BGC0001762: rubrolone A biosynthetic gene cluster from Streptomyces sp. KIB-H033
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 36,216 nt. (total: 36,216 nt).
This entry is originally from NCBI GenBank KX218108.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001762
Short description rubrolone A biosynthetic gene cluster from Streptomyces sp. KIB-H033
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Alkaloid
Loci NCBI GenBank: KX218108.1
Compounds
  • rubrolone A
  • rubrolone B
Species Streptomyces sp. KIB-H033 [taxonomy]
References
Chemical products information
rubrolone A
(no structure information available)
rubrolone B
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AOZ61185.1
1 - 1356 (+) amidohydrolase
copy AA seq
copy Nt seq
  • AOZ61186.1
1411 - 1920 (-) marR family transcriptional regulator
copy AA seq
copy Nt seq
  • AOZ61187.1
2048 - 3112 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AOZ61188.1
3203 - 4120 (-) transposase
copy AA seq
copy Nt seq
  • AOZ61189.1
4159 - 4557 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AOZ61190.1
4617 - 5012 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AOZ61191.1
5013 - 5951 (-) zinc-containing alcohol dehydrogenase
copy AA seq
copy Nt seq
  • AOZ61192.1
  • rubS1
6260 - 7738 (+) FAD-linked oxidoreductase
copy AA seq
copy Nt seq
  • AOZ61193.1
  • rubN1
7735 - 8142 (+) hypothetical protein
copy AA seq
copy Nt seq
  • AOZ61194.1
  • rubS2
8255 - 8869 (+) dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
copy AA seq
copy Nt seq
  • AOZ61195.1
  • rubS3
9005 - 9937 (-) dTDP-glucose-4-ketoreductase
copy AA seq
copy Nt seq
  • AOZ61196.1
  • rubS4
9934 - 10965 (-) dTDP-glucose 4,6 dehydratase
copy AA seq
copy Nt seq
  • AOZ61197.1
  • rubS5
10982 - 11851 (-) Glucose-1-phosphate thymidylyltransferase
copy AA seq
copy Nt seq
  • AOZ61198.1
  • rubS6
11873 - 12709 (-) NAD dependent epimerase/dehydratase
copy AA seq
copy Nt seq
  • AOZ61199.1
  • rubS7
12820 - 13974 (-) Glycosyltransferase
copy AA seq
copy Nt seq
  • AOZ61200.1
  • rubR
14184 - 15221 (-) SARP family transcriptional regulator
copy AA seq
copy Nt seq
  • AOZ61201.1
  • rubN2
15281 - 15628 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AOZ61202.1
  • rubA
16270 - 17205 (+) F420-dependent oxidoreductase
copy AA seq
copy Nt seq
  • AOZ61203.1
  • rubB
17783 - 19339 (+) oxygenase
copy AA seq
copy Nt seq
  • AOZ61204.1
  • rubC
19336 - 20505 (+) naphthocyclinone hydroxylase
copy AA seq
copy Nt seq
  • AOZ61205.1
  • rubE1
20878 - 21837 (-) ketoacylsynthase III
copy AA seq
copy Nt seq
  • AOZ61206.1
  • rubE2
22119 - 22394 (+) acyl carrier protein
copy AA seq
copy Nt seq
  • AOZ61207.1
  • rubE3
22549 - 23469 (+) acyl transferase
copy AA seq
copy Nt seq
  • AOZ61208.1
  • rubE4
23539 - 23793 (+) acyl carrier protein
copy AA seq
copy Nt seq
  • AOZ61209.1
  • rubE5
24233 - 24727 (+) bifunctional cyclase/dehydratase
copy AA seq
copy Nt seq
  • AOZ61210.1
  • rubE6
24727 - 25482 (+) cyclase
copy AA seq
copy Nt seq
  • AOZ61211.1
  • rubE7
25479 - 26099 (+) NADH dehydrogenase/NADPH nitroreductase
copy AA seq
copy Nt seq
  • AOZ61212.1
  • rubE8
26249 - 27478 (+) beta-ketoacylsynthase I
copy AA seq
copy Nt seq
  • AOZ61213.1
  • rubE9
27508 - 28710 (+) chain length factor
copy AA seq
copy Nt seq
  • AOZ61214.1
28805 - 29917 (-) Isopentenyl-diphosphate delta-isomerase
copy AA seq
copy Nt seq
  • AOZ61216.1
30185 - 30424 (-) hypothetical protein
copy AA seq
copy Nt seq
  • AOZ61215.1
30410 - 31942 (+) methylmalonyl-CoA decarboxylase subunit alpha
copy AA seq
copy Nt seq
  • AOZ61217.1
32690 - 33895 (+) 3-oxoadipate enol-lactonase
copy AA seq
copy Nt seq
  • AOZ61218.1
34034 - 34678 (+) metallo-beta-lactamase domain protein
copy AA seq
copy Nt seq
  • AOZ61219.1
34772 - 35551 (+) exodeoxyribonuclease III
copy AA seq
copy Nt seq
  • AOZ61220.1
35770 - 36216 (+) hypothetical protein
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.