BGC0001337: lazarimide A biosynthetic gene cluster from uncultured bacterium
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Location: 3,107 - 25,639 nt. (total: 22,533 nt).
This entry is originally from NCBI GenBank KR052816.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
Compounds
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001337
Short description lazarimide A biosynthetic gene cluster from uncultured bacterium
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Alkaloid (Indole/benzopyrrole)
Loci NCBI GenBank: KR052816.1
Compounds
  • lazarimide A
  • lazarimide B
  • lazarimide C
Species uncultured bacterium [taxonomy]
References
Chemical products information
lazarimide A [synonyms: lazarimide]
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C22H15Cl2N3O6
lazarimide B
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C22H15Cl2N3O5
lazarimide C
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C20H11Cl2N3O4
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AKQ20686.1
  • lzrX1a
 3107 - 3502 (-) monooxygenase
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  • AKQ20687.1
  • lzrX1b
 3436 - 4686 (-) monooxygenase
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  • AKQ20688.1
  • lzrM1
 4824 - 5516 (+) N-methyltransferase
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  • AKQ20689.1
  • lzrP
 5513 - 6697 (-) RebP-like cytochrome p450
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  • AKQ20690.1
  • lzrC
 6694 - 8361 (-) RebC-like monooxygenase
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  • AKQ20691.1
  • lzrY1
 8539 - 9303 (+) putative alpha/beta hydrolase
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  • AKQ20692.1
  • lzrY2
 9282 - 9509 (+) putative alpha/beta hydrolase
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  • AKQ20693.1
  • lzrF
 9575 - 10054 (-) putative flavin reductase
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  • AKQ20694.1
  • lzrT1
 10051 - 10545 (-) putative cation/H+ antiporter
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  • AKQ20695.1
  • lzrT2
 10503 - 11270 (-) putative cation/H+ antiporter
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  • AKQ20696.1
  • lzrH1
 11283 - 12821 (-) tryptophan-5 halogenase
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  • AKQ20697.1
  • lzrM3
 12858 - 13859 (-) O-methyltransferase
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  • AKQ20698.1
  • lzrX2
 13856 - 15109 (-) monooxygenase
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  • AKQ20699.1
  • lzrH2
 15114 - 16706 (-) tryptophan-6 halogenase
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  • AKQ20700.1
  • lzrO
 16907 - 18343 (+) RebO-like L-amino acid oxidase
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  • AKQ20701.1
  • lzrD
 18340 - 21273 (+) RebD-like chromopyrrolic acid synthase
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  • AKQ20702.1
  • lzrG
 21266 - 22363 (-) cytochrome p450
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  • AKQ20703.1
  • lzrR
 22796 - 25639 (-) LuxR-type transcriptional regulator
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Annotation changelog
MIBiG version Submitter Notes
1.3
  • Hidden contributor (ID: TFC7LOLNUCTKZCZQ4X3ELKJ7, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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