BGC0000678: pentalenolactone biosynthetic gene cluster from Streptomyces avermitilis MA-4680 = NBRC 14893
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Location: 3,745,497 - 3,758,933 nt. (total: 13,437 nt).
This entry is originally from NCBI GenBank BA000030.3.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000678
Short description pentalenolactone biosynthetic gene cluster from Streptomyces avermitilis MA-4680 = NBRC 14893
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Terpene
Loci NCBI GenBank: BA000030.3
Compounds
  • pentalenolactone
Species Streptomyces avermitilis MA-4680 = NBRC 14893 [taxonomy]
References
Chemical products information
pentalenolactone
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C15H16O5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SAV_2990
  • BAC70701.1
  • gap1
 3745497 - 3746501 (+) glyceraldehyde-3-phosphate dehydrogenase
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  • SAV_2991
  • BAC70702.2
  • ptlH
 3746862 - 3747719 (+) 1-deoxypentalenic acid 11-beta hydroxylase; Fe(II)/alpha-ketoglutarate dependent hydroxylase
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  • SAV_2992
  • BAC70703.1
  • ptlG
 3747777 - 3749231 (+) putative transmembrane efflux protein
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  • SAV_2993
  • BAC70704.1
  • ptlF
 3749307 - 3750119 (+) 1-deoxy-11beta-hydroxypentalenic acid dehydrogenase
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  • SAV_2994
  • BAC70705.1
  • ptlE
 3750177 - 3751961 (+) putative monooxygenase
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  • SAV_2995
  • BAC70706.1
  • ptlD
 3751962 - 3752882 (+) putative dioxygenase
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  • SAV_2996
  • BAC70707.1
  • ptlC
 3752934 - 3753110 (+) hypothetical protein
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  • SAV_2997
  • BAC70708.1
  • ptlB
 3753107 - 3754120 (+) polyprenyl diphosphate synthase
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  • SAV_2998
  • BAC70709.1
  • ptlA
 3754725 - 3755735 (+) pentalenene synthase
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  • SAV_2999
  • BAC70710.1
  • ptlI
 3755792 - 3757141 (+) pentalenene C13 hydroxylase; cytochrome P450
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  • SAV_3000
  • BAC70711.1
  • ptlR
 3757201 - 3757662 (+) putative AraC-family transcriptional regulator
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  • SAV_3001
  • BAC70712.1
  • ptlJ
 3757659 - 3758093 (+) putative lyase
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  • SAV_3002
  • BAC70713.1
  • ptlL
 3758163 - 3758933 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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