BGC0001114: thailanstatin A biosynthetic gene cluster from Burkholderia thailandensis
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Location: 1 - 85,738 nt. (total: 85,738 nt).
This entry is originally from NCBI GenBank JX307851.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001114
Short description thailanstatin A biosynthetic gene cluster from Burkholderia thailandensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: JX307851.1
Compounds
  • thailanstatin A
Species Burkholderia thailandensis [taxonomy]
References
Chemical products information
thailanstatin A
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C28H41N1O9
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AGN11877.1
 1 - 576 (-) putative transcriptional regulator
  • Regulation
Sequence-based prediction
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  • AGN11878.1
 692 - 2299 (-) putative alkyl hydroperoxide reductase subunit F
  • Unknown
Sequence-based prediction
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  • AGN11879.1
 2440 - 3003 (-) putative alkyl hydroperoxide reductase subunit C
  • Unknown
Sequence-based prediction
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  • AGN11896.1
  • tstA
 3438 - 4268 (-) tstA
  • Scaffold biosynthesis
Sequence-based prediction
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  • AGN11880.1
  • tstC
 7401 - 22394 (+) tstC
  • Scaffold biosynthesis
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  • AGN11881.1
  • tstDEF
 22470 - 46580 (+) tstDEF
  • Scaffold biosynthesis
Sequence-based prediction
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  • AGN11882.1
  • tstGH
 46637 - 61204 (+) tstGH
  • Scaffold biosynthesis
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  • AGN11883.1
  • tstI
 61206 - 70391 (+) tstI
  • Scaffold biosynthesis
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  • AGN11884.1
  • tstJ
 70459 - 71343 (+) tstJ
  • Scaffold biosynthesis
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  • AGN11885.1
  • tstK
 71363 - 72652 (+) tstK
  • Precursor biosynthesis
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  • AGN11886.1
  • tstL
 72640 - 73425 (+) tstL
  • Scaffold biosynthesis
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  • AGN11887.1
  • tstM
 73480 - 73719 (+) tstM
  • Scaffold biosynthesis
Sequence-based prediction
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  • AGN11888.1
  • tstN
 73706 - 74974 (+) tstN
  • Scaffold biosynthesis
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  • AGN11889.1
  • tstO
 74980 - 76158 (+) tstO
  • Scaffold biosynthesis
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  • AGN11890.1
  • tstB
 76246 - 77214 (+) tstB
  • Scaffold biosynthesis
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  • AGN11891.1
  • tstR
 77826 - 79274 (-) tstR
  • Tailoring (Oxidation)
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  • AGN11892.1
  • tstQ
 79931 - 80368 (-) tstQ
  • Tailoring (Unknown)
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  • AGN11893.1
  • tstP
 80514 - 81539 (-) tstP
  • Tailoring (Oxidation)
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  • AGN11894.1
 82628 - 83413 (+) TrpC indole-3-glycerol phosphate synthase
  • Unknown
Sequence-based prediction
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  • AGN11895.1
 83705 - 85738 (+) ExoU type III effector protein
  • Unknown
Sequence-based prediction
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
tstDEF
Module ?
Specificity: threonine
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: DUUOEWRWRZA5NTLPQCYGT6Z6, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Removed gene names of 'No gene ID'
  • Removed duplicated gene identifier
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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