BGC0000667: PR-toxin biosynthetic gene cluster from Penicillium roqueforti FM164
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 3,334,897 - 3,356,025 nt. (total: 21,129 nt).
This entry is originally from NCBI GenBank HG792016.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
Tailoring
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000667
Short description PR-toxin biosynthetic gene cluster from Penicillium roqueforti FM164
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • terpene (Unknown)
Loci
HG792016.1
3342234 - 3350182
via
Compounds
  • PR-toxin
Species Penicillium roqueforti FM164 [taxonomy]
References
Chemical products information
PR-toxin Evidence: NMR [1], Mass spectrometry [1], Chemical derivatisation [1]
Copy SMILES
C17H20O6
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • PROQFM164_S02g001464
  • CDM31314.1
3342799 - 3343870 (-) Short-chain dehydrogenase/reductase SDR
    copy AA seq
    copy Nt seq
    • PROQFM164_S02g001465
    • CDM31315.1
    • ARI1
    3344897 - 3346025 (-) Aristolochene synthase
      copy AA seq
      copy Nt seq
      • PROQFM164_S02g001466
      • CDM31316.1
      3346948 - 3348663 (+) FAD-binding, type 2
        copy AA seq
        copy Nt seq
        • PROQFM164_S02g001467
        • CDM31317.1
        3349183 - 3350172 (-) Short-chain dehydrogenase/reductase SDR
          copy AA seq
          copy Nt seq
          Biosynthesis information

          No biosynthesis information available for this record.

          Annotation changelog

          Entry version: 3

          Date
          Changes
          Submitters
          Reviewers
          MIBiG v4 annotathon
          • (ID: 7DA2QLBWQP4AXXNZI5PHTAAU)
          • (ID: D44UGPXERIZAXNCG2VXZP5I3)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 2

          Date
          Changes
          Submitters
          Reviewers
          Migrated from v1.4
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Updated compound(s) information (NPAtlas curation)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          Submitted
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Tailoring functions
          Tailoring enzymes detected in this region
          Oxidoreductases: dehydrogenase oxidase
          PROQFM164_S02g001464: short-chain dehydrogenase/reductase SDR
          smcogs
          SMCOG1001: short-chain dehydrogenase/reductase SDR
          PROQFM164_S02g001466: FAD linked oxidase domain protein
          smcogs
          SMCOG1138: FAD linked oxidase domain protein
          PROQFM164_S02g001467: short-chain dehydrogenase/reductase SDR
          smcogs
          SMCOG1001: short-chain dehydrogenase/reductase SDR
          Lyases: cyclase
          PROQFM164_S02g001465: Terpene synthase/cyclase metal-binding domain protein
          smcogs
          SMCOG1052: Terpene synthase/cyclase metal-binding domain protein
          Similar known clusters from MIBiG 4.0
          Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
          Detailed help and explanations are available here.

          Click on reference genes to show details of similarities to genes within the current region.
          Double click on a reference drawing to reverse the display of the genes.

          Click on an accession to open that entry in the MIBiG database.


          Location:

          Identifier
          Identity
          Coverage