BGC0001099: kalimantacin A biosynthetic gene cluster from Pseudomonas fluorescens
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Location: 1 - 77,317 nt. (total: 77,317 nt).
This entry is originally from NCBI GenBank GU479979.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001099
Short description kalimantacin A biosynthetic gene cluster from Pseudomonas fluorescens
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Type I)
Loci
GU479979.1
via Knock-out studies
Compounds
  • kalimantacin A
Species Pseudomonas fluorescens [taxonomy]
References
Chemical products information
kalimantacin A Evidence:
Copy SMILES
C30H48N2O7
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADD82939.1
  • bat1
 1 - 6720 (+) Bat1
  • Scaffold biosynthesis
  • Knock-out
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  • ADD82940.1
  • bat2
 6732 - 30773 (+) Bat2
  • Scaffold biosynthesis
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  • ADD82941.1
  • bat3
 30833 - 46282 (+) Bat3
  • Scaffold biosynthesis
  • Knock-out
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  • ADD82942.1
  • batA
 46406 - 46660 (+) BatA
  • Tailoring
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  • ADD82943.1
  • batB
 46650 - 47867 (+) BatB
  • Tailoring
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  • ADD82944.1
  • batC
 47898 - 49160 (+) BatC
  • Tailoring
  • Knock-out
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  • ADD82945.1
  • batD
 49148 - 49924 (+) BatD
  • Tailoring
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  • ADD82946.1
  • batE
 49921 - 50673 (+) BatE
  • Tailoring
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  • ADD82947.1
  • batF
 50799 - 52547 (+) BatF
  • Tailoring
  • Knock-out
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  • ADD82948.1
  • batG
 52666 - 53856 (+) BatG
  • Resistance/immunity
  • Knock-out Heterologous expression
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  • ADD82949.1
  • batH
 53976 - 54941 (+) BatH
  • Scaffold biosynthesis
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  • ADD82950.1
  • batI
 54935 - 55732 (+) BatI
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    • ADD82951.1
    • batJ
    		 55760 - 56626 (+) BatJ
    • Scaffold biosynthesis
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    • ADD82952.1
    • batK
    		 56666 - 58042 (+) BatK
    • Tailoring
    • Knock-out
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    • ADD82953.1
    • batL
    		 58092 - 60257 (+) BatL
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      • ADD82954.1
      • batM
      		 60289 - 61224 (+) BatM
      • Activation / processing
      • Knock-out
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      • ADD82955.1
      • batN
      		 62127 - 62894 (+) BatN
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        • ADD82956.1
        • batO
        		 62905 - 63216 (+) BatO
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          • ADD82957.1
          • batP
          		 63213 - 65792 (+) BatP
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            • ADD82958.1
            • batQ
            		 65850 - 67301 (+) BatQ
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              • ADD82959.1
              • batR
              		 67312 - 68625 (+) BatR
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                • ADD82960.1
                • batS
                		 68666 - 70339 (+) BatS
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                  • ADD82961.1
                  • batT
                  		 70356 - 71141 (+) BatT
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                    • ADD82962.1
                    • batU
                    		 71161 - 72189 (+) BatU
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                      • ADD82963.1
                      • batV
                      		 72206 - 73342 (+) BatV
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                        • ADD82964.1
                        • batW
                        		 73335 - 74156 (+) BatW
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                          • ADD82965.1
                          • batX
                          		 74159 - 74416 (+) BatX
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                            • ADD82966.1
                            • batY
                            		 74516 - 76252 (+) BatY
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                              • ADD82967.1
                              • batZ
                              		 76274 - 77317 (+) BatZ
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                                Biosynthesis information

                                Biosynthetic modules

                                Name
                                2
                                Type
                                nrps-type1
                                Genes
                                bat2
                                Substrates
                                glycine (evidence: Structure-based inference)
                                Integrated Monomers
                                Domains
                                condensation, adenylation
                                Name
                                0
                                Type
                                pks-trans-at-starter
                                Genes
                                bat1
                                Substrates
                                Integrated Monomers
                                Domains
                                carrier (ACP)
                                Name
                                1
                                Type
                                pks-trans-at
                                Genes
                                bat1
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, ketoreductase, methyltransferase, carrier (ACP)
                                Name
                                3
                                Type
                                pks-trans-at
                                Genes
                                bat2
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, ketoreductase, carrier (ACP)
                                Name
                                4
                                Type
                                pks-trans-at
                                Genes
                                bat2
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, ketoreductase, carrier (ACP)
                                Name
                                5
                                Type
                                pks-trans-at
                                Genes
                                bat2
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, carrier (ACP)
                                Name
                                6
                                Type
                                pks-trans-at
                                Genes
                                bat2
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, ketoreductase, dehydratase, carrier (ACP)
                                Name
                                7
                                Type
                                pks-trans-at
                                Genes
                                bat2
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, ketoreductase, dehydratase, carrier (ACP)
                                Name
                                8
                                Type
                                pks-trans-at
                                Genes
                                bat3
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, ketoreductase, dehydratase, carrier (ACP)
                                Name
                                9
                                Type
                                pks-trans-at
                                Genes
                                bat3
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, carrier (ACP)
                                Name
                                10
                                Type
                                pks-trans-at
                                Genes
                                bat3
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, carrier (ACP)
                                Name
                                11
                                Type
                                pks-trans-at
                                Genes
                                bat3
                                Substrates
                                Integrated Monomers
                                Domains
                                ketosynthase, carrier (ACP)
                                Annotation changelog

                                Entry version: 4

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-10-07
                                Update chemical activity to schema version 2.11
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 3

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-09-15
                                Corrected NRP module activity
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2022-09-15
                                Corrected polyketide synthase gene entries
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2022-09-15
                                Removed ketoreductase stereochemistry annotation from modules without ketoreductases
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2022-09-15
                                Fix trans AT gene IDs
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2022-09-15
                                Cleaned up synonym list
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2022-09-15
                                Changed amino acid substrates to lower case
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 2

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2019-10-16
                                Migrated from v1.4
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2019-10-16
                                Updated compound(s) information (NPAtlas curation)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 1

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2015-06-12
                                Submitted
                                • (ID: LBLIPTLAGFUPCXL63ODXWSCG)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                Detailed domain annotation
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