BGC0000613: thiomuracin A biosynthetic gene cluster from Nonomuraea sp. Bp3714-39
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Location: 1 - 15,586 nt. (total: 15,586 nt).
This entry is originally from NCBI GenBank FJ461360.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000613
Short description thiomuracin A biosynthetic gene cluster from Nonomuraea sp. Bp3714-39
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Thiopeptide)
Loci NCBI GenBank: FJ461360.1
Compounds
  • thiomuracin A
Species Nonomuraea sp. Bp3714-39 [taxonomy]
References
Chemical products information
thiomuracin A
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C59H50N14O12S6
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACS83777.1
  • tpdI
 1 - 1212 (-) coproporphyrinogen III oxidase
  • Scaffold biosynthesis
Sequence-based prediction
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  • ACS83778.1
  • tpdJ1
 1209 - 2372 (-) cytochrome P450 monooxygenase
  • Scaffold biosynthesis
Sequence-based prediction
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  • ACS83779.1
  • tpdJ2
 2369 - 3589 (-) cytochrome P450 monooxygenase
  • Unknown
Sequence-based prediction
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  • ACS83780.1
  • tpdR
 3600 - 4331 (-) TetR transcriptional regulator
  • Regulation
Sequence-based prediction
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  • ACS83781.1
  • tpdA
 4677 - 4826 (+) thiomuracin prepropeptide
  • Scaffold biosynthesis
Sequence-based prediction
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  • ACS83782.1
  • tpdB
 4866 - 7478 (+) dehydratase
  • Scaffold biosynthesis
Sequence-based prediction
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  • ACS83783.1
  • tpdC
 7475 - 8290 (+) dehydratase
  • Scaffold biosynthesis
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  • ACS83784.1
  • tpdD
 8287 - 9246 (+) hypothetical protein
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  • ACS83785.1
  • tpdE
 9243 - 10529 (+) dehydrogenase
  • Scaffold biosynthesis
Sequence-based prediction
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  • ACS83786.1
  • tpdF
 10526 - 12418 (+) hypothetical protein
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  • ACS83787.1
  • tpdG
 12411 - 14255 (+) cyclodehydratase
  • Scaffold biosynthesis
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  • ACS83788.1
  • tpdH
 14252 - 15586 (+) peptidase
  • Scaffold biosynthesis
Sequence-based prediction
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RiPP-specific information
Subclass Thiopeptide
Cyclic? yes
Peptidases
    tpdH
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: O4PIO7VEX2IICIP2RGFFKN3C, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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