BGC0001114: thailanstatin A biosynthetic gene cluster from Burkholderia thailandensis
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Location: 1 - 85,738 nt. (total: 85,738 nt).
This entry is originally from NCBI GenBank JX307851.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001114
Short description thailanstatin A biosynthetic gene cluster from Burkholderia thailandensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
JX307851.1
via
Compounds
  • thailanstatin A
Species Burkholderia thailandensis [taxonomy]
References
Chemical products information
thailanstatin A Evidence:
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C28H41N1O9
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AGN11877.1
 1 - 576 (-) putative transcriptional regulator
  • Regulation
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  • AGN11878.1
 692 - 2299 (-) putative alkyl hydroperoxide reductase subunit F
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    • AGN11879.1
    		 2440 - 3003 (-) putative alkyl hydroperoxide reductase subunit C
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      • AGN11896.1
      • tstA
      		 3438 - 4268 (-) tstA
      • Scaffold biosynthesis
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      • AGN11880.1
      • tstC
      		 7401 - 22394 (+) tstC
      • Scaffold biosynthesis
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      • AGN11881.1
      • tstDEF
      		 22470 - 46580 (+) tstDEF
      • Scaffold biosynthesis
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      • AGN11882.1
      • tstGH
      		 46637 - 61204 (+) tstGH
      • Scaffold biosynthesis
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      • AGN11883.1
      • tstI
      		 61206 - 70391 (+) tstI
      • Scaffold biosynthesis
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      • AGN11884.1
      • tstJ
      		 70459 - 71343 (+) tstJ
      • Scaffold biosynthesis
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      • AGN11885.1
      • tstK
      		 71363 - 72652 (+) tstK
      • Precursor biosynthesis
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      • AGN11886.1
      • tstL
      		 72640 - 73425 (+) tstL
      • Scaffold biosynthesis
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      • AGN11887.1
      • tstM
      		 73480 - 73719 (+) tstM
      • Scaffold biosynthesis
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      • AGN11888.1
      • tstN
      		 73706 - 74974 (+) tstN
      • Scaffold biosynthesis
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      • AGN11889.1
      • tstO
      		 74980 - 76158 (+) tstO
      • Scaffold biosynthesis
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      • AGN11890.1
      • tstB
      		 76246 - 77214 (+) tstB
      • Scaffold biosynthesis
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      • AGN11891.1
      • tstR
      		 77826 - 79274 (-) tstR
      • Tailoring
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      • AGN11892.1
      • tstQ
      		 79931 - 80368 (-) tstQ
      • Tailoring
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      • AGN11893.1
      • tstP
      		 80514 - 81539 (-) tstP
      • Tailoring
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      • AGN11894.1
      		 82628 - 83413 (+) TrpC indole-3-glycerol phosphate synthase
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        • AGN11895.1
        		 83705 - 85738 (+) ExoU type III effector protein
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          Biosynthesis information

          Biosynthetic modules

          Name
          Unk01
          Type
          nrps-type1
          Genes
          tstDEF
          Substrates
          threonine (evidence: )
          Integrated Monomers
          Domains
          adenylation
          Annotation changelog

          Entry version: 4

          Date
          Changes
          Submitters
          Reviewers
          2022-10-07
          Update chemical activity to schema version 2.11
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 3

          Date
          Changes
          Submitters
          Reviewers
          2022-09-15
          Removed gene names of 'No gene ID'
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Removed duplicated gene identifier
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2022-09-15
          Added NRP substrate specificities
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 2

          Date
          Changes
          Submitters
          Reviewers
          2019-10-16
          Migrated from v1.4
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          2019-10-16
          Updated compound(s) information (NPAtlas curation)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

          Entry version: 1

          Date
          Changes
          Submitters
          Reviewers
          2015-06-12
          Submitted
          • (ID: DUUOEWRWRZA5NTLPQCYGT6Z6)
          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
          Detailed domain annotation
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