BGC0002000: setomimycin biosynthetic gene cluster from Streptomyces aurantiacus JA 4570
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Location: 2,057 - 14,558 nt. (total: 12,502 nt).
This entry is originally from NCBI GenBank NZ_AOPZ01000074.1.

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core biosynthetic genes
additional biosynthetic genes
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resistance
TTA codons
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General
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General information about the BGC
MIBiG accession BGC0002000
Short description setomimycin biosynthetic gene cluster from Streptomyces aurantiacus JA 4570
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: NZ_AOPZ01000074.1
Compounds
  • setomimycin
Species Streptomyces aurantiacus JA 4570 [taxonomy]
References
Chemical products information
setomimycin
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C34H28O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • STRAU_RS10340
  • WP_016640227.1
2057 - 3571 (+) DHA2 family efflux MFS transporter permease subunit
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  • STRAU_RS38955
  • WP_158692054.1
3609 - 4262 (+) TcmI family type II polyketide cyclase
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  • STRAU_RS10350
  • WP_016640229.1
4754 - 5182 (+) nuclear transport factor 2 family protein
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  • STRAU_RS10355
  • WP_078621122.1
5241 - 6050 (+) response regulator transcription factor
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  • STRAU_RS10360
  • WP_052029032.1
6151 - 7371 (+) cytochrome P450
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  • STRAU_RS10365
  • WP_037658546.1
7383 - 7577 (+) (4Fe-4S)-binding protein
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  • STRAU_RS10370
  • WP_016640233.1
7645 - 8115 (-) nuclear transport factor 2 family protein
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  • STRAU_RS41390
8333 - >8620 (+) TcmI family type II polyketide cyclase
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  • STRAU_RS41395
  • WP_037658559.1
8651 - 8983 (+) TcmI family type II polyketide cyclase
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  • STRAU_RS10380
  • WP_037658548.1
8980 - 10251 (+) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
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  • STRAU_RS10385
  • WP_037658550.1
10248 - 11444 (+) ketosynthase chain-length factor
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  • STRAU_RS10390
  • WP_016640237.1
11507 - 11773 (+) acyl carrier protein
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  • STRAU_RS10395
  • WP_016640238.1
  • fabG
11863 - 12648 (+) 3-oxoacyl-ACP reductase FabG
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  • STRAU_RS10400
  • WP_016640239.1
12682 - 13647 (+) aromatase/cyclase
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  • STRAU_RS10405
  • WP_016640240.1
13644 - 14558 (+) alpha/beta fold hydrolase
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Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Cleaned up synonym list
  • Fetch compound properties from PubChem
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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