BGC0001197: frankiamicin biosynthetic gene cluster from Frankia sp. EAN1pec
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Location: 2,838,708 - 2,851,386 nt. (total: 12,679 nt).
This entry is originally from NCBI GenBank CP000820.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001197
Short description frankiamicin biosynthetic gene cluster from Frankia sp. EAN1pec
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
CP000820.1
2838708 - 2851386
via
Compounds
  • frankiamicin
Species Frankia sp. EAN1pec [taxonomy]
References
Chemical products information
frankiamicin Evidence:
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C24H16O9
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • Franean1_2384
  • ABW11816.1
 2838708 - 2842106 (+) integral membrane sensor signal transduction histidine kinase
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    • Franean1_2385
    • ABW11817.1
    		 2842106 - 2842525 (+) Roadblock/LC7 family protein
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      • Franean1_2386
      • ABW11818.1
      		 2842643 - 2843014 (+) protein of unknown function DUF742
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        • Franean1_2387
        • ABW11819.1
        		 2842995 - 2843618 (+) protein of unknown function ATP binding
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          • Franean1_2388
          • ABW11820.1
          		 2843681 - 2844679 (+) transcriptional regulator, LuxR family
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            • Franean1_2389
            • ABW11821.1
            		 2845012 - 2845389 (+) Polyketide synthesis cyclase
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              • Franean1_2390
              • ABW11822.1
              		 2845790 - 2846047 (+) putative actinorhodin polyketide synthase acyl carrier protein (ACP) (ActI ORF3)
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                • Franean1_2391
                • ABW11823.1
                		 2846098 - 2846592 (+) cyclase/dehydrase
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                  • Franean1_2392
                  • ABW11824.1
                  		 2846603 - 2847025 (+) Cupin 2 conserved barrel domain protein
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                    • Franean1_2393
                    • ABW11825.1
                    		 2847022 - 2848374 (+) Beta-ketoacyl synthase
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                      • Franean1_2394
                      • ABW11826.1
                      		 2848371 - 2849657 (+) Beta-ketoacyl synthase
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                        • Franean1_2395
                        • ABW11827.1
                        		 2849760 - 2850497 (+) short-chain dehydrogenase/reductase SDR
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                          • Franean1_2396
                          • ABW11828.1
                          		 2850497 - 2850820 (+) Antibiotic biosynthesis monooxygenase
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                            • Franean1_2397
                            • ABW11829.1
                            		 2850937 - 2851386 (+) Antibiotic biosynthesis monooxygenase
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                              Biosynthesis information
                              Annotation changelog

                              Entry version: 4

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-10-07
                              Update chemical activity to schema version 2.11
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 3

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2022-09-15
                              Updated bioactivity data
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 2

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2019-10-16
                              Migrated from v1.4
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              2019-10-16
                              Updated compound(s) information (MIBiG Annotathon)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 1

                              Date
                              Changes
                              Submitters
                              Reviewers
                              2015-08-17
                              Submitted
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              Detailed domain annotation
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