BGC0001001: jamaicamide A biosynthetic gene cluster from Lyngbya majuscula
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Location: 1 - 69,900 nt. (total: 69,900 nt).
This entry is originally from NCBI GenBank AY522504.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001001
Short description jamaicamide A biosynthetic gene cluster from Lyngbya majuscula
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
AY522504.1
via
Compounds
  • jamaicamide A
  • jamaicamide B
  • jamaicamide C
Species Lyngbya majuscula [taxonomy]
References
Chemical products information
jamaicamide A Evidence: NMR [1]
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C27H36Br1Cl1N2O4
Chemical database entries
NPAtlas
CyanoMetDB CyanoMetDB_1360
jamaicamide B Evidence: NMR [1]
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C27H37Cl1N2O4
Chemical database entries
CyanoMetDB CyanoMetDB_1358
PubCHEM
NPAtlas
jamaicamide C Evidence: NMR [1]
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C27H39Cl1N2O4
Chemical database entries
CyanoMetDB CyanoMetDB_1352
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAS98794.1
 <1 - 2415 (+) sucrose synthase
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    • AAS98795.1
    		 2460 - 2813 (-) hypothetical protein
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      • AAS98796.1
      		 3126 - 3749 (-) putative transposase
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        • AAS98797.1
        		 4382 - 4957 (-) transposase
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          • AAS98774.1
          		 6630 - 8408 (+) hexanoyl-ACP synthetase
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            • AAS98775.1
            		 8591 - 9556 (+) fatty acid desaturase
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              • AAS98798.1
              		 9718 - 10020 (+) ACP
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                • AAS98776.1
                		 10463 - 12514 (+) flavin-dependent halogenase
                • Halogenation
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                • AAS98777.1
                		 12596 - 17788 (+) PKS
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                  • AAS98799.1
                  		 17811 - 18050 (+) ACP
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                    • AAS98778.1
                    		 18222 - 19448 (+) ketosynthase/decarboxylase
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                      • AAS98779.1
                      		 19453 - 20712 (+) HMGCS-like
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                        • AAS98780.1
                        		 20982 - 21746 (+) enoyl hydratase/isomerase
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                          • AAS98781.1
                          		 21734 - 31642 (+) enoyl hydratase/isomerase/PKS
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                            • AAS98782.1
                            		 31659 - 36752 (+) PKS
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                              • AAS98783.1
                              		 36820 - 48627 (+) PKS/NRPS
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                                • AAS98784.1
                                		 48697 - 51696 (+) PKS
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                                  • AAS98785.1
                                  		 51811 - 53277 (+) PKS
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                                    • AAS98786.1
                                    		 53274 - 56750 (+) NRPS
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                                      • AAS98787.1
                                      		 56771 - 62197 (+) PKS/TE
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                                        • AAS98788.1
                                        		 62318 - 63646 (-) cyclization
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                                          • AAS98789.1
                                          		 64050 - 64766 (-) hypothetical protein
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                                            • AAS98790.1
                                            		 64894 - 65517 (-) putative transposase
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                                              • AAS98792.1
                                              		 66175 - 66621 (-) hypothetical protein
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                                                • AAS98791.1
                                                		 67688 - 68833 (-) choloylglycine hydrolase-like protein
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                                                  • AAS98793.1
                                                  		 68839 - 69279 (-) hypothetical protein
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                                                    Biosynthesis information

                                                    Biosynthetic modules

                                                    Name
                                                    Unk01
                                                    Type
                                                    nrps-type1
                                                    Genes
                                                    AAS98786.1
                                                    Substrates
                                                    alanine (evidence: )
                                                    Integrated Monomers
                                                    Domains
                                                    adenylation
                                                    Annotation changelog

                                                    Entry version: 5

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2024-06-11
                                                    MIBiG v4 annotathon
                                                    • (ID: NHJ6M55E7ZEHUFNMEG4QIZWY)
                                                    • (ID: B54ZPFB4PBVBWY2K6JZNBOD5)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 4

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-10-07
                                                    Update chemical activity to schema version 2.11
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 3

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-09-15
                                                    Removed gene names of 'No gene ID'
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2022-09-15
                                                    Updated bioactivity data
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2022-09-15
                                                    Added NRP substrate specificities
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 2

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2019-10-16
                                                    Migrated from v1.4
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2019-10-16
                                                    Updated compound(s) information (NPAtlas curation)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 1

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2015-06-12
                                                    Submitted
                                                    • (ID: 5P6FUCFK6SYJZTN7O5IL377F)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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                                                    Identity
                                                    Coverage
                                                    Detailed domain annotation
                                                    Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
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