BGC0001447: primycin biosynthetic gene cluster from Saccharomonospora azurea SZMC 14600
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Location: 70,636 - 183,487 nt. (total: 112,852 nt).
This entry is originally from NCBI GenBank AHBX01000216.1.

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core biosynthetic genes
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General
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Biosynthesis
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KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001447
Short description primycin biosynthetic gene cluster from Saccharomonospora azurea SZMC 14600
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AHBX01000216.1
70636 - 183316
via
Compounds
  • primycin
Species Saccharomonospora azurea SZMC 14600 [taxonomy]
References
Chemical products information
primycin Evidence:
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C55H103N3O17
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SZMC14600_23345
  • EHK80142.1
 70636 - 71199 (-) transcriptional regulator, TetR family protein
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    • SZMC14600_23350
    • EHK80143.1
    		 71286 - 71885 (+) dihydrofolate reductase
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      • SZMC14600_23355
      • EHK80144.1
      		 72076 - 72387 (+) hypothetical protein
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        • SZMC14600_23360
        • EHK80145.1
        		 72594 - 72992 (+) hypothetical protein
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          • SZMC14600_23365
          • EHK80146.1
          		 72996 - 73442 (-) hypothetical protein
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            • SZMC14600_23370
            • EHK80147.1
            		 73520 - 73981 (-) acetyltransferase
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              • SZMC14600_23375
              • EHK80148.1
              		 73986 - 74699 (-) hydrolase or acyltransferase of alpha/beta superfamily protein
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                • SZMC14600_23380
                • EHK80149.1
                		 74818 - 75120 (+) ArsR family transcriptional regulator
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                  • SZMC14600_23385
                  • EHK80150.1
                  		 75117 - 75506 (+) Glyoxalase/bleomycin resistance protein/dioxygenase
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                    • SZMC14600_23390
                    • EHK80151.1
                    		 75550 - 76314 (-) regulatory protein TetR
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                      • SZMC14600_23395
                      • EHK80152.1
                      		 76403 - 77563 (+) hypothetical protein
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                        • SZMC14600_23400
                        • EHK80153.1
                        		 77632 - 78066 (+) cytidine deaminase
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                          • SZMC14600_23405
                          • EHK80154.1
                          		 78427 - 80034 (+) acetyl/propionyl-CoA carboxylase, carboxyltransferase subunit
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                            • SZMC14600_23410
                            • EHK80155.1
                            		 80112 - 82436 (+) Penicillin amidase
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                              • SZMC14600_23415
                              • EHK80156.1
                              		 82439 - 83620 (-) hypothetical protein
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                                • SZMC14600_23420
                                • EHK80157.1
                                		 83620 - 83958 (-) hypothetical protein
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                                  • SZMC14600_23425
                                  • EHK80158.1
                                  		 84182 - 84970 (+) ABC transporter
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                                    • SZMC14600_23430
                                    • EHK80159.1
                                    		 84955 - 86508 (+) hypothetical protein
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                                      • SZMC14600_23435
                                      • EHK80160.1
                                      		 86593 - 87879 (-) cytochrome p450-like enzyme
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                                        • SZMC14600_23440
                                        • EHK80161.1
                                        		 88219 - 89724 (+) hypothetical protein
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                                          • SZMC14600_23445
                                          • EHK80162.1
                                          		 89862 - 90818 (+) hypothetical protein
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                                            • SZMC14600_23450
                                            • EHK80163.1
                                            		 90867 - 106292 (+) acyl transferase
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                                              • SZMC14600_23455
                                              • EHK80164.1
                                              		 106405 - 108696 (+) hypothetical protein
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                                                • SZMC14600_23460
                                                • EHK80165.1
                                                		 108947 - 114943 (+) beta-ketoacyl synthase
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                                                  • SZMC14600_23465
                                                  • EHK80166.1
                                                  		 114529 - 125637 (+) beta-ketoacyl synthase
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                                                    • SZMC14600_23470
                                                    • EHK80167.1
                                                    		 125661 - 143243 (+) modular polyketide synthase
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                                                      • SZMC14600_23475
                                                      • EHK80168.1
                                                      		 143450 - 145378 (+) acyl transferase
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                                                        • SZMC14600_23480
                                                        • EHK80169.1
                                                        		 145399 - 164463 (+) acyl transferase
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                                                          • SZMC14600_23485
                                                          • EHK80170.1
                                                          		 164460 - 169439 (+) acyl transferase
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                                                            • SZMC14600_23490
                                                            • EHK80171.1
                                                            		 169455 - 174941 (+) modular polyketide synthase
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                                                              • SZMC14600_23495
                                                              • EHK80172.1
                                                              		 175007 - 176134 (-) agmatinase
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                                                                • SZMC14600_23500
                                                                • EHK80173.1
                                                                		 176189 - 176392 (-) hypothetical protein
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                                                                  • SZMC14600_23505
                                                                  • EHK80174.1
                                                                  		 176582 - 177577 (+) ABC transporter ATP-binding protein
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                                                                    • SZMC14600_23510
                                                                    • EHK80175.1
                                                                    		 177574 - 178383 (+) ABC-transporter transmembrane protein
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                                                                      • SZMC14600_23515
                                                                      • EHK80176.1
                                                                      		 178441 - 179637 (+) two-component histidine kinase
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                                                                        • SZMC14600_23520
                                                                        • EHK80177.1
                                                                        		 179692 - 180330 (+) two-component system response regulator
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                                                                          • SZMC14600_23525
                                                                          • EHK80178.1
                                                                          		 180368 - 183316 (+) ATPase-like protein
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                                                                            Biosynthesis information

                                                                            No biosynthesis information available for this record.

                                                                            Annotation changelog

                                                                            Entry version: 3

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2024-07-27
                                                                            MIBiG v4 annotathon
                                                                            • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 2

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2019-10-16
                                                                            Migrated from v1.4
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            2019-10-16
                                                                            Updated reference publication(s) (MIBiG Annotathon)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            2019-10-16
                                                                            Updated compound(s) information (NPAtlas curation)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 1

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2018-08-06
                                                                            Submitted
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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