BGC0001885: oxazolepoxidomycin A biosynthetic gene cluster from Streptomyces sp. NRRL F-4335
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Location: 1 - 83,425 nt. (total: 83,425 nt).
This entry is originally from NCBI GenBank BK010686.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001885
Short description oxazolepoxidomycin A biosynthetic gene cluster from Streptomyces sp. NRRL F-4335
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
BK010686.1
via
Compounds
  • oxazolepoxidomycin A
Species Streptomyces sp. NRRL F-4335 [taxonomy]
References
Chemical products information
oxazolepoxidomycin A Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • DAC76727.1
  • ozeO
 1 - 846 (+) methyltransferase
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    • DAC76728.1
    • ozeA
    		 14314 - 17643 (+) type I polyketide synthase
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      • DAC76729.1
      • ozeB
      		 17586 - 21173 (+) type I polyketide synthase
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        • DAC76730.1
        • ozeC
        		 21121 - 31488 (+) type I polyketide synthase
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          • DAC76731.1
          • ozeD
          		 31485 - 35111 (+) methionyl-tRNA formyltransferase
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            • DAC76732.1
            • ozeE
            		 35174 - 36307 (+) oxazole cyclization protein
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              • DAC76733.1
              • ozeF
              		 36324 - 39059 (+) type I polyketide synthase
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                • DAC76734.1
                • ozeG
                		 39089 - 64123 (+) type I polyketide synthase/non-ribosomal peptide synthetase
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                  • DAC76735.1
                  • ozeH
                  		 64127 - 69145 (+) type I polyketide synthase
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                    • DAC76736.1
                    • ozeI
                    		 69191 - 75313 (+) non-ribosomal peptide synthetase
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                      • DAC76737.1
                      • ozeJ
                      		 75310 - 78732 (+) malonyl CoA-acyl carrier protein transacylase
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                        • DAC76738.1
                        • ozeK
                        		 78801 - 80183 (-) cytochrome P450
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                          • DAC76739.1
                          • ozeL
                          		 80216 - 81595 (-) cytochrome P450
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                            • DAC76740.1
                            • ozeM
                            		 81777 - 82691 (+) crotonyl-CoA reductase/alcohol dehydrogenase
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                              • DAC76741.1
                              • ozeN
                              		 82688 - 83425 (+) 4'-phosphopantetheinyl transferase
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                                Biosynthesis information

                                Biosynthetic modules

                                Name
                                Unk01
                                Type
                                nrps-type1
                                Genes
                                ozeD
                                Substrates
                                glycine (evidence: Structure-based inference, Sequence-based prediction)
                                Integrated Monomers
                                Domains
                                adenylation
                                Name
                                Unk02
                                Type
                                nrps-type1
                                Genes
                                ozeG
                                Substrates
                                glycine (evidence: Structure-based inference, Sequence-based prediction)
                                Integrated Monomers
                                Domains
                                adenylation
                                Name
                                Unk03
                                Type
                                nrps-type1
                                Genes
                                ozeI
                                Substrates
                                serine (evidence: Structure-based inference, Sequence-based prediction)
                                Integrated Monomers
                                Domains
                                adenylation
                                Annotation changelog

                                Entry version: 2

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-09-15
                                Fixed biosynthetic classes
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2022-09-15
                                Added NRP substrate specificities
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 1

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2019-10-16
                                Submitted
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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                                Detailed domain annotation
                                Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
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