BGC0000990: epothilone biosynthetic gene cluster from Sorangium cellulosum
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Location: 1 - 72,852 nt. (total: 72,852 nt).
This entry is originally from NCBI GenBank GU063811.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000990
Short description epothilone biosynthetic gene cluster from Sorangium cellulosum
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: GU063811.1
Compounds
  • epothilone
Species Sorangium cellulosum [taxonomy]
References
Chemical products information
epothilone
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C27H41N1O6S1
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADB12488.1
  • epoA
 437 - 4702 (+) EpoA
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  • ADB12489.1
  • epoB
 4699 - 8931 (+) EpoB
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  • ADB12490.1
  • epoC
 9078 - 14576 (+) EpoC
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  • ADB12491.1
  • epoD
 14573 - 36346 (+) EpoD
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  • ADB12492.1
  • epoE
 36351 - 47747 (+) EpoE
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  • ADB12493.1
  • epoF
 47762 - 55081 (+) EpoF
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  • ADB12494.1
  • epoK
 55196 - 56455 (+) EpoK
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  • ADB12495.1
 56633 - 57172 (+) hypothetical protein
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  • ADB12496.1
 57202 - 57759 (+) hypothetical protein
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  • ADB12497.1
 57847 - 58701 (-) hypothetical protein
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  • ADB12498.1
 58713 - 59180 (-) hypothetical protein
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  • ADB12499.1
 59531 - 59980 (+) hypothetical protein
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  • ADB12500.1
 60188 - 61105 (+) cation efflux protein
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  • ADB12501.1
 61505 - 61903 (+) type I restriction-modification system endonuclease
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  • ADB12502.1
 62141 - 62791 (+) hypothetical protein
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  • ADB12503.1
 62812 - 65931 (+) putative iron-sulfur binding oxidoreductase
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  • ADB12504.1
 65935 - 67296 (+) NrfD family oxidoreductase
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  • ADB12505.1
 67296 - 67832 (+) hypothetical protein
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  • ADB12506.1
 67829 - 68455 (+) hypothetical protein
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  • ADB12507.1
 68452 - 69633 (+) hypothetical protein
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  • ADB12508.1
 69633 - 70001 (+) hypothetical protein
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  • ADB12509.1
 69998 - 70951 (+) hypothetical protein
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  • ADB12510.1
  • COII
 70948 - 72111 (+) cytochrome c oxidase subunit II
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  • ADB12511.1
  • COI
 72108 - >72852 (+) cytochrome c oxidase subunit I
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated reference publication(s) (MIBiG Annotathon)
Detailed domain annotation
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