BGC0001611: guangnanmycin biosynthetic gene cluster from Streptomyces sp. CB01883
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 72,893 nt. (total: 72,893 nt).
This entry is originally from NCBI GenBank MF925481.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001611
Short description guangnanmycin biosynthetic gene cluster from Streptomyces sp. CB01883
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type I)
Loci
MF925481.1
via
Compounds
  • guangnanmycin
Species Streptomyces sp. CB01883 [taxonomy]
References
Chemical products information
guangnanmycin Evidence: NMR [2], Mass spectrometry [2], [3]
Copy SMILES
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATY69549.1
 976 - 2301 (+) putative lanthionine synthetase
    copy AA seq
    copy Nt seq
    • ATY69550.1
    • gnmA
    		 2571 - 3008 (+) truncated hemoglobin
      copy AA seq
      copy Nt seq
      • ATY69551.1
      • gnmB
      		 3051 - 10070 (+) hybrid nonribosomal peptide synthetase/type I polyketide synthase
        copy AA seq
        copy Nt seq
        • ATY69552.1
        • gnmC
        		 10168 - 10926 (+) type II thioesterase
          copy AA seq
          copy Nt seq
          • ATY69553.1
          • gnmD
          		 10949 - 11716 (-) 4'-phosphopantetheinyl transferase
            copy AA seq
            copy Nt seq
            • ATY69554.1
            • gnmE
            		 11909 - 13141 (+) HMG-CoA synthase
              copy AA seq
              copy Nt seq
              • ATY69555.1
              • gnmF
              		 13149 - 13955 (+) enoyl-CoA hydratase
                copy AA seq
                copy Nt seq
                • ATY69556.1
                • gnmG
                		 14050 - 16539 (+) acyltransferase/oxidoreductase
                  copy AA seq
                  copy Nt seq
                  • ATY69557.1
                  • gnmH
                  		 16686 - 23213 (+) type I polyketide synthase
                    copy AA seq
                    copy Nt seq
                    • ATY69558.1
                    • gnmI
                    		 23260 - 24816 (+) antibiotic efflux protein
                      copy AA seq
                      copy Nt seq
                      • ATY69559.1
                      • gnmJ
                      		 24960 - 25859 (+) hypothetical protein
                        copy AA seq
                        copy Nt seq
                        • ATY69560.1
                        • gnmK
                        		 25856 - 28267 (+) acyltransferase/oxidoreductase
                          copy AA seq
                          copy Nt seq
                          • ATY69561.1
                          • gnmL
                          		 28312 - 29244 (+) hypothetical protein
                            copy AA seq
                            copy Nt seq
                            • ATY69562.1
                            • gnmM
                            		 29371 - 29736 (-) glyoxalase/bleomycin resistance protein
                              copy AA seq
                              copy Nt seq
                              • ATY69563.1
                              • gnmN
                              		 29851 - 30258 (-) hypothetical protein
                                copy AA seq
                                copy Nt seq
                                • ATY69564.1
                                • gnmO
                                		 30480 - 31196 (+) N-acetylglucosaminyl deacetylase
                                  copy AA seq
                                  copy Nt seq
                                  • ATY69565.1
                                  • gnmP
                                  		 31255 - 32001 (-) Methyltransferase
                                  • Methylation
                                  copy AA seq
                                  copy Nt seq
                                  • ATY69566.1
                                  • gnmQ
                                  		 31998 - 34106 (-) putative alpha/beta hydrolase
                                    copy AA seq
                                    copy Nt seq
                                    • ATY69567.1
                                    • gnmR
                                    		 34450 - 34704 (+) peptidyl carrier protein
                                      copy AA seq
                                      copy Nt seq
                                      • ATY69568.1
                                      • gnmS
                                      		 34701 - 36329 (+) adenylation protein
                                        copy AA seq
                                        copy Nt seq
                                        • ATY69569.1
                                        • gnmT
                                        		 36326 - 58594 (+) type I polyketide synthase
                                          copy AA seq
                                          copy Nt seq
                                          • ATY69570.1
                                          • gnmU
                                          		 58591 - 59838 (+) HMG-CoA synthase
                                            copy AA seq
                                            copy Nt seq
                                            • ATY69571.1
                                            • gnmV
                                            		 59858 - 60133 (+) acyl carrier protein
                                              copy AA seq
                                              copy Nt seq
                                              • ATY69572.1
                                              • gnmW
                                              		 60157 - 61428 (+) beta-ketoacyl-ACP synthase
                                                copy AA seq
                                                copy Nt seq
                                                • ATY69573.1
                                                • gnmX
                                                		 61544 - 62797 (+) cytochrome P450 oxygenase
                                                  copy AA seq
                                                  copy Nt seq
                                                  • ATY69574.1
                                                  • gnmY
                                                  		 62854 - 64155 (+) aminotransferase
                                                    copy AA seq
                                                    copy Nt seq
                                                    • ATY69575.1
                                                    • gnmZ
                                                    		 64119 - 64808 (-) Crp/Fnr family transcriptional regulator
                                                      copy AA seq
                                                      copy Nt seq
                                                      • ATY69576.1
                                                      		 65382 - 67667 (+) AfsR-like regulatory protein
                                                        copy AA seq
                                                        copy Nt seq
                                                        Biosynthesis information

                                                        No biosynthesis information available for this record.

                                                        Annotation changelog

                                                        Entry version: 4

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2024-05-14
                                                        MIBiG v4 annotathon
                                                        • (ID: Z4WHVO6K4QR4NSPFS3BTTXEO)
                                                        • (ID: YO3TP6VWB5CBNPZKNYNQSKUW)
                                                        • (ID: P75FRHHCFPTCPYSP65VDVPHW)
                                                        • (ID: I3D2K5SU7JJDS2LEEQM3W3SO)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 3

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2022-09-15
                                                        Added NRP substrate specificities
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 2

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2019-10-16
                                                        Migrated from v1.4
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 1

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2018-08-06
                                                        Submitted
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        Similar known clusters from MIBiG 4.0
                                                        Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                        Detailed help and explanations are available here.

                                                        Click on reference genes to show details of similarities to genes within the current region.
                                                        Double click on a reference drawing to reverse the display of the genes.

                                                        Click on an accession to open that entry in the MIBiG database.


                                                        Location:

                                                        Identifier
                                                        Identity
                                                        Coverage
                                                        Detailed domain annotation
                                                        Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                        A domain glossary is available here, and an explanation of the visualisation is available here.
                                                        Selected features only
                                                        Show module domains