	BGC0000403
Short description	pelgipeptin biosynthetic gene cluster from Paenibacillus elgii
Status	Minimal annotation: no A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s) Completeness: Unknown Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)	NRP
Loci	NCBI GenBank: JQ745271.1
Compounds	pelgipeptin
Species	Paenibacillus elgii [taxonomy]
References	Identification and functional analysis of gene cluster involvement in biosynthesis of the cyclic lipopeptide antibiotic pelgipeptin produced by Paenibacillus elgii. Qian CD et al., BMC Microbiol (2012) PMID:22958453

Chemical products information

pelgipeptin

(no structure information available)

List of genes involved in compound(s) production

Identifiers	Position	Product	Extra
AFJ14790.1 plpA	1 - 1287 (+)	PlpA	copy AA seq copy Nt seq
AFJ14791.1 plpB	1362 - 2924 (+)	PlpB	copy AA seq copy Nt seq
AFJ14792.1 plpC	2934 - 3668 (+)	PlpC	copy AA seq copy Nt seq
AFJ14793.1 plpD	3838 - 8364 (+)	PlpD	copy AA seq copy Nt seq
AFJ14794.1 plpE	8405 - 33826 (+)	PlpE	copy AA seq copy Nt seq
AFJ14795.1 plpF	33932 - 37249 (+)	PlpF	copy AA seq copy Nt seq
AFJ14796.1 plpG	37292 - 39076 (+)	PlpG	copy AA seq copy Nt seq
AFJ14797.1 plpH	39073 - 40806 (+)	PlpH	copy AA seq copy Nt seq

NRP-specific information

Subclass	N/A
Cyclic?	no

NRP-synthases

Gene	Modules
plpD	Module ? Specificity: 2,4-diaminobutyric acid Evidence for specificity: Sequence-based prediction Structure-based inference Enzyme-coupled assay
plpE	Module ? Specificity: isoleucine Evidence for specificity: Sequence-based prediction Structure-based inference Enzyme-coupled assay
	Module ? Specificity: 2,4-diaminobutyric acid Evidence for specificity: Sequence-based prediction Structure-based inference
	Module ? Specificity: phenylalanine Evidence for specificity: Sequence-based prediction Structure-based inference Enzyme-coupled assay
	Module ? Specificity: leucine Evidence for specificity: Sequence-based prediction Structure-based inference
	Module ? Specificity: 2,4-diaminobutyric acid Evidence for specificity: Sequence-based prediction Structure-based inference
	Module ? Specificity: valine Evidence for specificity: Sequence-based prediction Structure-based inference
	Module ? Specificity: leucine Evidence for specificity: Sequence-based prediction Structure-based inference
plpF	Module ? Specificity: serine Evidence for specificity: Sequence-based prediction Structure-based inference Enzyme-coupled assay

Annotation changelog

MIBiG version	Submitter	Notes
1.0	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Submitted
2.0	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Migrated from v1.4
3.0	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Updated bioactivity data Added NRP substrate specificities
3.1	Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).	Update chemical activity to schema version 2.11

Detailed domain annotation

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