BGC0000469: bottromycin A2 biosynthetic gene cluster from Streptomyces sp. BC16019
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 39,920 nt. (total: 39,920 nt).
This entry is originally from NCBI GenBank JX235926.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000469
Short description bottromycin A2 biosynthetic gene cluster from Streptomyces sp. BC16019
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Bottromycin)
Loci NCBI GenBank: JX235926.1
Compounds
  • bottromycin A2
Species Streptomyces sp. BC16019 [taxonomy]
References
Chemical products information
bottromycin A2
Copy SMILES
C42H62N8O7S1
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFV25464.1
 14 - 1204 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25465.1
 1309 - 2976 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25466.1
 3064 - 3918 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25467.1
 4067 - 4969 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25468.1
 5074 - 5955 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25469.1
 5948 - 6682 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25470.1
 8518 - 10941 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25471.1
 11018 - 11359 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25472.1
 11793 - 12338 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25473.1
 12477 - 12749 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25474.1
 12847 - 13653 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25475.1
 13747 - 14349 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25476.1
 14941 - 15678 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25477.1
 15757 - 15990 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25478.1
  • botT
 16255 - 17550 (-) BotT
copy AA seq
copy Nt seq
  • AFV25479.1
  • botOMT
 18069 - 18908 (-) BotOMT
copy AA seq
copy Nt seq
  • AFV25480.1
  • botRMT1
 19314 - 21239 (+) BotRMT1
copy AA seq
copy Nt seq
  • AFV25481.1
  • botA
 21336 - 21470 (+) BotA
copy AA seq
copy Nt seq
  • AFV25482.1
  • botC
 21534 - 22838 (+) BotC
copy AA seq
copy Nt seq
  • AFV25483.1
  • botCD
 22951 - 24153 (+) BotCD
copy AA seq
copy Nt seq
  • AFV25484.1
  • botRMT2
 24150 - 26132 (+) BotRMT2
copy AA seq
copy Nt seq
  • AFV25485.1
  • botH
 26119 - 27000 (+) BotH
copy AA seq
copy Nt seq
  • AFV25486.1
  • botAH
 27018 - 28415 (+) BotAH
copy AA seq
copy Nt seq
  • AFV25487.2
  • botCYP
 28405 - 29631 (+) BotCYP
copy AA seq
copy Nt seq
  • AFV25488.1
  • botRMT3
 29639 - 31684 (+) BotRMT3
copy AA seq
copy Nt seq
  • AFV25489.1
  • botR
 31849 - 32403 (+) BotR
copy AA seq
copy Nt seq
  • AFV25490.1
  • botP
 32408 - 33922 (+) BotP
copy AA seq
copy Nt seq
  • AFV25491.1
 34053 - 35306 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25492.1
 35391 - 36143 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25493.1
 36454 - 36978 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25494.1
 37209 - 38132 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25495.1
 38207 - 38485 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AFV25496.1
 38795 - 39901 (-) hypothetical protein
copy AA seq
copy Nt seq
RiPP-specific information
Subclass Bottromycin
Cyclic? no
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.