BGC0001278: nivalenol biosynthetic gene cluster from Fusarium sporotrichioides
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Location: 1 - 54,488 nt. (total: 54,488 nt).
This entry is originally from NCBI GenBank AF359360.3, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0001278
Short description nivalenol biosynthetic gene cluster from Fusarium sporotrichioides
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Terpene
Loci NCBI GenBank: AF359360.3
Compounds
  • nivalenol
  • deoxynivalenol
  • 3-acetyldeoxynivalenol
  • 15-acetyldeoxynivalenol
  • neosolaniol
  • calonectrin
  • apotrichodiol
  • isotrichotriol
  • 15-decalonectrin
  • T-2 toxin
  • 3-acetyl T-2 toxin
  • trichodiene
Species Fusarium sporotrichioides [taxonomy]
References
Chemical products information
nivalenol
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C15H20O7
Chemical database entries
PubCHEM
deoxynivalenol
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C15H20O6
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PubCHEM
3-acetyldeoxynivalenol
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C17H22O7
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PubCHEM
15-acetyldeoxynivalenol
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C17H22O7
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PubCHEM
neosolaniol
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C19H26O8
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PubCHEM
calonectrin
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C19H26O6
Chemical database entries
PubCHEM
apotrichodiol
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C15H24O3
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PubCHEM
isotrichotriol
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C15H24O4
Chemical database entries
PubCHEM
15-decalonectrin
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C17H24O5
Chemical database entries
PubCHEM
T-2 toxin
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C24H34O9
Chemical database entries
PubCHEM
3-acetyl T-2 toxin
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C27H38O10
Chemical database entries
PubCHEM
trichodiene
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C15H24
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAO27746.2
  • OrfF
 589 - 1760 (+) putative methyltransferase
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  • AAO27747.1
  • OrfE
 2131 - 3198 (-) unknown
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  • AAO27748.1
  • OrfD
 4962 - 8121 (+) unknown
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  • AAO27749.1
  • OrfC
 8300 - 9260 (-) glucosidase
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  • AAO27750.1
  • OrfB
 10782 - 11555 (+) esterase
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  • AAO27751.1
  • OrfG
 12093 - 13209 (-) monooxygenase
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  • AAK33077.1
  • TRI8
 15488 - 16831 (-) Tri8
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  • AAK33076.1
  • TRI7
 17529 - 18907 (+) Tri7
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  • AAK33072.1
  • TRI3
 19674 - 21456 (+) 15-O-acetyltransferase
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  • AAK33073.1
  • TRI4
 22222 - 23964 (-) cytochrome P450
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  • AAK33075.1
  • TRI6
 25123 - 25776 (+) positive regulatory protein
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  • AAK33074.1
  • TRI5
 28080 - 29264 (+) trichodiene synthase
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  • AAK33069.1
  • TRI10
 29881 - 31220 (+) putative trichothecene biosynthetic gene
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  • AAK33078.1
  • TRI9
 31851 - 31982 (-) TRI9
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  • AAK33070.1
  • TRI11
 33069 - 34790 (-) trichothecene C-15 hydroxylase
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  • AAK33071.1
  • TRI12
 35435 - 37336 (-) trichothecene efflux pump
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  • AAN40834.1
  • TRI13
 38106 - 39938 (-) cytochrome P450
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  • AAN40835.1
  • TRI14
 40706 - 41881 (+) unknown
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  • AAO27752.1
  • OrfG_rename1
 42580 - 43337 (-) deacetylase
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  • AAO27753.1
  • OrfH
 44960 - 46803 (+) unknown
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  • AAO27754.1
  • OrfI
 47603 - 48460 (-) dehydrogenase
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  • AAO27755.1
  • OrfJ
 49404 - 50824 (-) reductase
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  • AAO27756.1
  • OrfK
 51884 - 53437 (+) monooxygenase
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  • AAO27757.1
  • OrfL
 53727 - >54488 (+) catalase
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Annotation changelog
MIBiG version Submitter Notes
1.2
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Cleaned up synonym list
Similar known gene clusters
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Modifications to original record
  • renamed CDS with name OrfG at join{[43032:43337](-), [42579:42967](-)} to OrfG_rename1 to avoid duplicates