BGC0001115: thiomarinol biosynthetic gene cluster from Pseudoalteromonas sp. SANK 73390
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Location: 1 - 97,600 nt. (total: 97,600 nt).
This entry is originally from NCBI GenBank FN689524.1.

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core biosynthetic genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001115
Short description thiomarinol biosynthetic gene cluster from Pseudoalteromonas sp. SANK 73390
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
FN689524.1
10748 - 97600
via
Compounds
  • thiomarinol
Species Pseudoalteromonas sp. SANK 73390 [taxonomy]
References
Chemical products information
thiomarinol Evidence:
Copy SMILES
C30H44N2O9S2
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CBK62717.1
  • tacpB
 10748 - 11083 (-)
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    • CBK62718.1
    • tmpF
    		 11086 - 13338 (-)
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      • CBK62719.1
      • tacpD
      		 13493 - 13828 (-)
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        • CBK62720.1
        • tmlS
        		 13822 - 14547 (-)
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          • CBK62721.1
          • tmlQ
          		 14561 - 15898 (-)
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            • CBK62722.1
            • tmlM
            		 16377 - 19523 (-)
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              • CBK62723.1
              • tmlA
              		 20098 - 21222 (+)
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                • CBK62724.1
                • tmpA
                		 21265 - 30297 (+)
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                  • CBK62725.1
                  • tacpC
                  		 30294 - 30560 (+)
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                    • CBK62726.1
                    • tmlG
                    		 30562 - 31779 (+)
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                      • CBK62727.1
                      • tmlH
                      		 31803 - 33068 (+)
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                        • CBK62728.1
                        • tmlJ
                        		 33091 - 33858 (+)
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                          • CBK62729.1
                          • tmpE
                          		 33858 - 38192 (+)
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                            • CBK62730.1
                            • tmlL
                            		 38189 - 39022 (+)
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                              • CBK62731.1
                              • tmpB
                              		 39136 - 47388 (+)
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                                • CBK62732.1
                                • tmpC
                                		 47452 - 50805 (+)
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                                  • CBK62733.1
                                  • tmpD
                                  		 50878 - 70959 (+)
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                                    • CBK62734.1
                                    • tmlB
                                    		 71058 - 71981 (+)
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                                      • CBK62735.1
                                      • tmlC
                                      		 72078 - 73217 (+)
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                                        • CBK62736.1
                                        • tmlF
                                        		 73267 - 74319 (+)
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                                          • CBK62737.1
                                          • tmlP
                                          		 74316 - 75236 (-)
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                                            • CBK62738.1
                                            • tmlO
                                            		 75246 - 76598 (-) cytochrome P450
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                                              • CBK62739.1
                                              • tmlU
                                              		 76680 - 78644 (-)
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                                                • CBK62740.1
                                                • tmlY
                                                		 78712 - 79242 (-)
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                                                  • CBK62741.1
                                                  • tmuA
                                                  		 79587 - 80669 (-)
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                                                    • CBK62742.1
                                                    • tacpA
                                                    		 81681 - 81962 (+)
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                                                      • CBK62743.1
                                                      • tmuB
                                                      		 82295 - 83089 (+)
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                                                        • CBK62744.1
                                                        • tmlW
                                                        		 83143 - 84546 (+)
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                                                          • CBK62745.1
                                                          • tmlZ
                                                          		 84558 - 84941 (+)
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                                                            • CBK62746.1
                                                            • holA
                                                            		 85410 - 88778 (+)
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                                                              • CBK62747.1
                                                              • holB
                                                              		 88790 - 90415 (+)
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                                                                • CBK62748.1
                                                                • holC
                                                                		 90412 - 91155 (+)
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                                                                  • CBK62749.1
                                                                  • holD
                                                                  		 91174 - 92310 (+)
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                                                                    • CBK62750.1
                                                                    • holE
                                                                    		 92330 - 93214 (+)
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                                                                      • CBK62751.1
                                                                      • holF
                                                                      		 93255 - 93719 (+)
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                                                                        • CBK62752.1
                                                                        • holG
                                                                        		 93773 - 94363 (+)
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                                                                          • CBK62753.1
                                                                          • holH
                                                                          		 94447 - 97557 (+)
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                                                                            Biosynthesis information

                                                                            Biosynthetic modules

                                                                            Name
                                                                            Unk01
                                                                            Type
                                                                            nrps-type1
                                                                            Genes
                                                                            holA
                                                                            Substrates
                                                                            cysteine (evidence: Structure-based inference, Sequence-based prediction, Knock-out studies)
                                                                            Integrated Monomers
                                                                            Domains
                                                                            adenylation
                                                                            Annotation changelog

                                                                            Entry version: 4

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2022-10-07
                                                                            Update chemical activity to schema version 2.11
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 3

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2022-09-15
                                                                            Updated bioactivity data
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            2022-09-15
                                                                            Added NRP substrate specificities
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 2

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2019-10-16
                                                                            Migrated from v1.4
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            2019-10-16
                                                                            Updated compound(s) information (NPAtlas curation)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 1

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2015-06-12
                                                                            Submitted
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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