BGC0001884: aranazole A biosynthetic gene cluster from Fischerella sp. PCC 9339
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Location: 1 - 41,956 nt. (total: 41,956 nt).
This entry is originally from NCBI GenBank BK010684.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001884
Short description aranazole A biosynthetic gene cluster from Fischerella sp. PCC 9339
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
BK010684.1
via
Compounds
  • aranazole A
  • aranazole B
  • aranazole C
  • aranazole D
Species Fischerella sp. PCC 9339 [taxonomy]
References
Chemical products information
aranazole A Evidence:
(no structure information available)
aranazole B Evidence:
(no structure information available)
aranazole C Evidence:
(no structure information available)
aranazole D Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • DAB41903.1
  • arzA
 1 - 1371 (+) ArzA - cytochrome P450
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    • DAB41904.1
    • arzB
    		 2003 - 3328 (+) ArzB - aKG/Fe(II) oxygenase
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      • DAB41905.1
      • arzC
      		 3521 - 4729 (+) ArzC - aKG/Fe(II) halogenase
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        • DAB41906.1
        • arzD
        		 4821 - 6158 (+) ArzD - aKG/Fe(II) halogenase
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          • DAB41907.1
          • arzE
          		 6482 - 7402 (+) ArzE - Rieske protein
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            • DAB41908.1
            • arzF
            		 7580 - 8902 (+) ArzF - aKG/Fe(II) halogenase
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              • DAB41909.1
              • arzG
              		 8994 - 10289 (+) ArzG - aKG/Fe(II) halogenase
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                • DAB41910.1
                • arzH
                		 10378 - 11781 (+) ArzH - cytochrome P450
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                  • DAB41911.1
                  • arzI
                  		 12200 - 13456 (+) ArzI - aKG/Fe(II) halogenase
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                    • DAB41912.1
                    • arzJ
                    		 13544 - 14851 (+) ArzJ - aKG/Fe(II) halogenase
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                      • DAB41913.1
                      • arzK
                      		 15005 - 15799 (+) ArzK - O-methyltransferase
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                        • DAB41914.1
                        • arzL
                        		 16731 - 19034 (+) ArzL - PKS (FAAL, ACP)
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                          • DAB41915.1
                          • arzM
                          		 18967 - 26811 (+) ArzM - PKS (KS, AT, DH, MT, ER, KR, ACP)
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                            • DAB41916.1
                            • arzN
                            		 26801 - 32554 (+) ArzN - PKS (KS, AT, OMT, KR, ACP)
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                              • DAB41917.1
                              • arzO
                              		 32551 - 36813 (+) ArzO - NRPS (Cy, A, Ox, PCP)
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                                • DAB41918.1
                                • arzP
                                		 36806 - 41956 (+) ArzP - PKS (KS, AT, OMT, ACP, TE)
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                                  Biosynthesis information

                                  Biosynthetic modules

                                  Name
                                  Unk01
                                  Type
                                  nrps-type1
                                  Genes
                                  arzO
                                  Substrates
                                  cysteine (evidence: Sequence-based prediction, Structure-based inference)
                                  Integrated Monomers
                                  Domains
                                  adenylation
                                  Annotation changelog

                                  Entry version: 2

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2022-09-15
                                  Added NRP substrate specificities
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                  Entry version: 1

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2019-10-16
                                  Submitted
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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