BGC0001455: antimycin biosynthetic gene cluster from Streptomyces argillaceus
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Location: 1 - 26,743 nt. (total: 26,743 nt).
This entry is originally from NCBI GenBank LT989885.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
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NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0001455
Short description antimycin biosynthetic gene cluster from Streptomyces argillaceus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: LT989885.1
Compounds
  • antimycin
Species Streptomyces argillaceus [taxonomy]
References
Chemical products information
antimycin
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C13H14O5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • antaA
 1 - 519 (-) RNA_polymerase,_sigma-24_subunit
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  • antaB
 580 - 1971 (-) Putative acyltransferase
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  • antaC
 2369 - 11245 (+) NRPS
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  • antaD
 11238 - 15053 (+) Type I PKS
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  • antaE
 15124 - 16353 (+) crotonyl-CoA_reductase
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  • antaF
 16782 - 18266 (-) putative Acyl-CoA ligase
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  • antaG
 18266 - 18526 (-) acyl_carrier_protein
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  • antaH
 18633 - 19985 (+) phenylacetate-CoA oxigenase
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  • antaI
 19982 - 20293 (+) 1,2-phenylacetate-CoA epoxidase
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  • antaJ
 20274 - 21134 (+) phenylacetate-CoA oxigenase
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  • antaK
 21131 - 21643 (+) phenylacetate-CoA oxigenase
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  • antaL
 21652 - 22839 (+) phenylacetate-CoA oxigenase
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  • antaM
 22918 - 23709 (+) 3-oxoacyl-ACP reductase
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  • antaN
 23801 - 24649 (+) tryptophan 2,3-dioxygenase
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  • antaO
 24639 - 25487 (+) lipase
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  • antaP
 25484 - 26743 (+) kynureninase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
antaC
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
antaF
Module ?
Specificity: anthanillic acid
Evidence for specificity:
  • Structure-based inference
  • Homology
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated reference publication(s) (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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Modifications to original record
  • antaA was added
  • antaB was added
  • antaC was added
  • antaD was added
  • antaE was added
  • antaF was added
  • antaG was added
  • antaH was added
  • antaI was added
  • antaJ was added
  • antaK was added
  • antaL was added
  • antaM was added
  • antaN was added
  • antaO was added
  • antaP was added