BGC0001578: duclauxin biosynthetic gene cluster from Talaromyces stipitatus ATCC 10500
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 750,099 - 796,895 nt. (total: 46,797 nt).
This entry is originally from NCBI GenBank EQ962653.1, but has been modified (see Modifications tab for details).

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
Modifications
General information about the BGC
MIBiG accession BGC0001578
Short description duclauxin biosynthetic gene cluster from Talaromyces stipitatus ATCC 10500
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
EQ962653.1
753988 - 785137
via
Compounds
  • duclauxin
Species Talaromyces stipitatus ATCC 10500 [taxonomy]
References
Chemical products information
duclauxin Evidence:
Copy SMILES
C29H22O11
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • TSTA_083230
  • EED21090.1
753988 - 754692 (-) aldo/keto reductase, putative
    copy AA seq
    copy Nt seq
    • TSTA_083240
    • EED21091.1
    755988 - 757625 (-) conserved hypothetical protein
      copy AA seq
      copy Nt seq
      • TSTA_083250
      • EED21092.1
      758846 - 761346 (+) C6 transcription factor, putative
        copy AA seq
        copy Nt seq
        • TSTA_083260
        • EED21093.1
        761567 - 762884 (-) cytochrome P450, putative
          copy AA seq
          copy Nt seq
          • TSTA_083270
          • EED21094.1
          763624 - 765077 (+) monooxygenase, putative
            copy AA seq
            copy Nt seq
            • TSTA_083280
            • EED21095.1
            765458 - 765917 (+) conserved hypothetical protein
              copy AA seq
              copy Nt seq
              • TSTA_083290
              • EED21096.1
              766407 - 767578 (+) conserved hypothetical protein
                copy AA seq
                copy Nt seq
                • TSTA_083290_rename1
                • EED21097.1
                766534 - 767578 (+) conserved hypothetical protein
                  copy AA seq
                  copy Nt seq
                  • TSTA_083300
                  • EED21098.1
                  767932 - 768925 (-) dienelactone hydrolase, putative
                    copy AA seq
                    copy Nt seq
                    • TSTA_083310
                    • EED21099.1
                    770099 - 776895 (-) polyketide synthase, putative
                      copy AA seq
                      copy Nt seq
                      • TSTA_083320
                      • EED21100.1
                      778426 - 779625 (+) Maleylacetate reductase, putative
                        copy AA seq
                        copy Nt seq
                        • TSTA_083330
                        • EED21101.1
                        780279 - 781789 (+) O-methyltransferase, putative
                          copy AA seq
                          copy Nt seq
                          • TSTA_083340
                          • EED21102.1
                          782267 - 783940 (-) cytochrome P450, putative
                            copy AA seq
                            copy Nt seq
                            • TSTA_083350
                            • EED21103.1
                            784425 - 785137 (+) conserved hypothetical protein
                              copy AA seq
                              copy Nt seq
                              Biosynthesis information

                              No biosynthesis information available for this record.

                              Annotation changelog

                              Entry version: 2

                              Date
                              Changes
                              Submitters
                              Reviewers
                              Migrated from v1.4
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              Updated compound(s) information (NPAtlas curation)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                              Entry version: 1

                              Date
                              Changes
                              Submitters
                              Reviewers
                              Submitted
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                              Similar known clusters from MIBiG 4.0
                              Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                              Detailed help and explanations are available here.

                              Click on reference genes to show details of similarities to genes within the current region.
                              Double click on a reference drawing to reverse the display of the genes.

                              Click on an accession to open that entry in the MIBiG database.


                              Location:

                              Identifier
                              Identity
                              Coverage
                              Detailed domain annotation
                              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                              A domain glossary is available here, and an explanation of the visualisation is available here.
                              Selected features only
                              Show module domains
                              Modifications to original record
                              • renamed CDS with name TSTA_083290 at join{[766533:766775](+), [766848:766922](+), [766982:767578](+)} to TSTA_083290_rename1 to avoid duplicates