BGC0001569: dechlorocuracomycin biosynthetic gene cluster from Streptomyces noursei ATCC 11455
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Location: 2,863,457 - 2,909,713 nt. (total: 46,257 nt).
This entry is originally from NCBI GenBank CP011533.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001569
Short description dechlorocuracomycin biosynthetic gene cluster from Streptomyces noursei ATCC 11455
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: CP011533.1
Compounds
  • dechlorocuracomycin
Species Streptomyces noursei ATCC 11455 [taxonomy]
References
Chemical products information
dechlorocuracomycin
Copy SMILES
C37H57N9O8
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SNOUR_12590
  • ANZ15829.1
 2863457 - 2865154 (-) 2-isopropylmalate synthase
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  • SNOUR_12595
  • ANZ15830.1
 2865244 - 2866125 (-) amidinotransferase
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  • SNOUR_12600
  • ANZ15831.1
 2866175 - 2866720 (-) oxidase
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  • SNOUR_12605
  • ANZ15832.1
 2866717 - 2867973 (-) sodium/hydrogen exchanger
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  • SNOUR_12610
  • ANZ15833.1
 2868013 - 2869563 (-) tryptophan halogenase
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  • SNOUR_12615
  • ANZ15834.1
 2869733 - 2870248 (-) hypothetical protein
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  • SNOUR_12620
  • ANZ15835.1
 2870245 - 2871357 (-) putative branched-chain-amino-acid aminotransferase
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  • SNOUR_12625
  • ANZ15836.1
 2871402 - 2871788 (-) ketosteroid isomerase-like protein
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  • SNOUR_12630
  • ANZ15837.1
 2871778 - 2872794 (-) SyrP protein
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  • SNOUR_12635
  • ANZ15838.1
 2872817 - 2873029 (-) hypothetical protein
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  • SNOUR_12640
  • ANZ15839.1
 2873066 - 2880967 (-) peptide synthetase ScpsB
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  • SNOUR_12645
  • ANZ15840.1
 2881027 - 2895225 (-) non-ribosomal peptide synthase/amino acid adenylation enzyme
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  • SNOUR_12650
  • ANZ15841.1
 2895283 - 2896602 (-) penicillin-binding protein, beta-lactamase class C
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  • SNOUR_12655
  • ANZ15842.1
 2896793 - 2897209 (-) hypothetical protein
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  • SNOUR_12660
  • ANZ15843.1
 2897242 - 2899989 (-) ABC transporter permease
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  • SNOUR_12665
  • ANZ15844.1
 2899995 - 2900795 (-) putative ABC transporter ATP-binding protein
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  • SNOUR_12670
  • ANZ15845.1
 2901037 - 2902248 (+) integral membrane sensor signal transduction histidine kinase
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  • SNOUR_12675
  • ANZ15846.1
 2902236 - 2902907 (+) LuxR family two component transcriptional regulator
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  • SNOUR_12680
  • ANZ15847.1
 2903082 - 2903513 (-) hypothetical protein
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  • SNOUR_12685
  • ANZ15848.1
 2903554 - 2903763 (-) membrane protein
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  • SNOUR_12690
  • ANZ15849.1
 2904001 - 2905344 (+) arabinose efflux permease family protein
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  • SNOUR_12695
  • ANZ15850.1
 2905348 - 2906085 (+) Oleoyl-(acyl-carrier-protein) hydrolase
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  • SNOUR_12700
  • ANZ15851.1
 2906161 - 2906721 (-) ABC transporter
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  • SNOUR_12705
  • ANZ15852.1
 2907554 - 2909713 (-) RecQ family ATP-dependent DNA helicase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
SNOUR_12640
Module ?
Specificity: ornithine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: asparagine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
  • Homology
SNOUR_12645
Module ?
Specificity: tryptophan / 5-chlorotryptophan
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected publication
  • Added NRP substrate specificities
Detailed domain annotation
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