BGC0001854: tricholignan A biosynthetic gene cluster from Trichoderma harzianum
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Location: 22,313 - 56,389 nt. (total: 34,077 nt).
This entry is originally from NCBI GenBank JOKZ01000220.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001854
Short description tricholignan A biosynthetic gene cluster from Trichoderma harzianum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Iterative type I)
Loci
JOKZ01000220.1
22313 - 56389
via Gene expression correlated with compound production
Compounds
  • tricholignan A
Species Trichoderma harzianum [taxonomy]
References
Chemical products information
tricholignan A Evidence: NMR
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • THAR02_06934
  • KKP00962.1
 22314 - 27104 (+) hypothetical protein
  • Transport
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  • THAR02_06935
  • KKP00963.1
 27636 - 35087 (-) fatty acid synthase S-acetyltransferase
  • Scaffold biosynthesis
  • Activity assay
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  • THAR02_06936
  • KKP00964.1
 35624 - 36801 (+) hypothetical protein
  • Scaffold biosynthesis
  • Activity assay
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  • THAR02_06937
  • KKP00965.1
 37809 - 39569 (+) FAD dependent oxidoreductase
  • Tailoring
  • Activity assay
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  • THAR02_06938
  • KKP00966.1
 40313 - 45618 (+) RADS2 nonreducing polyketide synthase
  • Scaffold biosynthesis
  • Activity assay
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  • THAR02_06939
  • KKP00967.1
 48945 - 50038 (-) hypothetical protein
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    • THAR02_06940
    • KKP00968.1
    		 50520 - 51461 (+) hypothetical protein
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      • THAR02_06941
      • KKP00969.1
      		 52440 - 53897 (-) methyltransferase domain-containing protein
      • Scaffold biosynthesis
      • Activity assay
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      • THAR02_06942
      • KKP00970.1
      		 54904 - 56388 (+) hypothetical protein
      • Tailoring
      • Activity assay
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      Biosynthesis information
      Annotation changelog

      Entry version: 3

      Date
      Changes
      Submitters
      Reviewers
      2022-10-07
      Update chemical activity to schema version 2.11
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

      Entry version: 2

      Date
      Changes
      Submitters
      Reviewers
      2022-09-15
      Remove negative molecular mass
      • (ID: 3UOU7PODQJXIM6BEPUHHRRA5)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      2022-09-15
      Extended locus to include KKP00962.1 and removed the gene as an additional 'extra'
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

      Entry version: 1

      Date
      Changes
      Submitters
      Reviewers
      2019-10-16
      Submitted
      • (ID: AK5NYVRLOZHRMH3OHIPC6VPO)
      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
      Detailed domain annotation
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