BGC0001277: nivalenol biosynthetic gene cluster from Fusarium graminearum
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Location: 1 - 57,840 nt. (total: 57,840 nt).
This entry is originally from NCBI GenBank AF359361.3.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001277
Short description nivalenol biosynthetic gene cluster from Fusarium graminearum
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Terpene
Loci NCBI GenBank: AF359361.3
Compounds
  • nivalenol
  • vomitoxin
  • 3-acetyldeoxynivalenol
  • 15-acetyldeoxynivalenol
  • neosolaniol
  • calonectrin
  • apotrichodiol
  • isotrichotriol
  • 15-deacetylcalonectrin
  • T-2 toxin
  • 3-acetyl T-2 toxin
  • trichodiene
Species Fusarium graminearum [taxonomy]
References
Chemical products information
nivalenol
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C15H20O7
Chemical database entries
PubCHEM
vomitoxin
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C15H20O6
Chemical database entries
NPAtlas
3-acetyldeoxynivalenol
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C17H22O7
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PubCHEM
15-acetyldeoxynivalenol
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C17H22O7
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PubCHEM
neosolaniol
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C19H26O8
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PubCHEM
calonectrin
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C19H26O6
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PubCHEM
apotrichodiol
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C15H24O3
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PubCHEM
isotrichotriol
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C15H24O4
Chemical database entries
PubCHEM
15-deacetylcalonectrin
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C17H24O5
Chemical database entries
NPAtlas
T-2 toxin
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C24H34O9
Chemical database entries
PubCHEM
3-acetyl T-2 toxin
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C27H38O10
Chemical database entries
PubCHEM
trichodiene
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C15H24
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAO34671.1
  • OrfF
 622 - 1784 (+) methyltransferase
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  • AAO34672.1
  • OrfE
 2146 - 3213 (-) unknown
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  • AAO34673.1
  • OrfD
 6811 - 9974 (+) unknown
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  • AAO34674.1
  • OrfC
 10155 - 11114 (-) glucosidase
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  • AAO34675.1
  • OrfB
 12533 - 13307 (+) acetylesterase
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  • AAO34676.1
  • OrfA
 13429 - 14546 (-) monooxygenase
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  • AAK33086.1
  • TRI8
 17555 - 18892 (-) TRI8
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  • AAK33082.2
  • TRI3
 21770 - 23537 (+) putative 15-O-acetyltransferase
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  • AAK33083.1
  • TRI4
 24491 - 26232 (-) putative cytochrome P450
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  • AAK33085.1
  • TRI6
 27401 - 28057 (+) positive regulatory protein
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  • AAK33084.1
  • TRI5
 30945 - 32131 (+) trichodiene synthase
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  • AAK33079.1
  • TRI10
 32799 - 34151 (+) TRI10
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  • AAK33087.1
  • TRI9
 34747 - 34878 (-) TRI9
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  • AAK33080.1
  • TRI11
 36046 - 37786 (-) putative trichothecene C-15 hydroxylase
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  • AAK33081.1
  • TRI12
 38344 - 40320 (-) trichothecene efflux pump
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  • AAN40836.1
  • TRI14
 43400 - 44569 (+) unknown
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  • AAO34677.1
  • OrfG
 45216 - 45964 (-) deacetylase
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  • AAO34678.1
  • OrfH
 49155 - 51000 (+) unknown
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  • AAO34679.1
  • OrfI
 51292 - 52146 (-) dehydrogenase
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  • AAO34680.1
  • OrfJ
 52790 - 54210 (-) reductase
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  • AAO34681.1
  • OrfK
 55250 - 56803 (+) monooxygenase
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  • AAO34682.1
  • OrfL
 57076 - 57840 (+) catalase
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Annotation changelog
MIBiG version Submitter Notes
1.2
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Cleaned up synonym list
Similar known gene clusters
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