BGC0001785: streptovaricin biosynthetic gene cluster from Streptomyces spectabilis
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 95,304 nt. (total: 95,304 nt).
This entry is originally from NCBI GenBank KY593296.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001785
Short description streptovaricin biosynthetic gene cluster from Streptomyces spectabilis
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: KY593296.1
Compounds
  • streptovaricin
Species Streptomyces spectabilis [taxonomy]
References
Chemical products information
streptovaricin
Copy SMILES
C40H51N1O14
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ASZ00129.1
  • stvA1
 348 - 707 (+) acetyltransferase
copy AA seq
copy Nt seq
  • ASZ00130.1
 740 - 1354 (+) arylsulfatase
copy AA seq
copy Nt seq
  • ASZ00131.1
 1380 - 1703 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ASZ00132.1
 1722 - 3161 (-) 6-phosphogluconate dehydrogenase
copy AA seq
copy Nt seq
  • ASZ00133.1
 3335 - 4306 (+) acetyl xylan esterase
copy AA seq
copy Nt seq
  • ASZ00134.1
 4428 - 5765 (+) peptidase
copy AA seq
copy Nt seq
  • ASZ00135.1
 5854 - 7074 (-) membrane protein
copy AA seq
copy Nt seq
  • ASZ00136.1
 7347 - 8063 (+) ferric iron reductase
copy AA seq
copy Nt seq
  • ASZ00137.1
 8239 - 9288 (+) glycosyl transferase
copy AA seq
copy Nt seq
  • ASZ00138.1
 9379 - 10599 (+) glucose-1-phosphate adenylyltransferase
copy AA seq
copy Nt seq
  • ASZ00139.1
  • stvO1
 10846 - 11814 (+) NADH-dependent dehydrogenase
copy AA seq
copy Nt seq
  • ASZ00140.1
  • stvO2
 11823 - 12806 (+) oxidoreductase
copy AA seq
copy Nt seq
  • ASZ00141.1
  • stvO3
 12889 - 13452 (+) NADPH-dependent reductase
copy AA seq
copy Nt seq
  • ASZ00142.1
  • stvP1
 13481 - 14773 (+) cytochrome P450
copy AA seq
copy Nt seq
  • ASZ00143.1
  • stvM1
 15159 - 15767 (+) type 11 methyltransferase
copy AA seq
copy Nt seq
  • ASZ00144.1
  • stvP2
 15800 - 17005 (+) cytochrome P450
copy AA seq
copy Nt seq
  • ASZ00145.1
  • stvA2
 17106 - 18275 (-) acyltransferase PapA5
copy AA seq
copy Nt seq
  • ASZ00146.1
  • stvP3
 18765 - 19958 (+) cytochrome P450
copy AA seq
copy Nt seq
  • ASZ00147.1
  • stvA
 20415 - 37088 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ASZ00148.1
  • stvB
 37120 - 47883 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ASZ00149.1
  • stvC
 48086 - 58798 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ASZ00150.1
  • stvD
 58958 - 64522 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ASZ00151.1
  • stvE
 64592 - 75304 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ASZ00152.1
  • stvF
 75408 - 76202 (+) amide synthase
copy AA seq
copy Nt seq
  • ASZ00153.1
  • stvG
 76251 - 77324 (+) 3-dehydroquinate synthase
copy AA seq
copy Nt seq
  • ASZ00154.1
  • stvH
 77495 - 78649 (+) NAHP synthase
copy AA seq
copy Nt seq
  • ASZ00155.1
  • stvI
 78657 - 79469 (+) shikimate dehydrogenase
copy AA seq
copy Nt seq
  • ASZ00156.1
  • stvK
 79685 - 80845 (+) AHBA synthase
copy AA seq
copy Nt seq
  • ASZ00157.1
  • stvL
 81127 - 81942 (+) oxidoreductase
copy AA seq
copy Nt seq
  • ASZ00158.1
  • stvM
 82095 - 82679 (+) phosphoglycolate phosphatase
copy AA seq
copy Nt seq
  • ASZ00159.1
  • stvN
 82699 - 83652 (+) AHBA kinase
copy AA seq
copy Nt seq
  • ASZ00160.1
  • stvP4
 83977 - 85221 (+) cytochrome P450
copy AA seq
copy Nt seq
  • ASZ00161.1
  • stvO4
 85273 - 86934 (-) 3-(3-hydroxyphenyl)propionate hydroxylase
copy AA seq
copy Nt seq
  • ASZ00162.1
  • stvP5
 87228 - 88481 (+) cytochrome P450
copy AA seq
copy Nt seq
  • ASZ00163.1
  • stvM2
 88593 - 89660 (-) SAM-dependent methyltransferase
copy AA seq
copy Nt seq
  • ASZ00164.1
  • stvM3
 89737 - 90540 (-) type 11 methyltransferase
copy AA seq
copy Nt seq
  • ASZ00165.1
 90785 - 90982 (-) ferredoxin
copy AA seq
copy Nt seq
  • ASZ00166.1
  • stvR1
 91314 - 92612 (-) LuxR family transcriptional regulator
copy AA seq
copy Nt seq
  • ASZ00167.1
 92941 - 93300 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ASZ00168.1
  • stvR2
 93785 - 94414 (+) putative OmpR family two component response regulator
copy AA seq
copy Nt seq
  • ASZ00169.1
  • stvJ
 94424 - 94975 (-) aminodehydroquinate dehydratase
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.