BGC0001611: guangnanmycin biosynthetic gene cluster from Streptomyces sp. CB01883
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Location: 1 - 72,893 nt. (total: 72,893 nt).
This entry is originally from NCBI GenBank MF925481.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001611
Short description guangnanmycin biosynthetic gene cluster from Streptomyces sp. CB01883
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: MF925481.1
Compounds
  • guangnanmycin
Species Streptomyces sp. CB01883 [taxonomy]
References
Chemical products information
guangnanmycin
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATY69549.1
 976 - 2301 (+) putative lanthionine synthetase
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  • ATY69550.1
  • gnmA
 2571 - 3008 (+) truncated hemoglobin
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  • ATY69551.1
  • gnmB
 3051 - 10070 (+) hybrid nonribosomal peptide synthetase/type I polyketide synthase
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  • ATY69552.1
  • gnmC
 10168 - 10926 (+) type II thioesterase
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  • ATY69553.1
  • gnmD
 10949 - 11716 (-) 4'-phosphopantetheinyl transferase
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  • ATY69554.1
  • gnmE
 11909 - 13141 (+) HMG-CoA synthase
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  • ATY69555.1
  • gnmF
 13149 - 13955 (+) enoyl-CoA hydratase
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  • ATY69556.1
  • gnmG
 14050 - 16539 (+) acyltransferase/oxidoreductase
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  • ATY69557.1
  • gnmH
 16686 - 23213 (+) type I polyketide synthase
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  • ATY69558.1
  • gnmI
 23260 - 24816 (+) antibiotic efflux protein
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  • ATY69559.1
  • gnmJ
 24960 - 25859 (+) hypothetical protein
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  • ATY69560.1
  • gnmK
 25856 - 28267 (+) acyltransferase/oxidoreductase
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  • ATY69561.1
  • gnmL
 28312 - 29244 (+) hypothetical protein
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  • ATY69562.1
  • gnmM
 29371 - 29736 (-) glyoxalase/bleomycin resistance protein
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  • ATY69563.1
  • gnmN
 29851 - 30258 (-) hypothetical protein
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  • ATY69564.1
  • gnmO
 30480 - 31196 (+) N-acetylglucosaminyl deacetylase
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  • ATY69565.1
  • gnmP
 31255 - 32001 (-) methyltransferase
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  • ATY69566.1
  • gnmQ
 31998 - 34106 (-) putative alpha/beta hydrolase
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  • ATY69567.1
  • gnmR
 34450 - 34704 (+) peptidyl carrier protein
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  • ATY69568.1
  • gnmS
 34701 - 36329 (+) adenylation protein
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  • ATY69569.1
  • gnmT
 36326 - 58594 (+) type I polyketide synthase
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  • ATY69570.1
  • gnmU
 58591 - 59838 (+) HMG-CoA synthase
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  • ATY69571.1
  • gnmV
 59858 - 60133 (+) acyl carrier protein
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  • ATY69572.1
  • gnmW
 60157 - 61428 (+) beta-ketoacyl-ACP synthase
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  • ATY69573.1
  • gnmX
 61544 - 62797 (+) cytochrome P450 oxygenase
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  • ATY69574.1
  • gnmY
 62854 - 64155 (+) aminotransferase
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  • ATY69575.1
  • gnmZ
 64119 - 64808 (-) Crp/Fnr family transcriptional regulator
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  • ATY69576.1
 65382 - 67667 (+) AfsR-like regulatory protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
gnmB
Module ?
Specificity: D-alanine
Evidence for specificity:
  • Structure-based inference
  • Heterologous expression
  • Sequence-based prediction
gnmS
Module ?
Specificity: 1-aminocyclopropane-1-carboxylic acid
Evidence for specificity:
  • Structure-based inference
  • Heterologous expression
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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