BGC0001968: cadaside A biosynthetic gene cluster from uncultured bacterium
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Location: 11,462 - 81,357 nt. (total: 69,896 nt).
This entry is originally from NCBI GenBank MK060022.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001968
Short description cadaside A biosynthetic gene cluster from uncultured bacterium
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: MK060022.1
Compounds
  • cadaside A
  • cadaside B
Species uncultured bacterium [taxonomy]
References
Chemical products information
cadaside A
(no structure information available)
cadaside B
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QBC75013.1
  • cdeA
 14462 - 15688 (+) cytochrome P450
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  • QBC75014.1
  • cdeB
 15709 - 16515 (+) alpha/beta hydrolase
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  • QBC75015.1
  • cdeC
 16538 - 17386 (-) ABC transporter permease
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  • QBC75016.1
  • cdeD
 17416 - 18354 (-) daunorubicin/doxorubicin resistance ABC transporter
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  • QBC75017.1
  • cdeE
 18851 - 20602 (+) acyl-CoA synthase
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  • QBC75018.1
  • cdeF
 20679 - 22382 (+) acyl-CoA dehydrogenase
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  • QBC75019.1
  • cdeG
 22379 - 24115 (+) acyl-CoA dehydrogenase
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  • QBC75020.1
  • cdeH
 24203 - 24493 (+) acyl carrier protein
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  • QBC75021.1
  • cdeI
 24502 - 46215 (+) non-ribosomal peptide synthetase
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  • QBC75022.1
  • cdeJ
 46224 - 63350 (+) non-ribosomal peptide synthetase
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  • QBC75023.1
  • cdeK
 63347 - 71701 (+) non-ribosomal peptide synthetase
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  • QBC75024.1
  • cdeL
 71725 - 71946 (+) MbtH-like protein
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  • QBC75025.1
  • cdeM
 72125 - 72856 (+) phosphatase PAP2 family protein
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  • QBC75026.1
  • cdeN
 72898 - 73839 (+) alpha-ketoglutarate-dependent taurine dioxygenase
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  • QBC75027.1
  • cdeO
 73894 - 74955 (-) branched-chain amino acid aminotransferase
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  • QBC75028.1
  • cdeP
 74974 - 75360 (-) ketosteroid isomerase
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  • QBC75029.1
  • cdeQ
 75544 - 76239 (+) phosphatase PAP2 family protein
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  • QBC75030.1
  • cdeR
 76625 - 78079 (+) sensor histidine kinase
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  • QBC75031.1
  • cdeS
 78172 - 78810 (+) DNA-binding response regulator
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  • QBC75032.1
  • cdeT
 79086 - 80216 (+) succinate-semialdehyde dehydrogenase
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  • QBC75033.1
  • cdeU
 80632 - 81357 (-) SDR family NAD(P)-dependent oxidoreductase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
cdeI
Module ?
Specificity: 3R-aminoisobutyric acid
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glutamic acid
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
cdeJ
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: proline
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glutamic acid
Evidence for specificity:
  • Structure-based inference
cdeK
Module ?
Specificity: glutamic acid
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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