BGC0001436: cornexistin biosynthetic gene cluster from Paecilomyces divaricatus
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Location: 1 - 58,291 nt. (total: 58,291 nt).
This entry is originally from NCBI GenBank MF197864.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
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Biosynthesis
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KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001436
Short description cornexistin biosynthetic gene cluster from Paecilomyces divaricatus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Iterative type I)
Loci
MF197864.1
via Knock-out studies
Compounds
  • cornexistin
Species Paecilomyces divaricatus [taxonomy]
References
Chemical products information
cornexistin Evidence: NMR, Mass spectrometry, X-ray crystallography
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C16H20O6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ASK38699.1
  • pvL18
 26 - 3420 (+) putative nonribosomal peptide synthetase-like protein
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    • ASK38700.1
    • pvL17
    		 3962 - 4990 (+) putative fumarylacetoacetate hydrolase
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      • ASK38701.1
      • pvL16
      		 6530 - 7261 (-) hypothetical protein
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        • ASK38702.1
        • pvL15
        		 8347 - 9393 (-) putative aldo/keto reductase
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          • ASK38703.1
          • pvL14
          		 11449 - 13371 (+) putative transketolase
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            • ASK38704.1
            • pvL13
            		 14979 - 16613 (-) cytochrome P450
            • Tailoring
            • Knock-out
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            • ASK38705.1
            • pvL12
            		 17137 - 18645 (+) major facilitator superfamily transporter
            • Transport
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            • ASK38706.1
            • pvL11
            		 19894 - 20845 (-) dienelactone hydrolase
            • Tailoring
            • Knock-out
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            • ASK38707.1
            • pvL10
            		 21179 - 22777 (-) major facilitator superfamily transporter
            • Transport
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            • ASK38708.1
            • pvL9
            		 23323 - 25562 (+) putative serine carboxypeptidase
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              • ASK38709.1
              • pvL8
              		 25765 - 27237 (-) C6 transcription factor
              • Regulation
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              • ASK38710.1
              • pvL7
              		 28909 - 30039 (+) putative gluconolactonase
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                • ASK38711.1
                • pvL6
                		 30414 - 32011 (-) citrate synthase-like protein
                • Tailoring
                • Knock-out
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                • ASK38712.1
                • pvL5
                		 33721 - 34814 (+) dioxygenase
                • Tailoring
                • Knock-out
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                • ASK38713.1
                • pvL4
                		 36452 - 38034 (-) major facilitator superfamily transporter
                • Transport
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                • ASK38714.1
                • pvL3
                		 38429 - 39284 (+) ketosteroid isomerase-like protein
                • Tailoring
                • Knock-out
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                • ASK38715.1
                • pvL2
                		 39996 - 41525 (-) 2-methylcitrate dehydratase
                • Tailoring
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                • ASK38716.1
                • pvL1
                		 42010 - 42823 (+) hydrolase 341
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                  • ASK38717.1
                  • pvpks1
                  		 43533 - 51315 (+) polyketide synthase
                  • Scaffold biosynthesis
                  • Knock-out
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                  • ASK38718.1
                  • pvR1
                  		 51716 - 52424 (-) PEBP-like protein
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                    • ASK38719.1
                    • pvR2
                    		 55167 - 56534 (-) putative phosphotransferase
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                      Biosynthesis information

                      No biosynthesis information available for this record.

                      Annotation changelog

                      Entry version: 3

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-10-07
                      Update chemical activity to schema version 2.11
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 2

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2019-10-16
                      Migrated from v1.4
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2018-08-06
                      Submitted
                      • (ID: HXVGKRLKDXN3R6A25AQJSXQH)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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