BGC0001850: diazaquinomycin A biosynthetic gene cluster from Streptomyces sp. F001
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 257,859 - 281,361 nt. (total: 23,503 nt).
This entry is originally from NCBI GenBank QZWF01000007.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001850
Short description diazaquinomycin A biosynthetic gene cluster from Streptomyces sp. F001
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "additional key publication:Braesel, J., Lee, J.-H., Arnould, B., Murphy, B.T., Eustaquio, A.S. (2019) Diazaquinomycin biosynthetic gene clusters from marine and freshwater actinomycetes. J. Nat. Prod., in revisionBraesel, J.; Clark, C. M., Kunstman, K. J., Green, S. J., Maienschein-Cline, M., Murphy, B. T., Eustáquio, A. S. (2019) Genome sequence of marine-derived Streptomyces sp. F001, a producer of akashin A and diazaquinomycins. submitted to Microbiology Resource Announcement"
Biosynthetic class(es)
  • Other (Shikimate-derived)
Loci NCBI GenBank: QZWF01000007.1
Compounds
  • diazaquinomycin A
  • diazaquinomycin E
  • diazaquinomycin F
  • diazaquinomycin G
Species Streptomyces sp. F001 [taxonomy]
References
Chemical products information
diazaquinomycin A [synonyms: om-704 a, brn 4578367, diazaquinomicin a, nsc-626554, ls-134243]
Copy SMILES
C20H22N2O4
Chemical database entries
PubCHEM
diazaquinomycin E
Copy SMILES
C22H26N2O4
Chemical database entries
PubCHEM
diazaquinomycin F
Copy SMILES
C21H24N2O4
diazaquinomycin G
Copy SMILES
C21H24N2O4
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • StrepF001_25885
  • RZB16697.1
 258927 - 259739 (-) acetyltransferase
copy AA seq
copy Nt seq
  • StrepF001_25890
  • RZB16698.1
 259770 - 260582 (-) acetyltransferase
copy AA seq
copy Nt seq
  • StrepF001_25895
  • RZB16699.1
 260589 - 261650 (-) amidohydrolase
copy AA seq
copy Nt seq
  • StrepF001_25900
  • RZB16700.1
 261660 - 262064 (-) nuclear transport factor 2 family protein
copy AA seq
copy Nt seq
  • StrepF001_25905
  • RZB16701.1
 262283 - 262963 (+) NAD(P)H dehydrogenase
copy AA seq
copy Nt seq
  • StrepF001_25910
  • RZB16702.1
 263163 - 263867 (+) SDR family oxidoreductase
copy AA seq
copy Nt seq
  • StrepF001_25915
  • RZB16703.1
 263936 - 264940 (-) ketoacyl-ACP synthase III
copy AA seq
copy Nt seq
  • StrepF001_25920
  • RZB16704.1
 265176 - 265937 (-) TetR family transcriptional regulator
copy AA seq
copy Nt seq
  • StrepF001_25925
  • RZB16705.1
 266116 - 266763 (+) NAD-dependent epimerase/dehydratase family protein
copy AA seq
copy Nt seq
  • StrepF001_25930
  • RZB16796.1
 267417 - 268547 (+) transposase
copy AA seq
copy Nt seq
  • StrepF001_25935
  • RZB16706.1
 268436 - 270079 (+) phospho-2-dehydro-3-deoxyheptonate aldolase
copy AA seq
copy Nt seq
  • StrepF001_25940
  • RZB16707.1
 270145 - 270915 (+) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
copy AA seq
copy Nt seq
  • StrepF001_25945
  • RZB16708.1
 270948 - 271613 (+) isochorismatase family protein
copy AA seq
copy Nt seq
  • StrepF001_25950
  • RZB16709.1
 271610 - 273475 (+) phenazine-specific anthranilate synthase component I
copy AA seq
copy Nt seq
  • StrepF001_25955
  • RZB16710.1
  • pcaB
 273538 - 274920 (-) 3-carboxy-cis,cis-muconate cycloisomerase
copy AA seq
copy Nt seq
  • StrepF001_25960
  • RZB16711.1
 274917 - 276866 (-) FAD-binding protein
copy AA seq
copy Nt seq
  • StrepF001_25965
  • RZB16712.1
 276863 - 278053 (-) FAD-binding protein
copy AA seq
copy Nt seq
  • StrepF001_25970
  • RZB16713.1
 278062 - 279633 (-) acyl-CoA synthetase
copy AA seq
copy Nt seq
  • StrepF001_25975
  • RZB16714.1
 279712 - 280290 (-) SRPBCC family protein
copy AA seq
copy Nt seq
  • StrepF001_25980
  • RZB16715.1
 280365 - 281351 (-) NADPH:quinone reductase
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: GMXWAML5TKYYBXKHYBMH2DDT, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Cleaned up synonym list
  • Fetch compound properties from PubChem
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.