BGC0001103: mycosubtilin biosynthetic gene cluster from Bacillus subtilis subsp. spizizenii ATCC 6633
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Location: 1 - 46,860 nt. (total: 46,860 nt).
This entry is originally from NCBI GenBank AF184956.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001103
Short description mycosubtilin biosynthetic gene cluster from Bacillus subtilis subsp. spizizenii ATCC 6633
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: AF184956.1
Compounds
  • mycosubtilin
Species Bacillus subtilis subsp. spizizenii ATCC 6633 [taxonomy]
References
Chemical products information
mycosubtilin
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C55H86N14O16
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAF08794.1
  • fenF
 1938 - 3140 (+) FenF
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  • AAF08795.1
  • mycA
 3161 - 15076 (+) MycA
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  • AAF08796.1
  • mycB
 15133 - 31242 (+) MycB
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  • AAF08797.1
  • mycC
 31340 - 39169 (+) MycC
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  • AAF08798.1
  • yngL
 39339 - 39731 (+) YngL
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  • AAF08799.1
  • yngK
 39886 - 41418 (+) YngK
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  • AAF08800.1
  • yngJ
 41925 - 43067 (+) YngJ
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  • AAF08801.1
  • yngI
 43110 - 44759 (+) YngI
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  • AAF08802.1
  • yngH
 44769 - 46103 (+) YngH
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  • AAF08803.1
  • yngXX
 46118 - 46339 (+) YngXX
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
mycA
Module ?
Specificity: asparagine
Evidence for specificity:
mycB
Module ?
Specificity: tyrosine
Evidence for specificity:
Module ?
Specificity: asparagine
Evidence for specificity:
Module ?
Specificity: glutamine
Evidence for specificity:
Module ?
Specificity: proline
Evidence for specificity:
mycC
Module ?
Specificity: serine
Evidence for specificity:
Module ?
Specificity: asparagine
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: 5UL74VURKJ25VSPPPO3H2NYB, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update compound structure (SMILES) for mycosubtilin
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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