BGC0001179: rishirilide B biosynthetic gene cluster from Streptomyces bottropensis
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 46,538 nt. (total: 46,538 nt).
This entry is originally from NCBI GenBank KJ437438.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001179
Short description rishirilide B biosynthetic gene cluster from Streptomyces bottropensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type II)
Loci
KJ437438.1
via Heterologous expression
Compounds
  • rishirilide B
  • rishirilide A
Species Streptomyces bottropensis [taxonomy]
References
Chemical products information
rishirilide B Evidence:
Copy SMILES
C21H24O6
rishirilide A Evidence:
Copy SMILES
C42H48O13
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AHL46707.1
  • rslC1
 11304 - 12251 (+) putative cyclase/aromatase
    copy AA seq
    copy Nt seq
    • AHL46708.1
    • rslK1
    		 12314 - 12583 (-) acyl carrier protein
      copy AA seq
      copy Nt seq
      • AHL46709.1
      • rslK2
      		 12677 - 13903 (-) ketosynthase
        copy AA seq
        copy Nt seq
        • AHL46710.1
        • rslK3
        		 13900 - 15168 (-) ketosynthase
          copy AA seq
          copy Nt seq
          • AHL46711.1
          • rslA
          		 15177 - 16208 (-) acyltransferase
            copy AA seq
            copy Nt seq
            • AHL46712.1
            • rslK4
            		 16578 - 17639 (+) ketosynthase
              copy AA seq
              copy Nt seq
              • AHL46713.1
              • rslT1
              		 17766 - 18731 (-) ABc transporter protein
                copy AA seq
                copy Nt seq
                • AHL46714.1
                • rslT2
                		 18842 - 19591 (-) ABc transporter protein
                  copy AA seq
                  copy Nt seq
                  • AHL46715.1
                  • rslT3
                  		 19588 - 20547 (-) ABc transporter protein
                    copy AA seq
                    copy Nt seq
                    • AHL46716.1
                    • rslO1
                    		 20562 - 21626 (-) luciferase-like monooxygenase
                      copy AA seq
                      copy Nt seq
                      • AHL46717.1
                      • rslO2
                      		 21694 - 22212 (-) flavin reductase
                        copy AA seq
                        copy Nt seq
                        • AHL46718.1
                        • rslP
                        		 22239 - 23366 (-) putative phosphotransferase
                          copy AA seq
                          copy Nt seq
                          • AHL46719.1
                          • rslR1
                          		 23380 - 24189 (-) SARP regulatory protein
                            copy AA seq
                            copy Nt seq
                            • AHL46720.1
                            • rslC2
                            		 24320 - 25225 (+) putative cyclase
                              copy AA seq
                              copy Nt seq
                              • AHL46721.1
                              • rslO3
                              		 25431 - 26147 (+) ketoreductase
                                copy AA seq
                                copy Nt seq
                                • AHL46722.1
                                • rslO4
                                		 26214 - 26516 (-) Monooxygenase
                                • Monooxygenation
                                copy AA seq
                                copy Nt seq
                                • AHL46723.1
                                • rslO5
                                		 26595 - 27686 (-) oxidoreductase
                                  copy AA seq
                                  copy Nt seq
                                  • AHL46724.1
                                  • rslC3
                                  		 27683 - 28168 (-) putative cyclase/aromatase
                                    copy AA seq
                                    copy Nt seq
                                    • AHL46725.1
                                    • rslR2
                                    		 28286 - 29110 (-) SARP regulatory protein
                                      copy AA seq
                                      copy Nt seq
                                      • AHL46726.1
                                      • rslR3
                                      		 29329 - 32667 (-) SARP regulatory protein
                                        copy AA seq
                                        copy Nt seq
                                        • AHL46727.1
                                        • rslO6
                                        		 32727 - 33755 (-) luciferase-like monooxygenase
                                          copy AA seq
                                          copy Nt seq
                                          • AHL46728.1
                                          • rslR4
                                          		 33801 - 34262 (-) putative transcriptional regulator
                                            copy AA seq
                                            copy Nt seq
                                            • AHL46729.1
                                            • rslT4
                                            		 34510 - 36048 (+) transporter protein
                                              copy AA seq
                                              copy Nt seq
                                              • AHL46730.1
                                              • rslO7
                                              		 36261 - 37157 (+) oxidoreductase
                                                copy AA seq
                                                copy Nt seq
                                                • AHL46731.1
                                                • rslO8
                                                		 37223 - 38200 (+) oxidoreductase
                                                  copy AA seq
                                                  copy Nt seq
                                                  • AHL46732.1
                                                  • rslO9
                                                  		 38319 - 39920 (+) FAD dependent monooxygenase
                                                    copy AA seq
                                                    copy Nt seq
                                                    • AHL46733.1
                                                    • rslO10
                                                    		 39981 - 40796 (+) ketoreductase
                                                      copy AA seq
                                                      copy Nt seq
                                                      • AHL46734.1
                                                      • rslH
                                                      		 40810 - 42108 (+) putative amidohydrolase
                                                        copy AA seq
                                                        copy Nt seq
                                                        Biosynthesis information

                                                        No biosynthesis information available for this record.

                                                        Annotation changelog

                                                        Entry version: 5

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2024-05-14
                                                        MIBiG v4 annotathon
                                                        • (ID: T3MMYN6KH4YYZE7LB25SN426)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 4

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2022-10-07
                                                        Update chemical activity to schema version 2.11
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 3

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2022-09-15
                                                        Updated bioactivity data
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 2

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2019-10-16
                                                        Migrated from v1.4
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 1

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2015-06-12
                                                        Submitted
                                                        • (ID: LPHAMZXQ3BT6INJWOLKUYGWU)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        Similar known clusters from MIBiG 4.0
                                                        Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                        Detailed help and explanations are available here.

                                                        Click on reference genes to show details of similarities to genes within the current region.
                                                        Double click on a reference drawing to reverse the display of the genes.

                                                        Click on an accession to open that entry in the MIBiG database.


                                                        Location:

                                                        Identifier
                                                        Identity
                                                        Coverage
                                                        Detailed domain annotation
                                                        Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                        A domain glossary is available here, and an explanation of the visualisation is available here.
                                                        Selected features only
                                                        Show module domains