divK + divL3 + divL1 + divM + divL2
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Synthase subclass: Modular type I
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Module 0
Genes: divK
Core domains: Ketoreductase, CoA-ligase, Thiolation (ACP/PCP)
KR-domain stereochemistry: Inactive
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Module 1
Specificity: Methylmalonyl-CoA
Evidence for specificity: Sequence-based prediction
Genes: divK
Core domains: Ketosynthase, Acyltransferase, Ketoreductase, Dehydratase, Thiolation (ACP/PCP)
KR-domain stereochemistry: L-OH
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Module 2
Specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
Genes: divK
Core domains: Ketosynthase, Acyltransferase, Thiolation (ACP/PCP)
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Module 3
Specificity: Malonyl-CoA
Genes: divK
Core domains: Ketosynthase, Acyltransferase, Ketoreductase, Thiolation (ACP/PCP)
KR-domain stereochemistry: D-OH
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Module 4
Specificity: Ethylmalonyl-CoA
Evidence for specificity: Sequence-based prediction
Genes: divL1
Core domains: Ketosynthase, Acyltransferase, Ketoreductase, Dehydratase, Enoylreductase, Thiolation (ACP/PCP)
KR-domain stereochemistry: L-OH
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Module 5
Specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
Genes: divL2
Core domains: Ketosynthase, Acyltransferase, Ketoreductase, Dehydratase, Thiolation (ACP/PCP)
KR-domain stereochemistry: L-OH
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Module 6
Genes: divL3
Core domains: Ketosynthase, Acyltransferase, Ketoreductase, Dehydratase, Enoylreductase, Thiolation (ACP/PCP)
KR-domain stereochemistry: L-OH
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Module 7
Specificity: Methylmalonyl-CoA
Evidence for specificity: Sequence-based prediction
Genes: divM
Core domains: Ketosynthase, Acyltransferase, Thiolation (ACP/PCP)
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Module 8
Specificity: Malonyl-CoA
Evidence for specificity: Sequence-based prediction
Genes: divM
Core domains: Ketosynthase, Acyltransferase, Ketoreductase, Dehydratase, Thiolation (ACP/PCP)
KR-domain stereochemistry: L-OH
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