BGC0000654: phenalinolactone A biosynthetic gene cluster from Streptomyces sp. Tu6071
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Location: 1 - 49,461 nt. (total: 49,461 nt).
This entry is originally from NCBI GenBank DQ230532.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Saccharide
Terpene
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000654
Short description phenalinolactone A biosynthetic gene cluster from Streptomyces sp. Tu6071
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Terpene (Diterpene/Unknown)
  • Saccharide (hybrid/tailoring)
Loci NCBI GenBank: DQ230532.1
Compounds
  • phenalinolactone A
Species Streptomyces sp. Tu6071 [taxonomy]
References
Chemical products information
phenalinolactone A
Copy SMILES
C38H53N1O12
Chemical database entries
NPAtlas
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABB69733.1
  • plaR1
 6556 - 7353 (-) PlaR1
  • Regulation
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  • ABB69734.1
  • plaR2
 7806 - 8408 (-) PlaR2
  • Regulation
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  • ABB69735.1
  • plaA1
 9161 - 10465 (+) PlaA1
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  • ABB69736.1
  • plaA2
 10462 - 11853 (+) PlaA2
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  • ABB69737.1
  • plaA3
 11866 - 12837 (-) PlaA3
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  • ABB69738.1
  • plaA4
 12837 - 13742 (-) PlaA4
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  • ABB69739.1
  • plaM1
 13739 - 14650 (-) PlaM1
  • Tailoring (Methylation)
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  • ABB69740.1
  • plaP6
 14589 - 15554 (-) PlaP6
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  • ABB69741.1
  • plaO1
 15554 - 16420 (-) PlaO1
  • Tailoring (Unknown)
Activity assay
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  • ABB69742.1
  • plaT1
 16422 - 17771 (-) PlaT1
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  • ABB69743.1
  • plaT2
 17768 - 19483 (-) PlaT2
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  • ABB69744.1
  • plaT3
 19499 - 20512 (-) PlaT3
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  • ABB69745.1
  • plaH
 20514 - 21398 (-) PlaH
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  • ABB69746.1
  • plaO2
 21436 - 22629 (-) PlaO2
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  • ABB69747.1
  • plaM2
 22884 - 23729 (+) PlaM2
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  • ABB69748.1
  • PlaO3
 23753 - 24958 (+) PlaO3
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  • ABB69749.1
  • plaP1
 25098 - 25388 (+) PlaP1
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  • ABB69750.1
  • plaP2
 25401 - 26468 (+) PlaP2
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  • ABB69751.1
  • plaP3
 26458 - 27591 (+) PlaP3
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  • ABB69752.1
  • plaP4
 27588 - 29372 (+) PlaP4
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  • ABB69753.1
  • plaP5
 29386 - 31092 (+) PlaP5
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  • ABB69754.1
  • plaT4
 31153 - 32232 (+) PlaT4
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  • ABB69755.1
  • plaT5
 32273 - 33433 (+) PlaT5
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  • ABB69756.1
  • plaT6
 33430 - 35211 (+) PlaT6
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  • ABB69757.1
  • plaU
 35268 - 36002 (+) PlaU
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  • ABB69758.1
  • plaV
 36051 - 37505 (-) 3-O-acetyl transferase
  • Tailoring (Acetylation)
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  • ABB69759.1
  • plaO4
 37551 - 38726 (-) PlaO4
  • Tailoring (Oxidation)
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  • ABB69760.1
  • plaA5
 38851 - 39858 (+) PlaA5
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  • ABB69761.1
  • plaA6
 41235 - 42425 (+) PlaA6
  • Tailoring (Glycosylation)
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  • ABB69762.1
  • plaA7
 42464 - 43399 (-) PlaA7
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  • ABB69763.1
  • plaA8
 43419 - 43994 (-) PlaA8
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  • ABB69764.1
  • plaO5
 44294 - 45523 (+) PlaO5
  • Tailoring (Hydroxylation)
Activity assay
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  • ABB69765.1
  • plaM3
 45600 - 46412 (+) PlaM3
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  • ABB69766.1
  • plaR3
 47334 - 47693 (-) PlaR3
  • Regulation
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  • ABB69767.1
  • plaZ
 47763 - 48476 (+) PlaZ
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Saccharide-specific information
Subclass hybrid/tailoring
Sugar-encoding genes
  • plaA1, plaA2, plaA3, plaA4, plaA5, plaA7, plaA8
Glycosyltransferases
plaA6
Specificity: L-amicetose
Evidence:
  • Knock-out construct
Terpene-specific information
Carbon count subclass Diterpene
Structural subclass Unknown
Isoprenoid precursor IPP
Prenyltransferases plaT3
Terpene synthases/cyclases plaT1, plaT2, plaT4, plaT5, plaT6
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: LPHAMZXQ3BT6INJWOLKUYGWU, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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